| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 3/27/2026 | AUR | Johnston | Traded away | RMH | | After |
| 3/27/2026 | AUR | Wynns | Acquired via trade | RMH | | After |
| 3/27/2026 | RMH | Johnston | Acquired via trade | AUR | | After |
| 3/27/2026 | RMH | Wynns | Traded away | AUR | | After |
| 4/8/2026 | CED | Cruz,F | Placed on Injured List | | 4/7/2026 | Before |
| 4/8/2026 | CED | Detmers | Promoted to active roster | | | Before |
| 4/8/2026 | NHP | Cavalli | Demoted to reserve roster | | | Before |
| 4/8/2026 | NHP | Curtiss | Promoted to active roster | | | Before |
| 4/8/2026 | NHP | Spence | Demoted to reserve roster | | | Before |
| 4/8/2026 | NHP | Strowd | Promoted to active roster | | | Before |
| 4/8/2026 | PUE | Castellanos | Promoted to active roster | | | Before |
| 4/8/2026 | PUE | Lewis | Placed on Injured List | | 4/6/2026 | Before |
| 4/8/2026 | PUE | Sproat | Promoted to active roster | | | Before |
| 4/8/2026 | PUE | Vasil | Placed on Injured List | | 4/8/2026 | Before |
| 4/11/2026 | NHP | Arrighetti | Promoted to active roster | | | Before |
| 4/11/2026 | NHP | Curtiss | Demoted to reserve roster | | | Before |
| 4/11/2026 | NHP | Spence | Promoted to active roster | | | Before |
| 4/11/2026 | NHP | Strowd | Demoted to reserve roster | | | Before |
| 4/14/2026 | CAP | Ashby | Placed on Injured List | | 4/13/2026 | Before |
| 4/14/2026 | CAP | Holmes,G | Promoted to active roster | | | Before |
| 4/14/2026 | CAP | Schwellenbach | Placed on Injured List | | 4/13/2026 | Before |
| 4/14/2026 | CAP | Varland | Promoted to active roster | | | Before |
| 4/14/2026 | DSP | Darvish | Promoted to active roster | | | Before |
| 4/14/2026 | DSP | McLean | Demoted to reserve roster | | | Before |
| 4/17/2026 | CAP | Paddack | Promoted to active roster | | | Before |
| 4/17/2026 | CAP | Pfaadt | Promoted to active roster | | | Before |
| 4/17/2026 | CAP | Soriano,J | Placed on Injured List | | 4/15/2026 | Before |
| 4/17/2026 | CAP | Yamamoto | Placed on Injured List | | 4/16/2026 | Before |
| 4/17/2026 | RMH | Civale | Promoted to active roster | | | Before |
| 4/17/2026 | RMH | Lauer | Placed on Injured List | | 4/15/2026 | Before |
| 4/20/2026 | CLE | Sheehan | Promoted to active roster | | | Before |
| 4/20/2026 | CLE | Sugano | Demoted to reserve roster | | | Before |
| 4/20/2026 | CUY | Loftin | Promoted to active roster | | | Before |
| 4/20/2026 | CUY | Westburg | Placed on Injured List | | 4/18/2026 | Before |
| 4/20/2026 | OLL | Fedde | Placed on Injured List | | 4/20/2026 | Before |
| 4/20/2026 | OLL | Houck | Promoted to active roster | | | Before |
| 4/20/2026 | PBC | Bregman | Placed on Injured List | | 4/18/2026 | Before |
| 4/20/2026 | PBC | Tena | Promoted to active roster | | | Before |
| 4/20/2026 | RMH | Civale | Promoted to active roster | | | Before |
| 4/23/2026 | BOS | Stewart,S | Promoted to active roster | | | Before |
| 4/23/2026 | BOS | Vargas,I | Placed on Injured List | | 4/22/2026 | Before |
| 4/23/2026 | CGS | Flaherty | Traded away | RMH | | After |
| 4/23/2026 | CGS | Flaherty | Acquired via trade | RMH | | After |
| 4/23/2026 | CGS | Rogers,Tr | Traded away | RMH | | After |
| 4/23/2026 | CGS | Rogers,Tr | Acquired via trade | RMH | | After |
| 4/23/2026 | CGS | Walker,Jor | Traded away | RMH | | After |
| 4/23/2026 | CGS | Walker,Jor | Acquired via trade | RMH | | After |
| 4/23/2026 | PUE | Burleson | Placed on Injured List | | 4/21/2026 | Before |
| 4/23/2026 | PUE | Lewis | Activated from Injured List | | | Before |
| 4/23/2026 | PUE | Sproat | Demoted to reserve roster | | | Before |
| 4/23/2026 | PUE | Vasil | Activated from Injured List | | | Before |
| 4/23/2026 | RMH | Call | Placed on Injured List | | 4/22/2026 | Before |
| 4/23/2026 | RMH | Johnson,B | Promoted to active roster | | | Before |
| 4/23/2026 | RMH | Flaherty | Traded away | CGS | | After |
| 4/23/2026 | RMH | Flaherty | Acquired via trade | CGS | | After |
| 4/23/2026 | RMH | Rogers,Tr | Traded away | CGS | | After |
| 4/23/2026 | RMH | Rogers,Tr | Acquired via trade | CGS | | After |
| 4/23/2026 | RMH | Walker,Jor | Traded away | CGS | | After |
| 4/23/2026 | RMH | Walker,Jor | Acquired via trade | CGS | | After |
| 4/23/2026 | WTB | Contreras,R | Demoted to reserve roster | | | Before |
| 4/23/2026 | WTB | Jarvis | Promoted to active roster | | | Before |
| 4/26/2026 | CAP | Ashby | Activated from Injured List | | | Before |
| 4/26/2026 | CAP | Hall | Demoted to reserve roster | | | Before |
| 4/26/2026 | CAP | Paddack | Demoted to reserve roster | | | Before |
| 4/26/2026 | CAP | Yamamoto | Activated from Injured List | | | Before |
| 4/26/2026 | CED | Cruz,F | Activated from Injured List | | | Before |
| 4/26/2026 | CED | Detmers | Demoted to reserve roster | | | Before |
| 4/29/2026 | BOS | Muncy,Max | Traded away | NHP | | After |
| 4/29/2026 | BOS | Muncy,MP | Acquired via trade | NHP | | After |
| 4/29/2026 | NHP | Muncy,Max | Acquired via trade | BOS | | After |
| 4/29/2026 | NHP | Muncy,MP | Traded away | BOS | | After |
| 5/2/2026 | AUR | Lee,B | Promoted to active roster | | | Before |
| 5/2/2026 | AUR | Smith,Do | Placed on Injured List | | 5/2/2026 | Before |
| 5/2/2026 | CAP | Holmes,G | Demoted to reserve roster | | | Before |
| 5/2/2026 | CAP | Soriano,J | Activated from Injured List | | | Before |
| 5/2/2026 | RMH | Call | Activated from Injured List | | | Before |
| 5/2/2026 | RMH | Civale | Demoted to reserve roster | | | Before |
| 5/2/2026 | RMH | Johnson,B | Demoted to reserve roster | | | Before |
| 5/2/2026 | RMH | Lauer | Activated from Injured List | | | Before |
| 5/5/2026 | BOS | Stewart,S | Demoted to reserve roster | | | Before |
| 5/5/2026 | BOS | Vargas,I | Activated from Injured List | | | Before |
| 5/5/2026 | CAP | Pfaadt | Demoted to reserve roster | | | Before |
| 5/5/2026 | CAP | Schwellenbach | Activated from Injured List | | | Before |
| 5/5/2026 | CUY | Arias,G | Placed on Injured List | | 5/5/2026 | Before |
| 5/5/2026 | CUY | Baldwin,B | Promoted to active roster | | | Before |
| 5/5/2026 | NHP | Cavalli | Promoted to active roster | | | Before |
| 5/5/2026 | NHP | Wheeler | Placed on Injured List | | 5/3/2026 | Before |
| 5/5/2026 | PUE | Beeks | Placed on Injured List | | 5/4/2026 | Before |
| 5/5/2026 | PUE | Lee,D | Promoted to active roster | | | Before |
| 5/5/2026 | TOR | Alvarez,Y | Demoted to reserve roster | | | Before |
| 5/5/2026 | TOR | Brown,H | Placed on Injured List | | 5/1/2026 | Before |
| 5/5/2026 | TOR | Evans | Promoted to active roster | | | Before |
| 5/5/2026 | TOR | Garrett | Promoted to active roster | | | Before |
| 5/5/2026 | TOR | Jensen | Promoted to active roster | | | Before |
| 5/5/2026 | TOR | Raley,L | Demoted to reserve roster | | | Before |
| 5/8/2026 | OLL | Fedde | Activated from Injured List | | | Before |
| 5/8/2026 | OLL | Houck | Demoted to reserve roster | | | Before |
| 5/8/2026 | TOR | Bergert | Demoted to reserve roster | | | Before |
| 5/8/2026 | TOR | Keith | Placed on Injured List | | 5/7/2026 | Before |
| 5/8/2026 | TOR | Miller,Br | Promoted to active roster | | | Before |
| 5/8/2026 | TOR | Raley,L | Promoted to active roster | | | Before |
| 5/11/2026 | CAP | Holmes,G | Promoted to active roster | | | Before |
| 5/11/2026 | CAP | Schwellenbach | Placed on Injured List | | 5/11/2026 | Before |
| 5/11/2026 | DSP | Boyle | Demoted to reserve roster | | | Before |
| 5/11/2026 | DSP | Carlson | Promoted to active roster | | | Before |
| 5/11/2026 | PBC | Bregman | Activated from Injured List | | | Before |
| 5/11/2026 | PBC | Tena | Demoted to reserve roster | | | Before |
| 5/13/2026 | CLE | Banks | Traded away | HAV | | After |
| 5/13/2026 | CLE | Henriquez,E | Acquired via trade | HAV | | After |
| 5/13/2026 | HAV | Banks | Acquired via trade | CLE | | After |
| 5/13/2026 | HAV | Henriquez,E | Traded away | CLE | | After |
| 5/14/2026 | BOS | Graceffo | Promoted to active roster | | | Before |
| 5/14/2026 | BOS | Hanifee | Promoted to active roster | | | Before |
| 5/14/2026 | BOS | Horton | Placed on Injured List | | 5/14/2026 | Before |
| 5/14/2026 | BOS | Taylor,G | Placed on Injured List | | 5/11/2026 | Before |
| 5/14/2026 | CAP | Pfaadt | Promoted to active roster | | | Before |
| 5/14/2026 | CAP | Yamamoto | Placed on Injured List | | 5/13/2026 | Before |
| 5/14/2026 | CLE | Henriquez,E | Promoted to active roster | | | Before |
| 5/14/2026 | HAV | Sale | Placed on Injured List | | 5/11/2026 | Before |
| 5/14/2026 | SPR | Abbott | Placed on Injured List | | 5/6/2026 | Before |
| 5/14/2026 | SPR | Jobe | Promoted to active roster | | | Before |
| 5/16/2026 | CUY | Acuna,R | Traded away | NHP | | After |
| 5/16/2026 | CUY | Caissie | Traded away | NHP | | After |
| 5/16/2026 | CUY | Chandler | Traded away | NHP | | After |
| 5/16/2026 | CUY | deGrom | Acquired via trade | NHP | | After |
| 5/16/2026 | CUY | Springer | Acquired via trade | NHP | | After |
| 5/16/2026 | CUY | Svanson | Acquired via trade | NHP | | After |
| 5/16/2026 | NHP | Acuna,R | Acquired via trade | CUY | | After |
| 5/16/2026 | NHP | Caissie | Acquired via trade | CUY | | After |
| 5/16/2026 | NHP | Chandler | Acquired via trade | CUY | | After |
| 5/16/2026 | NHP | deGrom | Traded away | CUY | | After |
| 5/16/2026 | NHP | Springer | Traded away | CUY | | After |
| 5/16/2026 | NHP | Svanson | Traded away | CUY | | After |
| 5/17/2026 | AUR | Lee,B | Demoted to reserve roster | | | Before |
| 5/17/2026 | AUR | Smith,Do | Activated from Injured List | | | Before |
| 5/17/2026 | CUY | deGrom | Placed on Injured List | | 5/15/2026 | Before |
| 5/17/2026 | CUY | Murphy,C | Demoted to reserve roster | | | Before |
| 5/17/2026 | NHP | Curtiss | Promoted to active roster | | | Before |
| 5/17/2026 | NHP | Strowd | Promoted to active roster | | | Before |
| 5/17/2026 | PEI | Higashioka | Placed on Injured List | | 5/12/2026 | Before |
| 5/17/2026 | PEI | Stallings | Promoted to active roster | | | Before |
| 5/17/2026 | PUE | Anderson,G | Demoted to reserve roster | | | Before |
| 5/17/2026 | PUE | Beeks | Activated from Injured List | | | Before |
| 5/17/2026 | PUE | Bieber | Promoted to active roster | | | Before |
| 5/17/2026 | PUE | Burleson | Activated from Injured List | | | Before |
| 5/17/2026 | PUE | Burnes | Demoted to reserve roster | | | Before |
| 5/17/2026 | PUE | Castellanos | Demoted to reserve roster | | | Before |
| 5/17/2026 | PUE | Enright | Promoted to active roster | | | Before |
| 5/17/2026 | PUE | Hancock | Promoted to active roster | | | Before |
| 5/17/2026 | PUE | Henriquez,R | Demoted to reserve roster | | | Before |
| 5/17/2026 | PUE | Mlodzinski | Demoted to reserve roster | | | Before |
| 5/19/2026 | HOL | Ferguson,C | Acquired via trade | NHP | | After |
| 5/19/2026 | HOL | Mey | Traded away | NHP | | After |
| 5/19/2026 | NHP | Ferguson,C | Traded away | HOL | | After |
| 5/19/2026 | NHP | Mey | Acquired via trade | HOL | | After |
| 5/20/2026 | AUR | Bautista | Placed on Injured List | | 5/20/2026 | Before |
| 5/20/2026 | AUR | Wynns | Promoted to active roster | | | Before |
| 5/20/2026 | HOL | Vargas,C | Demoted to reserve roster | | | Before |
| 5/20/2026 | NHP | Chandler | Promoted to active roster | | | Before |
| 5/20/2026 | NHP | Curtiss | Demoted to reserve roster | | | Before |
| 5/20/2026 | NHP | Maxwell | Promoted to active roster | | | Before |
| 5/20/2026 | NHP | Mey | Promoted to active roster | | | Before |
| 5/20/2026 | NHP | Muncy,Max | Placed on Injured List | | 5/18/2026 | Before |
| 5/20/2026 | NHP | Strowd | Demoted to reserve roster | | | Before |
| 5/20/2026 | NHP | Wheeler | Activated from Injured List | | | Before |
| 5/20/2026 | RMH | Cortes,C | Promoted to active roster | | | Before |
| 5/20/2026 | RMH | Gurriel,L | Demoted to reserve roster | | | Before |
| 5/20/2026 | TOR | Brown,H | Activated from Injured List | | | Before |
| 5/20/2026 | TOR | Greene,H | Placed on Injured List | | 5/17/2026 | Before |
| 5/23/2026 | DSP | Darvish | Placed on Injured List | | 5/17/2026 | Before |
| 5/23/2026 | DSP | Gil | Placed on Injured List | | 5/15/2026 | Before |
| 5/23/2026 | DSP | Knack | Promoted to active roster | | | Before |
| 5/23/2026 | DSP | McLean | Promoted to active roster | | | Before |
| 5/23/2026 | NHP | Chandler | Promoted to active roster | | | Before |
| 5/23/2026 | NHP | Curtiss | Demoted to reserve roster | | | Before |
| 5/23/2026 | NHP | Jones,N | Promoted to active roster | | | Before |
| 5/23/2026 | NHP | Maxwell | Demoted to reserve roster | | | Before |
| 5/23/2026 | NHP | Maxwell | Promoted to active roster | | | Before |
| 5/23/2026 | NHP | Strowd | Demoted to reserve roster | | | Before |
| 5/23/2026 | NHP | Wheeler | Activated from Injured List | | | Before |
| 5/26/2026 | AUR | Bradish | Promoted to active roster | | | Before |
| 5/26/2026 | AUR | Castillo,LM | Demoted to reserve roster | | | Before |
| 5/26/2026 | AUR | Roupp | Demoted to reserve roster | | | Before |
| 5/26/2026 | AUR | Waldrep | Promoted to active roster | | | Before |
| 5/26/2026 | CAP | Pfaadt | Demoted to reserve roster | | | Before |
| 5/26/2026 | CAP | Yamamoto | Activated from Injured List | | | Before |
| 5/26/2026 | CUY | deGrom | Activated from Injured List | | | Before |
| 5/26/2026 | CUY | Loftin | Demoted to reserve roster | | | Before |
| 5/26/2026 | CUY | Melton,T | Demoted to reserve roster | | | Before |
| 5/26/2026 | CUY | Westburg | Activated from Injured List | | | Before |
| 5/26/2026 | DSP | Englert | Demoted to reserve roster | | | Before |
| 5/26/2026 | DSP | Romano | Promoted to active roster | | | Before |
| 5/29/2026 | BOS | Hanifee | Demoted to reserve roster | | | Before |
| 5/29/2026 | BOS | Taylor,G | Activated from Injured List | | | Before |
| 5/29/2026 | CGS | Ferrer | Promoted to active roster | | | Before |
| 5/29/2026 | CGS | Rogers,Tr | Placed on Injured List | | 5/28/2026 | Before |
| 5/29/2026 | DUR | Myers,T | Promoted to active roster | | | Before |
| 5/29/2026 | DUR | Woo | Placed on Injured List | | 5/25/2026 | Before |
| 5/29/2026 | RMH | Bichette | Placed on Injured List | | 5/22/2026 | Before |
| 5/29/2026 | RMH | Cortes,C | Placed on Injured List | | 5/28/2026 | Before |
| 5/29/2026 | RMH | Gurriel,L | Promoted to active roster | | | Before |
| 5/29/2026 | RMH | Walls | Promoted to active roster | | | Before |
| 5/29/2026 | TOR | Bergert | Promoted to active roster | | | Before |
| 5/29/2026 | TOR | Jensen | Demoted to reserve roster | | | Before |
| 5/29/2026 | TOR | Keith | Activated from Injured List | | | Before |
| 5/29/2026 | TOR | Miller,Br | Demoted to reserve roster | | | Before |
| 5/29/2026 | TOR | Raley,B | Demoted to reserve roster | | | Before |
| 5/29/2026 | TOR | Stephenson,R | Promoted to active roster | | | Before |
| 6/1/2026 | BOS | Graceffo | Demoted to reserve roster | | | Before |
| 6/1/2026 | BOS | Horton | Activated from Injured List | | | Before |
| 6/1/2026 | CAP | Holmes,G | Placed on Injured List | | 5/31/2026 | Before |
| 6/1/2026 | CAP | Pfaadt | Promoted to active roster | | | Before |
| 6/1/2026 | CED | Monasterio | Promoted to active roster | | | Before |
| 6/1/2026 | CED | Tovar | Placed on Injured List | | 5/30/2026 | Before |
| 6/1/2026 | NDF | Kayfus | Promoted to active roster | | | Before |
| 6/1/2026 | NDF | Loperfido | Demoted to reserve roster | | | Before |
| 6/4/2026 | PUE | Castellanos | Promoted to active roster | | | Before |
| 6/4/2026 | PUE | Stott | Placed on Injured List | | 6/4/2026 | Before |
| 6/4/2026 | RMH | Bichette | Activated from Injured List | | | Before |
| 6/4/2026 | RMH | Walls | Demoted to reserve roster | | | Before |
| 6/4/2026 | SPR | Abbott | Activated from Injured List | | | Before |
| 6/4/2026 | SPR | Jobe | Demoted to reserve roster | | | Before |
| 6/10/2026 | AUR | Bautista | Activated from Injured List | | | Before |
| 6/10/2026 | AUR | Lee,B | Promoted to active roster | | | Before |
| 6/10/2026 | AUR | Sanoja | Demoted to reserve roster | | | Before |
| 6/10/2026 | AUR | Wynns | Demoted to reserve roster | | | Before |
| 6/10/2026 | CUY | Arias,G | Activated from Injured List | | | Before |
| 6/10/2026 | CUY | Baldwin,B | Demoted to reserve roster | | | Before |
| 6/10/2026 | DSP | Darvish | Activated from Injured List | | | Before |
| 6/10/2026 | DSP | Kopech | Promoted to active roster | | | Before |
| 6/10/2026 | DSP | Taillon | Demoted to reserve roster | | | Before |
| 6/10/2026 | DSP | White,E | Demoted to reserve roster | | | Before |
| 6/10/2026 | NHP | Dezenzo | Promoted to active roster | | | Before |
| 6/10/2026 | NHP | Perkins,J | Placed on Injured List | | 6/10/2026 | Before |
| 6/10/2026 | OLL | Houck | Promoted to active roster | | | Before |
| 6/10/2026 | OLL | Patrick | Placed on Injured List | | 6/10/2026 | Before |
| 6/13/2026 | CAP | Paddack | Promoted to active roster | | | Before |
| 6/13/2026 | CAP | Yamamoto | Placed on Injured List | | 6/12/2026 | Before |
| 6/16/2026 | DSP | Gil | Activated from Injured List | | | Before |
| 6/16/2026 | DSP | McLean | Demoted to reserve roster | | | Before |
| 6/16/2026 | HAV | Harrison | Demoted to reserve roster | | | Before |
| 6/16/2026 | HAV | Sale | Activated from Injured List | | | Before |
| 6/16/2026 | NHP | Caissie | Promoted to active roster | | | Before |
| 6/16/2026 | NHP | Garcia,LV | Placed on Injured List | | 6/16/2026 | Before |
| 6/16/2026 | PUE | Martin,A | Demoted to reserve roster | | | Before |
| 6/16/2026 | PUE | Stott | Activated from Injured List | | | Before |
| 6/18/2026 | NDF | Brown,B | Traded away | PBC | | After |
| 6/18/2026 | NDF | Duran,Ja | Acquired via trade | PBC | | After |
| 6/18/2026 | NDF | Latz | Traded away | PBC | | After |
| 6/18/2026 | NDF | Narvaez,C | Acquired via trade | PBC | | After |
| 6/18/2026 | PBC | Brown,B | Acquired via trade | NDF | | After |
| 6/18/2026 | PBC | Duran,Ja | Traded away | NDF | | After |
| 6/18/2026 | PBC | Latz | Acquired via trade | NDF | | After |
| 6/18/2026 | PBC | Narvaez,C | Traded away | NDF | | After |
| 6/19/2026 | AUR | Bradish | Demoted to reserve roster | | | Before |
| 6/19/2026 | AUR | Cantillo | Promoted to active roster | | | Before |
| 6/19/2026 | AUR | Castillo,LM | Promoted to active roster | | | Before |
| 6/19/2026 | AUR | Waldrep | Demoted to reserve roster | | | Before |
| 6/19/2026 | DUR | Myers,T | Demoted to reserve roster | | | Before |
| 6/19/2026 | DUR | Woo | Activated from Injured List | | | Before |
| 6/19/2026 | NDF | Beeter | Promoted to active roster | | | Before |
| 6/19/2026 | NDF | Bibee | Placed on Injured List | | 6/15/2026 | Before |
| 6/19/2026 | NDF | Erceg | Promoted to active roster | | | Before |
| 6/19/2026 | NDF | Kayfus | Demoted to reserve roster | | | Before |
| 6/19/2026 | NDF | Pederson | Demoted to reserve roster | | | Before |
| 6/19/2026 | NDF | Perez,M | Promoted to active roster | | | Before |
| 6/19/2026 | NDF | Ritter | Promoted to active roster | | | Before |
| 6/19/2026 | NDF | Saalfrank | Demoted to reserve roster | | | Before |
| 6/19/2026 | PEI | Higashioka | Activated from Injured List | | | Before |
| 6/19/2026 | PEI | Stallings | Demoted to reserve roster | | | Before |
| 6/19/2026 | PUE | Alvarez,A | Promoted to active roster | | | Before |
| 6/19/2026 | PUE | Anderson,G | Promoted to active roster | | | Before |
| 6/19/2026 | PUE | Beeks | Demoted to reserve roster | | | Before |
| 6/19/2026 | PUE | Flexen | Promoted to active roster | | | Before |
| 6/19/2026 | PUE | Kinley | Demoted to reserve roster | | | Before |
| 6/19/2026 | PUE | Kolek | Placed on Injured List | | 6/18/2026 | Before |
| 6/22/2026 | BOS | Heineman | Placed on Injured List | | 6/22/2026 | Before |
| 6/22/2026 | BOS | Wong | Promoted to active roster | | | Before |
| 6/22/2026 | CED | Cruz,F | Placed on Injured List | | 6/22/2026 | Before |
| 6/22/2026 | CED | Detmers | Promoted to active roster | | | Before |
| 6/22/2026 | HOL | Fermin,JM | Promoted to active roster | | | Before |
| 6/22/2026 | HOL | Flores,W | Demoted to reserve roster | | | Before |
| 6/22/2026 | HOL | Gusto | Promoted to active roster | | | Before |
| 6/22/2026 | HOL | Skubal | Placed on Injured List | | 6/20/2026 | Before |
| 6/22/2026 | TOR | Bergert | Demoted to reserve roster | | | Before |
| 6/22/2026 | TOR | Greene,H | Activated from Injured List | | | Before |
| 6/22/2026 | TOR | Keith | Placed on Injured List | | 6/21/2026 | Before |
| 6/22/2026 | TOR | Miller,Br | Promoted to active roster | | | Before |
| 6/22/2026 | TOR | Soler | Promoted to active roster | | | Before |
| 6/25/2026 | AUR | Ortiz,L | Demoted to reserve roster | | | Before |
| 6/25/2026 | AUR | Waldrep | Promoted to active roster | | | Before |
| 6/25/2026 | CAP | Langford | Placed on Injured List | | 6/23/2026 | Before |
| 6/25/2026 | CAP | Mastrobuoni | Promoted to active roster | | | Before |
| 6/25/2026 | CAP | Paddack | Demoted to reserve roster | | | Before |
| 6/25/2026 | CAP | Schwellenbach | Activated from Injured List | | | Before |
| 6/25/2026 | CED | Herrera,J | Promoted to active roster | | | Before |
| 6/25/2026 | CED | Iglesias,J | Promoted to active roster | | | Before |
| 6/25/2026 | CED | McGuire | Demoted to reserve roster | | | Before |
| 6/25/2026 | CED | Nunez,N | Demoted to reserve roster | | | Before |
| 6/25/2026 | CGS | Estrada,J | Demoted to reserve roster | | | Before |
| 6/25/2026 | CGS | Rogers,Tr | Activated from Injured List | | | Before |
| 6/25/2026 | CLE | Bradley | Placed on Injured List | | 6/23/2026 | Before |
| 6/25/2026 | CLE | Kim,Ha | Demoted to reserve roster | | | Before |
| 6/25/2026 | CLE | Sheehan | Demoted to reserve roster | | | Before |
| 6/25/2026 | CLE | Sugano | Promoted to active roster | | | Before |
| 6/25/2026 | CLE | Valera | Demoted to reserve roster | | | Before |
| 6/25/2026 | CLE | Valera | Promoted to active roster | | | Before |
| 6/25/2026 | CLE | Valera | Promoted to active roster | | | Before |
| 6/25/2026 | CLE | Woodruff | Promoted to active roster | | | Before |
| 6/25/2026 | DSP | Beavers | Promoted to active roster | | | Before |
| 6/25/2026 | DSP | Farmer | Placed on Injured List | | 6/25/2026 | Before |
| 6/25/2026 | DSP | Long | Placed on Injured List | | 6/25/2026 | Before |
| 6/25/2026 | DSP | Morton | Promoted to active roster | | | Before |
| 6/25/2026 | HOL | Flores,W | Promoted to active roster | | | Before |
| 6/25/2026 | HOL | Hernandez,E | Demoted to reserve roster | | | Before |
| 6/25/2026 | OLL | Criswell | Promoted to active roster | | | Before |
| 6/25/2026 | OLL | Henderson,L | Placed on Injured List | | 6/22/2026 | Before |
| 6/25/2026 | OLL | Klein | Promoted to active roster | | | Before |
| 6/25/2026 | OLL | Martinez,J | Demoted to reserve roster | | | Before |
| 6/25/2026 | OLL | Pallante | Placed on Injured List | | 6/23/2026 | Before |
| 6/25/2026 | OLL | Patrick | Activated from Injured List | | | Before |
| 6/25/2026 | PBC | Fraley | Promoted to active roster | | | Before |
| 6/25/2026 | PBC | Latz | Demoted to reserve roster | | | Before |
| 6/25/2026 | PUE | Beeks | Promoted to active roster | | | Before |
| 6/25/2026 | PUE | Enright | Demoted to reserve roster | | | Before |
| 6/25/2026 | PUE | Hancock | Demoted to reserve roster | | | Before |
| 6/25/2026 | PUE | Henriquez,R | Promoted to active roster | | | Before |
| 6/25/2026 | TOR | Bergert | Promoted to active roster | | | Before |
| 6/25/2026 | TOR | Miller,Br | Demoted to reserve roster | | | Before |
| 6/28/2026 | BOS | Hanifee | Promoted to active roster | | | Before |
| 6/28/2026 | BOS | Rasmussen | Placed on Injured List | | 6/26/2026 | Before |
| 6/28/2026 | CED | Kirby | Placed on Injured List | | 6/26/2026 | Before |
| 6/28/2026 | CED | Yesavage | Promoted to active roster | | | Before |
| 6/28/2026 | NHP | Caissie | Demoted to reserve roster | | | Before |
| 6/28/2026 | NHP | Dezenzo | Demoted to reserve roster | | | Before |
| 6/28/2026 | NHP | Garcia,LV | Activated from Injured List | | | Before |
| 6/28/2026 | NHP | Muncy,Max | Activated from Injured List | | | Before |
| 6/28/2026 | TOR | Bergert | Demoted to reserve roster | | | Before |
| 6/28/2026 | TOR | Miller,Br | Promoted to active roster | | | Before |
| 6/28/2026 | TOR | Stephenson,R | Demoted to reserve roster | | | Before |
| 7/1/2026 | CAP | Pfaadt | Demoted to reserve roster | | | Before |
| 7/1/2026 | CAP | Yamamoto | Activated from Injured List | | | Before |
| 7/1/2026 | HAV | Ibanez | Promoted to active roster | | | Before |
| 7/1/2026 | HAV | Meyers | Placed on Injured List | | 6/23/2026 | Before |
| 7/1/2026 | HOL | Ragans | Demoted to reserve roster | | | Before |
| 7/1/2026 | HOL | Skubal | Activated from Injured List | | | Before |
| 7/1/2026 | RMH | Cortes,C | Activated from Injured List | | | Before |
| 7/1/2026 | RMH | Cortes,C | Demoted to reserve roster | | | Before |
| 7/1/2026 | RMH | Torres | Placed on Injured List | | 6/30/2026 | Before |
| 7/1/2026 | RMH | Urias,L | Promoted to active roster | | | Before |
| 7/4/2026 | CAP | Rodriguez,M | Demoted to reserve roster | | | Before |
| 7/4/2026 | CAP | Weissert | Promoted to active roster | | | Before |
| 7/4/2026 | CUY | Alcantara,Sa | Promoted to active roster | | | Before |
| 7/4/2026 | CUY | Arias,G | Placed on Injured List | | 6/25/2026 | Before |
| 7/4/2026 | CUY | Baldwin,B | Promoted to active roster | | | Before |
| 7/4/2026 | CUY | Kelly,Me | Demoted to reserve roster | | | Before |
| 7/4/2026 | CUY | Murphy,C | Promoted to active roster | | | Before |
| 7/4/2026 | CUY | Palencia | Demoted to reserve roster | | | Before |
| 7/4/2026 | DSP | Boyle | Promoted to active roster | | | Before |
| 7/4/2026 | DSP | Knack | Demoted to reserve roster | | | Before |
| 7/4/2026 | DSP | Kopech | Demoted to reserve roster | | | Before |
| 7/4/2026 | DSP | Taillon | Promoted to active roster | | | Before |
| 7/4/2026 | HAV | Harrison | Promoted to active roster | | | Before |
| 7/4/2026 | HAV | Slaten | Demoted to reserve roster | | | Before |
| 7/4/2026 | NDF | Bibee | Activated from Injured List | | | Before |
| 7/4/2026 | NDF | Narvaez,C | Promoted to active roster | | | Before |
| 7/4/2026 | NDF | Sanchez,G | Demoted to reserve roster | | | Before |
| 7/4/2026 | NDF | Snell | Demoted to reserve roster | | | Before |
| 7/4/2026 | TOR | Alvarez,Y | Promoted to active roster | | | Before |
| 7/4/2026 | TOR | Amaya,M | Promoted to active roster | | | Before |
| 7/4/2026 | TOR | Goodman | Demoted to reserve roster | | | Before |
| 7/4/2026 | TOR | Miller,E | Demoted to reserve roster | | | Before |
| 7/4/2026 | TOR | Soler | Demoted to reserve roster | | | Before |
| 7/4/2026 | TOR | Stephenson,R | Promoted to active roster | | | Before |
| 7/6/2026 | DSP | Profar | Traded away | NDF | | After |
| 7/6/2026 | DSP | Rengifo | Acquired via trade | NDF | | After |
| 7/6/2026 | DSP | Sanchez,G | Acquired via trade | NDF | | After |
| 7/6/2026 | DSP | Sheets | Acquired via trade | NDF | | After |
| 7/6/2026 | HAV | Alcantara,K | Traded away | NHP | | After |
| 7/6/2026 | HAV | Caballero | Traded away | NHP | | After |
| 7/6/2026 | HAV | Kemp | Acquired via trade | NHP | | After |
| 7/6/2026 | HAV | Kwan | Acquired via trade | NHP | | After |
| 7/6/2026 | HAV | Scherzer | Acquired via trade | NHP | | After |
| 7/6/2026 | NDF | Profar | Acquired via trade | DSP | | After |
| 7/6/2026 | NDF | Rengifo | Traded away | DSP | | After |
| 7/6/2026 | NDF | Sanchez,G | Traded away | DSP | | After |
| 7/6/2026 | NDF | Sheets | Traded away | DSP | | After |
| 7/6/2026 | NHP | Alcantara,K | Acquired via trade | HAV | | After |
| 7/6/2026 | NHP | Caballero | Acquired via trade | HAV | | After |
| 7/6/2026 | NHP | Kemp | Traded away | HAV | | After |
| 7/6/2026 | NHP | Kwan | Traded away | HAV | | After |
| 7/6/2026 | NHP | Scherzer | Traded away | HAV | | After |
| 7/7/2026 | CLE | Dominguez,J | Promoted to active roster | | | Before |
| 7/7/2026 | CLE | Woodruff | Demoted to reserve roster | | | Before |
| 7/7/2026 | DSP | Rengifo | Promoted to active roster | | | Before |
| 7/7/2026 | DSP | Schuemann | Demoted to reserve roster | | | Before |
| 7/7/2026 | HAV | Scherzer | Demoted to reserve roster | | | Before |
| 7/7/2026 | HAV | Schneider | Demoted to reserve roster | | | Before |
| 7/7/2026 | NDF | Kelly,Car | Placed on Injured List | | 7/5/2026 | Before |
| 7/7/2026 | NDF | Millas | Signed | | | Before |
| 7/7/2026 | NHP | Dezenzo | Promoted to active roster | | | Before |
| 7/7/2026 | PUE | Fulford | Promoted to active roster | | | Before |
| 7/7/2026 | PUE | Langeliers | Placed on Injured List | | 7/7/2026 | Before |
| 7/9/2026 | AUR | Castillo,LM | Traded away | NHP | | After |
| 7/9/2026 | AUR | Nelson,R | Acquired via trade | NHP | | After |
| 7/9/2026 | AUR | Strowd | Acquired via trade | NHP | | After |
| 7/9/2026 | CLE | Bellozo | Acquired via trade | HOL | | After |
| 7/9/2026 | CLE | Leiter,M | Acquired via trade | HOL | | After |
| 7/9/2026 | CLE | Manaea | Acquired via trade | HOL | | After |
| 7/9/2026 | CLE | Woodruff | Traded away | HOL | | After |
| 7/9/2026 | HOL | Bellozo | Traded away | CLE | | After |
| 7/9/2026 | HOL | Leiter,M | Traded away | CLE | | After |
| 7/9/2026 | HOL | Manaea | Traded away | CLE | | After |
| 7/9/2026 | HOL | Woodruff | Acquired via trade | CLE | | After |
| 7/9/2026 | NHP | Castillo,LM | Acquired via trade | AUR | | After |
| 7/9/2026 | NHP | Nelson,R | Traded away | AUR | | After |
| 7/9/2026 | NHP | Strowd | Traded away | AUR | | After |
| 7/10/2026 | CAP | Hall | Promoted to active roster | | | Before |
| 7/10/2026 | CAP | Nance | Placed on Injured List | | 7/8/2026 | Before |
| 7/10/2026 | CLE | Bellozo | Promoted to active roster | | | Before |
| 7/10/2026 | CLE | Bradley | Activated from Injured List | | | Before |
| 7/10/2026 | CLE | Carter | Placed on Injured List | | 6/28/2026 | Before |
| 7/10/2026 | CLE | Laureano | Placed on Injured List | | 7/9/2026 | Before |
| 7/10/2026 | CLE | Leiter,M | Promoted to active roster | | | Before |
| 7/10/2026 | CLE | Manaea | Promoted to active roster | | | Before |
| 7/10/2026 | CLE | Saggese | Promoted to active roster | | | Before |
| 7/10/2026 | CLE | Sasaki | Placed on Injured List | | 6/26/2026 | Before |
| 7/10/2026 | CLE | Sugano | Placed on Injured List | | 6/27/2026 | Before |
| 7/10/2026 | DSP | Schneemann | Placed on Injured List | | 7/8/2026 | Before |
| 7/10/2026 | DSP | Schuemann | Promoted to active roster | | | Before |
| 7/10/2026 | HOL | Fermin,JM | Demoted to reserve roster | | | Before |
| 7/10/2026 | HOL | Woodruff | Promoted to active roster | | | Before |
| 7/10/2026 | NHP | Fernandez,Y | Promoted to active roster | | | Before |
| 7/10/2026 | NHP | Perkins,J | Activated from Injured List | | | Before |
| 7/10/2026 | NHP | Perkins,J | Demoted to reserve roster | | | Before |
| 7/10/2026 | OLL | Houck | Demoted to reserve roster | | | Before |
| 7/10/2026 | OLL | Pallante | Activated from Injured List | | | Before |
| 7/10/2026 | PUE | Bieber | Demoted to reserve roster | | | Before |
| 7/10/2026 | PUE | Kolek | Activated from Injured List | | | Before |
| 7/10/2026 | RMH | Gurriel,L | Placed on Injured List | | 7/9/2026 | Before |
| 7/10/2026 | RMH | Johnson,B | Promoted to active roster | | | Before |
| 7/10/2026 | RMH | Torres | Activated from Injured List | | | Before |
| 7/10/2026 | RMH | Urias,L | Demoted to reserve roster | | | Before |
| 7/12/2026 | CGS | Arraez | Traded away | NHP | | After |
| 7/12/2026 | CGS | Fernandez,Y | Acquired via trade | NHP | | After |
| 7/12/2026 | CGS | Kirk | Acquired via trade | NHP | | After |
| 7/12/2026 | CGS | Realmuto | Traded away | NHP | | After |
| 7/12/2026 | DUR | Curtiss | Acquired via trade | NHP | | After |
| 7/12/2026 | DUR | Muncy,Max | Acquired via trade | NHP | | After |
| 7/12/2026 | DUR | Story | Traded away | NHP | | After |
| 7/12/2026 | NHP | Arraez | Acquired via trade | CGS | | After |
| 7/12/2026 | NHP | Curtiss | Traded away | DUR | | After |
| 7/12/2026 | NHP | Fernandez,Y | Traded away | CGS | | After |
| 7/12/2026 | NHP | Kirk | Traded away | CGS | | After |
| 7/12/2026 | NHP | Muncy,Max | Traded away | DUR | | After |
| 7/12/2026 | NHP | Realmuto | Acquired via trade | CGS | | After |
| 7/12/2026 | NHP | Story | Acquired via trade | DUR | | After |
| 7/13/2026 | AUR | Cantillo | Demoted to reserve roster | | | Before |
| 7/13/2026 | AUR | Ortiz,L | Promoted to active roster | | | Before |
| 7/13/2026 | AUR | Peguero,J | Demoted to reserve roster | | | Before |
| 7/13/2026 | AUR | Strowd | Promoted to active roster | | | Before |
| 7/13/2026 | AUR | Waldrep | Demoted to reserve roster | | | Before |
| 7/13/2026 | AUR | Wynns | Promoted to active roster | | | Before |
| 7/13/2026 | BOS | Hanifee | Demoted to reserve roster | | | Before |
| 7/13/2026 | BOS | Heineman | Activated from Injured List | | | Before |
| 7/13/2026 | BOS | Rasmussen | Activated from Injured List | | | Before |
| 7/13/2026 | BOS | Wong | Demoted to reserve roster | | | Before |
| 7/13/2026 | CUY | Alcantara,Sa | Placed on Injured List | | 7/10/2026 | Before |
| 7/13/2026 | CUY | Arias,G | Activated from Injured List | | | Before |
| 7/13/2026 | CUY | Baldwin,B | Demoted to reserve roster | | | Before |
| 7/13/2026 | CUY | Kelly,Me | Promoted to active roster | | | Before |
| 7/13/2026 | DUR | Curtiss | Promoted to active roster | | | Before |
| 7/13/2026 | DUR | Grichuk | Promoted to active roster | | | Before |
| 7/13/2026 | DUR | Stewart,B | Demoted to reserve roster | | | Before |
| 7/13/2026 | DUR | Vierling | Demoted to reserve roster | | | Before |
| 7/15/2026 | CUY | Arias,G | Traded away | TOR | | After |
| 7/15/2026 | CUY | Bubic | Traded away | HAV | | After |
| 7/15/2026 | CUY | deGrom | Traded away | HAV | | After |
| 7/15/2026 | CUY | Early | Acquired via trade | HAV | | After |
| 7/15/2026 | CUY | Fisher | Traded away | NDF | | After |
| 7/15/2026 | CUY | Freeman,F | Traded away | TOR | | After |
| 7/15/2026 | CUY | Garcia,B | Acquired via trade | HAV | | After |
| 7/15/2026 | CUY | Harrison | Acquired via trade | HAV | | After |
| 7/15/2026 | CUY | Kelly,Me | Traded away | NDF | | After |
| 7/15/2026 | CUY | Kemp | Acquired via trade | HAV | | After |
| 7/15/2026 | CUY | Marte,N | Traded away | HAV | | After |
| 7/15/2026 | CUY | Moreno | Traded away | HAV | | After |
| 7/15/2026 | CUY | Outman | Acquired via trade | NDF | | After |
| 7/15/2026 | CUY | Paredes | Acquired via trade | TOR | | After |
| 7/15/2026 | CUY | Scherzer | Acquired via trade | HAV | | After |
| 7/15/2026 | CUY | Snell | Acquired via trade | NDF | | After |
| 7/15/2026 | CUY | Urias,R | Acquired via trade | TOR | | After |
| 7/15/2026 | CUY | Verlander | Acquired via trade | HAV | | After |
| 7/15/2026 | HAV | Bubic | Acquired via trade | CUY | | After |
| 7/15/2026 | HAV | deGrom | Acquired via trade | CUY | | After |
| 7/15/2026 | HAV | Early | Traded away | CUY | | After |
| 7/15/2026 | HAV | Garcia,B | Traded away | CUY | | After |
| 7/15/2026 | HAV | Harrison | Traded away | CUY | | After |
| 7/15/2026 | HAV | Kemp | Traded away | CUY | | After |
| 7/15/2026 | HAV | Marte,N | Acquired via trade | CUY | | After |
| 7/15/2026 | HAV | Moreno | Acquired via trade | CUY | | After |
| 7/15/2026 | HAV | Scherzer | Traded away | CUY | | After |
| 7/15/2026 | HAV | Verlander | Traded away | CUY | | After |
| 7/15/2026 | NDF | Fisher | Acquired via trade | CUY | | After |
| 7/15/2026 | NDF | Kelly,Me | Acquired via trade | CUY | | After |
| 7/15/2026 | NDF | Outman | Traded away | CUY | | After |
| 7/15/2026 | NDF | Snell | Traded away | CUY | | After |
| 7/15/2026 | TOR | Arias,G | Acquired via trade | CUY | | After |
| 7/15/2026 | TOR | Freeman,F | Acquired via trade | CUY | | After |
| 7/15/2026 | TOR | Paredes | Traded away | CUY | | After |
| 7/15/2026 | TOR | Urias,R | Traded away | CUY | | After |
| 7/16/2026 | BOS | Stewart,S | Promoted to active roster | | | Before |
| 7/16/2026 | BOS | Vargas,I | Placed on Injured List | | 7/12/2026 | Before |
| 7/16/2026 | CAP | Langford | Activated from Injured List | | | Before |
| 7/16/2026 | CAP | Mastrobuoni | Demoted to reserve roster | | | Before |
| 7/16/2026 | CED | Casparius | Demoted to reserve roster | | | Before |
| 7/16/2026 | CED | Cruz,F | Activated from Injured List | | | Before |
| 7/16/2026 | CED | Monasterio | Demoted to reserve roster | | | Before |
| 7/16/2026 | CED | Nunez,N | Promoted to active roster | | | Before |
| 7/16/2026 | CUY | Funderburk | Promoted to active roster | | | Before |
| 7/16/2026 | CUY | Harrison | Demoted to reserve roster | | | Before |
| 7/16/2026 | CUY | Marchan | Promoted to active roster | | | Before |
| 7/16/2026 | CUY | Scherzer | Promoted to active roster | | | Before |
| 7/16/2026 | CUY | Wesneski | Promoted to active roster | | | Before |
| 7/16/2026 | DSP | Farmer | Activated from Injured List | | | Before |
| 7/16/2026 | DSP | Schuemann | Demoted to reserve roster | | | Before |
| 7/16/2026 | HAV | Murphy,S | Demoted to reserve roster | | | Before |
| 7/16/2026 | NHP | Perkins,J | Activated from Injured List | | | Before |
| 7/16/2026 | NHP | Perkins,J | Demoted to reserve roster | | | Before |
| 7/16/2026 | PUE | Burnes | Promoted to active roster | | | Before |
| 7/16/2026 | PUE | Schmidt | Demoted to reserve roster | | | Before |
| 7/16/2026 | TOR | Keith | Activated from Injured List | | | Before |
| 7/16/2026 | TOR | Raley,B | Promoted to active roster | | | Before |
| 7/16/2026 | TOR | Stephenson,R | Demoted to reserve roster | | | Before |
| 7/16/2026 | TOR | Walter | Demoted to reserve roster | | | Before |
| 7/18/2026 | CGS | Barger | Acquired via trade | CLE | | After |
| 7/18/2026 | CGS | Baz | Traded away | CLE | | After |
| 7/18/2026 | CGS | Butler | Acquired via trade | CLE | | After |
| 7/18/2026 | CGS | Cease | Traded away | CLE | | After |
| 7/18/2026 | CGS | Diaz,Yan | Acquired via trade | CLE | | After |
| 7/18/2026 | CGS | Leahy | Acquired via trade | CLE | | After |
| 7/18/2026 | CGS | Rodriguez,En | Traded away | CLE | | After |
| 7/18/2026 | CGS | Senga | Acquired via trade | CLE | | After |
| 7/18/2026 | CGS | Sheehan | Acquired via trade | CLE | | After |
| 7/18/2026 | CLE | Barger | Traded away | CGS | | After |
| 7/18/2026 | CLE | Baz | Acquired via trade | CGS | | After |
| 7/18/2026 | CLE | Butler | Traded away | CGS | | After |
| 7/18/2026 | CLE | Cease | Acquired via trade | CGS | | After |
| 7/18/2026 | CLE | Diaz,Yan | Traded away | CGS | | After |
| 7/18/2026 | CLE | Leahy | Traded away | CGS | | After |
| 7/18/2026 | CLE | Rodriguez,En | Acquired via trade | CGS | | After |
| 7/18/2026 | CLE | Senga | Traded away | CGS | | After |
| 7/18/2026 | CLE | Sheehan | Traded away | CGS | | After |
| 7/18/2026 | CUY | Haggerty | Acquired via trade | TOR | | After |
| 7/18/2026 | CUY | Mears | Traded away | TOR | | After |
| 7/18/2026 | CUY | Sosa,E | Traded away | TOR | | After |
| 7/18/2026 | CUY | Webb,J | Acquired via trade | TOR | | After |
| 7/18/2026 | DSP | Raley,L | Acquired via trade | TOR | | After |
| 7/18/2026 | DSP | Romano | Traded away | TOR | | After |
| 7/18/2026 | DSP | Schneemann | Traded away | TOR | | After |
| 7/18/2026 | DSP | Soler | Acquired via trade | TOR | | After |
| 7/18/2026 | DSP | Stephenson,R | Acquired via trade | TOR | | After |
| 7/18/2026 | NDF | Bibee | Traded away | PBC | | After |
| 7/18/2026 | NDF | Bregman | Acquired via trade | PBC | | After |
| 7/18/2026 | NDF | Cronenworth | Traded away | PBC | | After |
| 7/18/2026 | NDF | Francis | Traded away | PBC | | After |
| 7/18/2026 | NDF | Mahle | Acquired via trade | PBC | | After |
| 7/18/2026 | NDF | Malloy | Traded away | PBC | | After |
| 7/18/2026 | NDF | Pederson | Traded away | PBC | | After |
| 7/18/2026 | NDF | Phillips,T | Traded away | PBC | | After |
| 7/18/2026 | NDF | Profar | Traded away | PBC | | After |
| 7/18/2026 | NDF | Santander | Acquired via trade | PBC | | After |
| 7/18/2026 | NDF | Wallner | Acquired via trade | PBC | | After |
| 7/18/2026 | PBC | Bibee | Acquired via trade | NDF | | After |
| 7/18/2026 | PBC | Bregman | Traded away | NDF | | After |
| 7/18/2026 | PBC | Cronenworth | Acquired via trade | NDF | | After |
| 7/18/2026 | PBC | Francis | Acquired via trade | NDF | | After |
| 7/18/2026 | PBC | Mahle | Traded away | NDF | | After |
| 7/18/2026 | PBC | Malloy | Acquired via trade | NDF | | After |
| 7/18/2026 | PBC | Pederson | Acquired via trade | NDF | | After |
| 7/18/2026 | PBC | Phillips,T | Acquired via trade | NDF | | After |
| 7/18/2026 | PBC | Profar | Acquired via trade | NDF | | After |
| 7/18/2026 | PBC | Santander | Traded away | NDF | | After |
| 7/18/2026 | PBC | Wallner | Traded away | NDF | | After |
| 7/18/2026 | TOR | Haggerty | Traded away | CUY | | After |
| 7/18/2026 | TOR | Mears | Acquired via trade | CUY | | After |
| 7/18/2026 | TOR | Raley,L | Traded away | DSP | | After |
| 7/18/2026 | TOR | Romano | Acquired via trade | DSP | | After |
| 7/18/2026 | TOR | Schneemann | Acquired via trade | DSP | | After |
| 7/18/2026 | TOR | Soler | Traded away | DSP | | After |
| 7/18/2026 | TOR | Sosa,E | Acquired via trade | CUY | | After |
| 7/18/2026 | TOR | Stephenson,R | Traded away | DSP | | After |
| 7/18/2026 | TOR | Webb,J | Traded away | CUY | | After |
| 7/19/2026 | CAP | Holmes,G | Activated from Injured List | | | Before |
| 7/19/2026 | CAP | Schwellenbach | Placed on Injured List | | 7/17/2026 | Before |
| 7/19/2026 | CED | Detmers | Demoted to reserve roster | | | Before |
| 7/19/2026 | CED | Dreyer | Demoted to reserve roster | | | Before |
| 7/19/2026 | CED | Hernandez,D | Promoted to active roster | | | Before |
| 7/19/2026 | CED | Minter | Promoted to active roster | | | Before |
| 7/19/2026 | DSP | Carlson | Demoted to reserve roster | | | Before |
| 7/19/2026 | DSP | Englert | Promoted to active roster | | | Before |
| 7/19/2026 | NDF | Beck,T | Promoted to active roster | | | Before |
| 7/19/2026 | NDF | Horwitz | Placed on Injured List | | 7/17/2026 | Before |
| 7/19/2026 | NDF | Kelly,Car | Activated from Injured List | | | Before |
| 7/19/2026 | NDF | Lopez,Ja | Promoted to active roster | | | Before |
| 7/19/2026 | NDF | Mahle | Promoted to active roster | | | Before |
| 7/19/2026 | NDF | Perez,M | Demoted to reserve roster | | | Before |
| 7/19/2026 | NDF | Sabrowski | Demoted to reserve roster | | | Before |
| 7/19/2026 | NHP | Chandler | Demoted to reserve roster | | | Before |
| 7/19/2026 | NHP | Maxwell | Promoted to active roster | | | Before |
| 7/19/2026 | PUE | Fulford | Demoted to reserve roster | | | Before |
| 7/19/2026 | PUE | Kinley | Promoted to active roster | | | Before |
| 7/19/2026 | PUE | Langeliers | Activated from Injured List | | | Before |
| 7/19/2026 | PUE | Lee,D | Demoted to reserve roster | | | Before |
| 7/22/2026 | CED | Casparius | Promoted to active roster | | | Before |
| 7/22/2026 | CED | Detmers | Promoted to active roster | | | Before |
| 7/22/2026 | CED | Dreyer | Promoted to active roster | | | Before |
| 7/22/2026 | CED | Fermin,Jose | Promoted to active roster | | | Before |
| 7/22/2026 | CED | Hernandez,D | Demoted to reserve roster | | | Before |
| 7/22/2026 | CED | Minter | Demoted to reserve roster | | | Before |
| 7/22/2026 | CED | Nunez,N | Placed on Injured List | | 7/22/2026 | Before |
| 7/22/2026 | CED | Yesavage | Demoted to reserve roster | | | Before |
| 7/22/2026 | CGS | Ferrer | Demoted to reserve roster | | | Before |
| 7/22/2026 | CGS | Hernaiz | Demoted to reserve roster | | | Before |
| 7/22/2026 | CGS | Hernaiz | Promoted to active roster | | | Before |
| 7/22/2026 | CGS | Lux | Demoted to reserve roster | | | Before |
| 7/22/2026 | CGS | Maldonado,M | Demoted to reserve roster | | | Before |
| 7/22/2026 | CGS | Montero,R | Demoted to reserve roster | | | Before |
| 7/22/2026 | CGS | Sheehan | Promoted to active roster | | | Before |
| 7/22/2026 | CLE | Baz | Promoted to active roster | | | Before |
| 7/22/2026 | CLE | Burns | Placed on Injured List | | 7/13/2026 | Before |
| 7/22/2026 | CLE | Laureano | Activated from Injured List | | | Before |
| 7/22/2026 | CLE | Osuna | Promoted to active roster | | | Before |
| 7/22/2026 | CLE | Sasaki | Activated from Injured List | | | Before |
| 7/22/2026 | CLE | Sugano | Activated from Injured List | | | Before |
| 7/22/2026 | CLE | Valera | Demoted to reserve roster | | | Before |
| 7/22/2026 | HOL | Gusto | Placed on Injured List | | 7/20/2026 | Before |
| 7/22/2026 | HOL | Ragans | Promoted to active roster | | | Before |
| 7/22/2026 | OLL | Bird | Placed on Injured List | | 7/14/2026 | Before |
| 7/22/2026 | OLL | Cano | Promoted to active roster | | | Before |
| 7/22/2026 | RMH | Civale | Promoted to active roster | | | Before |
| 7/22/2026 | RMH | Hernandez,H | Placed on Injured List | | 7/22/2026 | Before |
| 7/22/2026 | RMH | Lauer | Demoted to reserve roster | | | Before |
| 7/22/2026 | RMH | Walker,Jor | Promoted to active roster | | | Before |
| 7/22/2026 | TOR | Alvarez,Y | Demoted to reserve roster | | | Before |
| 7/22/2026 | TOR | Amaya,M | Demoted to reserve roster | | | Before |
| 7/22/2026 | TOR | Goodman | Promoted to active roster | | | Before |
| 7/22/2026 | TOR | Harvey | Promoted to active roster | | | Before |
| 7/22/2026 | TOR | Romano | Demoted to reserve roster | | | Before |
| 7/22/2026 | TOR | Romano | Promoted to active roster | | | Before |
| 7/25/2026 | AUR | Cantillo | Promoted to active roster | | | Before |
| 7/25/2026 | AUR | Ruiz,K | Demoted to reserve roster | | | Before |
| 7/25/2026 | CED | Detmers | Demoted to reserve roster | | | Before |
| 7/25/2026 | CED | Hernandez,D | Promoted to active roster | | | Before |
| 7/25/2026 | CED | Herrera,J | Demoted to reserve roster | | | Before |
| 7/25/2026 | CED | Jackson,L | Demoted to reserve roster | | | Before |
| 7/25/2026 | CED | Jones,J | Demoted to reserve roster | | | Before |
| 7/25/2026 | CED | McGuire | Promoted to active roster | | | Before |
| 7/25/2026 | CED | Minter | Promoted to active roster | | | Before |
| 7/25/2026 | CED | Tovar | Activated from Injured List | | | Before |
| 7/25/2026 | DSP | Darvish | Placed on Injured List | | 7/25/2026 | Before |
| 7/25/2026 | DSP | Stephenson,R | Promoted to active roster | | | Before |
| 7/25/2026 | PUE | Alvarez,A | Demoted to reserve roster | | | Before |
| 7/25/2026 | PUE | Bummer | Demoted to reserve roster | | | Before |
| 7/25/2026 | PUE | Enright | Promoted to active roster | | | Before |
| 7/25/2026 | PUE | Mlodzinski | Promoted to active roster | | | Before |
| 7/25/2026 | RMH | Gurriel,L | Activated from Injured List | | | Before |
| 7/25/2026 | RMH | Walker,Jor | Demoted to reserve roster | | | Before |
| 7/28/2026 | BOS | Stewart,S | Demoted to reserve roster | | | Before |
| 7/28/2026 | BOS | Vargas,I | Activated from Injured List | | | Before |
| 7/28/2026 | CED | Casparius | Demoted to reserve roster | | | Before |
| 7/28/2026 | CED | Detmers | Promoted to active roster | | | Before |
| 7/28/2026 | CED | Hernandez,D | Demoted to reserve roster | | | Before |
| 7/28/2026 | CED | Jackson,L | Promoted to active roster | | | Before |
| 7/28/2026 | CED | Kirby | Activated from Injured List | | | Before |
| 7/28/2026 | CED | Minter | Demoted to reserve roster | | | Before |
| 7/28/2026 | CUY | Alcantara,Sa | Activated from Injured List | | | Before |
| 7/28/2026 | CUY | Early | Promoted to active roster | | | Before |
| 7/28/2026 | CUY | France,T | Promoted to active roster | | | Before |
| 7/28/2026 | CUY | Funderburk | Demoted to reserve roster | | | Before |
| 7/28/2026 | CUY | Haggerty | Demoted to reserve roster | | | Before |
| 7/28/2026 | CUY | Loftin | Promoted to active roster | | | Before |
| 7/28/2026 | CUY | Palencia | Promoted to active roster | | | Before |
| 7/28/2026 | CUY | Scherzer | Demoted to reserve roster | | | Before |
| 7/28/2026 | CUY | Urias,R | Demoted to reserve roster | | | Before |
| 7/28/2026 | CUY | Verlander | Demoted to reserve roster | | | Before |
| 7/28/2026 | HAV | Ibanez | Demoted to reserve roster | | | Before |
| 7/28/2026 | HAV | Meyers | Activated from Injured List | | | Before |
| 7/28/2026 | HOL | Fermin,JM | Promoted to active roster | | | Before |
| 7/28/2026 | HOL | Ragans | Demoted to reserve roster | | | Before |
| 7/28/2026 | PUE | Beeks | Demoted to reserve roster | | | Before |
| 7/28/2026 | PUE | Feltner | Promoted to active roster | | | Before |
| 7/28/2026 | PUE | Lee,D | Promoted to active roster | | | Before |
| 7/28/2026 | PUE | Mlodzinski | Demoted to reserve roster | | | Before |
| 7/31/2026 | AUR | Bradish | Promoted to active roster | | | Before |
| 7/31/2026 | AUR | Cantillo | Placed on Injured List | | 7/29/2026 | Before |
| 7/31/2026 | CED | Cruz,F | Demoted to reserve roster | | | Before |
| 7/31/2026 | CED | Hays | Placed on Injured List | | 7/31/2026 | Before |
| 7/31/2026 | CED | Hernandez,D | Promoted to active roster | | | Before |
| 7/31/2026 | CED | Herrera,J | Promoted to active roster | | | Before |
| 7/31/2026 | CED | Minter | Promoted to active roster | | | Before |
| 7/31/2026 | CED | Romero | Demoted to reserve roster | | | Before |
| 7/31/2026 | HAV | Moreno | Placed on Injured List | | 7/30/2026 | Before |
| 7/31/2026 | HAV | Murphy,S | Promoted to active roster | | | Before |
| 7/31/2026 | HOL | Dubin | Promoted to active roster | | | Before |
| 7/31/2026 | HOL | Vodnik | Demoted to reserve roster | | | Before |
| 7/31/2026 | RMH | Cortes,C | Promoted to active roster | | | Before |
| 7/31/2026 | RMH | Torres | Placed on Injured List | | 7/30/2026 | Before |
| 7/31/2026 | RMH | Urias,L | Promoted to active roster | | | Before |
| 7/31/2026 | RMH | Wacha | Demoted to reserve roster | | | Before |
| 8/3/2026 | CED | Cruz,F | Promoted to active roster | | | Before |
| 8/3/2026 | CED | Hernandez,D | Demoted to reserve roster | | | Before |
| 8/3/2026 | CED | Pomeranz | Demoted to reserve roster | | | Before |
| 8/3/2026 | CED | Romero | Promoted to active roster | | | Before |
| 8/3/2026 | CGS | Hernaiz | Demoted to reserve roster | | | Before |
| 8/3/2026 | CGS | Lux | Promoted to active roster | | | Before |
| 8/3/2026 | DSP | Long | Activated from Injured List | | | Before |
| 8/3/2026 | DSP | Stephenson,R | Demoted to reserve roster | | | Before |
| 8/3/2026 | RMH | Civale | Demoted to reserve roster | | | Before |
| 8/3/2026 | RMH | Wacha | Promoted to active roster | | | Before |
| 8/6/2026 | BOS | Graceffo | Promoted to active roster | | | Before |
| 8/6/2026 | BOS | Horton | Placed on Injured List | | 8/6/2026 | Before |
| 8/6/2026 | CAP | Herrera,I | Placed on Injured List | | 7/29/2026 | Before |
| 8/6/2026 | CAP | Pages,P | Promoted to active roster | | | Before |
| 8/6/2026 | CLE | Carter | Activated from Injured List | | | Before |
| 8/6/2026 | CLE | Osuna | Demoted to reserve roster | | | Before |
| 8/6/2026 | DSP | Brieske | Promoted to active roster | | | Before |
| 8/6/2026 | DSP | Gil | Placed on Injured List | | 8/4/2026 | Before |
| 8/6/2026 | DSP | Knack | Promoted to active roster | | | Before |
| 8/6/2026 | DSP | McLean | Promoted to active roster | | | Before |
| 8/6/2026 | DSP | Morton | Demoted to reserve roster | | | Before |
| 8/6/2026 | DSP | Rea | Placed on Injured List | | 8/6/2026 | Before |
| 8/6/2026 | NDF | Horwitz | Activated from Injured List | | | Before |
| 8/6/2026 | NDF | Millas | Demoted to reserve roster | | | Before |
| 8/6/2026 | RMH | Bichette | Placed on Injured List | | 8/4/2026 | Before |
| 8/6/2026 | RMH | Lauer | Promoted to active roster | | | Before |
| 8/6/2026 | RMH | Mize | Demoted to reserve roster | | | Before |
| 8/6/2026 | RMH | Walls | Promoted to active roster | | | Before |
| 8/9/2026 | AUR | Bradish | Demoted to reserve roster | | | Before |
| 8/9/2026 | AUR | Cantillo | Activated from Injured List | | | Before |
| 8/9/2026 | CAP | Koss | Promoted to active roster | | | Before |
| 8/9/2026 | CAP | Neto | Placed on Injured List | | 8/9/2026 | Before |
| 8/9/2026 | HOL | Gusto | Activated from Injured List | | | Before |
| 8/9/2026 | HOL | Ray | Demoted to reserve roster | | | Before |
| 8/9/2026 | NHP | Baty | Demoted to reserve roster | | | Before |
| 8/9/2026 | NHP | Caissie | Promoted to active roster | | | Before |
| 8/9/2026 | NHP | Dezenzo | Demoted to reserve roster | | | Before |
| 8/9/2026 | NHP | Hamilton,I | Demoted to reserve roster | | | Before |
| 8/9/2026 | NHP | McDermott | Promoted to active roster | | | Before |
| 8/9/2026 | OLL | Eaton | Promoted to active roster | | | Before |
| 8/9/2026 | OLL | House | Placed on Injured List | | 8/8/2026 | Before |
| 8/9/2026 | RMH | Cortes,C | Demoted to reserve roster | | | Before |
| 8/9/2026 | RMH | Flaherty | Demoted to reserve roster | | | Before |
| 8/9/2026 | RMH | Hernandez,H | Activated from Injured List | | | Before |
| 8/9/2026 | RMH | Mize | Promoted to active roster | | | Before |
| 8/9/2026 | TOR | Bergert | Promoted to active roster | | | Before |
| 8/9/2026 | TOR | Evans | Demoted to reserve roster | | | Before |
| 8/9/2026 | TOR | Romano | Demoted to reserve roster | | | Before |
| 8/9/2026 | TOR | Schneemann | Activated from Injured List | | | Before |
| 8/12/2026 | AUR | Lee,B | Demoted to reserve roster | | | Before |
| 8/12/2026 | AUR | Sanoja | Promoted to active roster | | | Before |
| 8/12/2026 | CED | Detmers | Demoted to reserve roster | | | Before |
| 8/12/2026 | CED | Fermin,Jose | Placed on Injured List | | 8/12/2026 | Before |
| 8/12/2026 | CED | Minter | Demoted to reserve roster | | | Before |
| 8/12/2026 | CED | Nunez,N | Activated from Injured List | | | Before |
| 8/12/2026 | CED | Palacios,R | Promoted to active roster | | | Before |
| 8/12/2026 | CED | Pomeranz | Promoted to active roster | | | Before |
| 8/12/2026 | HAV | Ibanez | Promoted to active roster | | | Before |
| 8/12/2026 | HAV | Pena | Placed on Injured List | | 8/10/2026 | Before |
| 8/12/2026 | NHP | Chandler | Promoted to active roster | | | Before |
| 8/12/2026 | OLL | Bird | Activated from Injured List | | | Before |
| 8/12/2026 | OLL | Klein | Demoted to reserve roster | | | Before |
| 8/12/2026 | RMH | Flaherty | Promoted to active roster | | | Before |
| 8/12/2026 | RMH | Junk | Demoted to reserve roster | | | Before |
| 8/12/2026 | RMH | Torres | Activated from Injured List | | | Before |
| 8/12/2026 | RMH | Urias,L | Demoted to reserve roster | | | Before |
| 8/15/2026 | CED | Casparius | Promoted to active roster | | | Before |
| 8/15/2026 | CED | Detmers | Promoted to active roster | | | Before |
| 8/15/2026 | CED | Nunez,N | Demoted to reserve roster | | | Before |
| 8/15/2026 | CED | Perez,E | Demoted to reserve roster | | | Before |
| 8/15/2026 | CLE | Allard | Demoted to reserve roster | | | Before |
| 8/15/2026 | CLE | Kim,Ha | Promoted to active roster | | | Before |
| 8/15/2026 | NHP | Acuna,R | Demoted to reserve roster | | | Before |
| 8/15/2026 | NHP | Chandler | Demoted to reserve roster | | | Before |
| 8/15/2026 | NHP | DeLauter | Promoted to active roster | | | Before |
| 8/15/2026 | NHP | Hamilton,I | Promoted to active roster | | | Before |
| 8/15/2026 | PEI | Duran,E | Promoted to active roster | | | Before |
| 8/15/2026 | PEI | Gimenez | Placed on Injured List | | 8/10/2026 | Before |
| 8/15/2026 | PUE | Blubaugh | Promoted to active roster | | | Before |
| 8/15/2026 | PUE | Flexen | Demoted to reserve roster | | | Before |
| 8/15/2026 | RMH | Junk | Promoted to active roster | | | Before |
| 8/15/2026 | RMH | Wacha | Demoted to reserve roster | | | Before |
| 8/18/2026 | AUR | Ruiz,K | Promoted to active roster | | | Before |
| 8/18/2026 | AUR | Wynns | Demoted to reserve roster | | | Before |
| 8/18/2026 | BOS | Graceffo | Demoted to reserve roster | | | Before |
| 8/18/2026 | BOS | Horton | Activated from Injured List | | | Before |
| 8/18/2026 | CAP | Lee,J | Promoted to active roster | | | Before |
| 8/18/2026 | CAP | Tucker | Placed on Injured List | | 8/16/2026 | Before |
| 8/18/2026 | NHP | Dezenzo | Promoted to active roster | | | Before |
| 8/18/2026 | NHP | Hamilton,I | Demoted to reserve roster | | | Before |
| 8/18/2026 | RMH | Bichette | Activated from Injured List | | | Before |
| 8/18/2026 | RMH | Lauer | Demoted to reserve roster | | | Before |
| 8/18/2026 | RMH | Wacha | Promoted to active roster | | | Before |
| 8/18/2026 | RMH | Walls | Demoted to reserve roster | | | Before |
| 8/21/2026 | AUR | Ortiz,L | Demoted to reserve roster | | | Before |
| 8/21/2026 | AUR | Ruiz,K | Promoted to active roster | | | Before |
| 8/21/2026 | AUR | Waldrep | Promoted to active roster | | | Before |
| 8/21/2026 | AUR | Wynns | Demoted to reserve roster | | | Before |
| 8/21/2026 | DSP | Boyle | Demoted to reserve roster | | | Before |
| 8/21/2026 | DSP | Darvish | Activated from Injured List | | | Before |
| 8/21/2026 | DUR | Hill,J | Promoted to active roster | | | Before |
| 8/21/2026 | DUR | Matz | Placed on Injured List | | 8/21/2026 | Before |
| 8/21/2026 | NDF | McDonald | Promoted to active roster | | | Before |
| 8/21/2026 | NDF | Winn,C | Demoted to reserve roster | | | Before |
| 8/21/2026 | RMH | Lauer | Promoted to active roster | | | Before |
| 8/21/2026 | RMH | Mize | Demoted to reserve roster | | | Before |
| 8/24/2026 | AUR | Bautista | Demoted to reserve roster | | | Before |
| 8/24/2026 | AUR | Peguero,J | Promoted to active roster | | | Before |
| 8/24/2026 | CAP | Holmes,G | Demoted to reserve roster | | | Before |
| 8/24/2026 | CAP | Koss | Demoted to reserve roster | | | Before |
| 8/24/2026 | CAP | Neto | Activated from Injured List | | | Before |
| 8/24/2026 | CAP | Schwellenbach | Activated from Injured List | | | Before |
| 8/24/2026 | CED | Cruz,F | Demoted to reserve roster | | | Before |
| 8/24/2026 | CED | Detmers | Demoted to reserve roster | | | Before |
| 8/24/2026 | CED | Lawrence,J | Promoted to active roster | | | Before |
| 8/24/2026 | CED | Minter | Promoted to active roster | | | Before |
| 8/24/2026 | DSP | Brieske | Demoted to reserve roster | | | Before |
| 8/24/2026 | DSP | Rea | Activated from Injured List | | | Before |
| 8/24/2026 | NHP | Baty | Promoted to active roster | | | Before |
| 8/24/2026 | NHP | Caissie | Demoted to reserve roster | | | Before |
| 8/24/2026 | PUE | Avila | Promoted to active roster | | | Before |
| 8/24/2026 | PUE | Castellanos | Demoted to reserve roster | | | Before |
| 8/24/2026 | PUE | Castellanos | Promoted to active roster | | | Before |
| 8/24/2026 | PUE | Castellanos | Demoted to reserve roster | | | Before |
| 8/24/2026 | PUE | Henriquez,R | Demoted to reserve roster | | | Before |
| 8/24/2026 | PUE | Martin,A | Promoted to active roster | | | Before |
| 8/24/2026 | RMH | Flaherty | Demoted to reserve roster | | | Before |
| 8/24/2026 | RMH | Mize | Promoted to active roster | | | Before |
| 8/27/2026 | AUR | Lee,B | Promoted to active roster | | | Before |
| 8/27/2026 | AUR | Perkins,B | Demoted to reserve roster | | | Before |
| 8/27/2026 | CAP | Herrera,I | Activated from Injured List | | | Before |
| 8/27/2026 | CAP | Pages,P | Demoted to reserve roster | | | Before |
| 8/27/2026 | CGS | Ferrer | Promoted to active roster | | | Before |
| 8/27/2026 | CGS | Sheehan | Demoted to reserve roster | | | Before |
| 8/27/2026 | CUY | Early | Demoted to reserve roster | | | Before |
| 8/27/2026 | CUY | Funderburk | Promoted to active roster | | | Before |
| 8/27/2026 | CUY | Melton,T | Promoted to active roster | | | Before |
| 8/27/2026 | CUY | Svanson | Demoted to reserve roster | | | Before |
| 8/27/2026 | CUY | Verlander | Promoted to active roster | | | Before |
| 8/27/2026 | CUY | Wesneski | Demoted to reserve roster | | | Before |
| 8/27/2026 | DSP | Gil | Activated from Injured List | | | Before |
| 8/27/2026 | DSP | Taillon | Demoted to reserve roster | | | Before |
| 8/27/2026 | HAV | Little,L | Promoted to active roster | | | Before |
| 8/27/2026 | HAV | Morgan,D | Placed on Injured List | | 8/26/2026 | Before |
| 8/27/2026 | HAV | Slaten | Promoted to active roster | | | Before |
| 8/27/2026 | HAV | Suarez,Ra | Placed on Injured List | | 8/26/2026 | Before |
| 8/27/2026 | PUE | Burnes | Demoted to reserve roster | | | Before |
| 8/27/2026 | PUE | Sproat | Promoted to active roster | | | Before |
| 8/27/2026 | RMH | Cortes,C | Promoted to active roster | | | Before |
| 8/27/2026 | RMH | Flaherty | Promoted to active roster | | | Before |
| 8/27/2026 | RMH | Johnson,B | Demoted to reserve roster | | | Before |
| 8/27/2026 | RMH | Mize | Demoted to reserve roster | | | Before |
| 8/27/2026 | TOR | Amaya,M | Promoted to active roster | | | Before |
| 8/27/2026 | TOR | Harvey | Demoted to reserve roster | | | Before |
| 8/27/2026 | TOR | Keaschall | Demoted to reserve roster | | | Before |
| 8/27/2026 | TOR | Miller,E | Promoted to active roster | | | Before |
| 8/30/2026 | DSP | McLean | Placed on Injured List | | 8/29/2026 | Before |
| 8/30/2026 | DSP | Taillon | Promoted to active roster | | | Before |
| 8/30/2026 | HOL | Rodriguez,R | Demoted to reserve roster | | | Before |
| 8/30/2026 | HOL | Vargas,C | Promoted to active roster | | | Before |
| 9/2/2026 | BOS | Graceffo | Promoted to active roster | | | Before |
| 9/2/2026 | BOS | Mangum | Placed on Injured List | | 9/2/2026 | Before |
| 9/2/2026 | BOS | Rasmussen | Placed on Injured List | | 9/2/2026 | Before |
| 9/2/2026 | BOS | Robles | Promoted to active roster | | | Before |
| 9/2/2026 | DSP | Knack | Demoted to reserve roster | | | Before |
| 9/2/2026 | DSP | Montgomery,C | Demoted to reserve roster | | | Before |
| 9/2/2026 | DSP | Schuemann | Promoted to active roster | | | Before |
| 9/2/2026 | DSP | Stephenson,R | Promoted to active roster | | | Before |
| 9/2/2026 | HOL | Ray | Promoted to active roster | | | Before |
| 9/2/2026 | HOL | Woodruff | Demoted to reserve roster | | | Before |
| 9/2/2026 | NHP | Acuna,R | Promoted to active roster | | | Before |
| 9/2/2026 | NHP | Alcantara,K | Promoted to active roster | | | Before |
| 9/2/2026 | NHP | Arrighetti | Demoted to reserve roster | | | Before |
| 9/2/2026 | NHP | Ballesteros | Promoted to active roster | | | Before |
| 9/2/2026 | NHP | Maxwell | Demoted to reserve roster | | | Before |
| 9/2/2026 | NHP | Mey | Demoted to reserve roster | | | Before |
| 9/2/2026 | PEI | Peterson | Placed on Injured List | | 8/30/2026 | Before |
| 9/2/2026 | PEI | Wells,T | Promoted to active roster | | | Before |
| 9/2/2026 | RMH | Junk | Demoted to reserve roster | | | Before |
| 9/2/2026 | RMH | Mize | Promoted to active roster | | | Before |
| 9/2/2026 | WTB | Canning | Demoted to reserve roster | | | Before |
| 9/2/2026 | WTB | Jarvis | Demoted to reserve roster | | | Before |
| 9/2/2026 | WTB | Sweeney | Promoted to active roster | | | Before |
| 9/2/2026 | WTB | Verdugo | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Alvarado,J | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Ashby | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Bender | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Eovaldi | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Gonzalez,R | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Hall | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Helsley | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Herrera,I | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Holmes,G | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Koss | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Langford | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Mastrobuoni | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Neto | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Paddack | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Pages,P | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Pfaadt | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Refsnyder | Demoted to reserve roster | | | Before |
| 9/5/2026 | CAP | Schwellenbach | Placed on Injured List | | 9/5/2026 | Before |
| 9/5/2026 | CAP | Thomas,Col | Promoted to active roster | | | Before |
| 9/5/2026 | CAP | Yamamoto | Demoted to reserve roster | | | Before |
| 9/5/2026 | CED | Fermin,Jose | Activated from Injured List | | | Before |
| 9/5/2026 | CED | Hays | Activated from Injured List | | | Before |
| 9/5/2026 | CED | Iglesias,J | Demoted to reserve roster | | | Before |
| 9/5/2026 | CED | McGuire | Demoted to reserve roster | | | Before |
| 9/5/2026 | CED | Monasterio | Promoted to active roster | | | Before |
| 9/5/2026 | CED | Palacios,R | Demoted to reserve roster | | | Before |
| 9/5/2026 | CGS | Montero,R | Promoted to active roster | | | Before |
| 9/5/2026 | CGS | Rogers,Tr | Placed on Injured List | | 9/4/2026 | Before |
| 9/5/2026 | DSP | Boyle | Promoted to active roster | | | Before |
| 9/5/2026 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 9/5/2026 | DSP | Kopech | Promoted to active roster | | | Before |
| 9/5/2026 | DSP | Long | Demoted to reserve roster | | | Before |
| 9/5/2026 | HAV | Ibanez | Demoted to reserve roster | | | Before |
| 9/5/2026 | HAV | Moreno | Activated from Injured List | | | Before |
| 9/5/2026 | HAV | Murphy,S | Demoted to reserve roster | | | Before |
| 9/5/2026 | HAV | Pena | Activated from Injured List | | | Before |
| 9/5/2026 | HOL | Allen,N | Promoted to active roster | | | Before |
| 9/5/2026 | HOL | Contreras,WJ | Demoted to reserve roster | | | Before |
| 9/5/2026 | HOL | Donovan | Demoted to reserve roster | | | Before |
| 9/5/2026 | HOL | Maile | Promoted to active roster | | | Before |
| 9/5/2026 | HOL | Ragans | Promoted to active roster | | | Before |
| 9/5/2026 | HOL | Skubal | Demoted to reserve roster | | | Before |
| 9/5/2026 | PEI | Gonzalez,W | Demoted to reserve roster | | | Before |
| 9/5/2026 | PEI | Rojas,Joh | Promoted to active roster | | | Before |
| 9/5/2026 | PEI | Santos | Promoted to active roster | | | Before |
| 9/5/2026 | PEI | Schlittler | Demoted to reserve roster | | | Before |
| 9/5/2026 | PEI | Smith-Shawver | Promoted to active roster | | | Before |
| 9/5/2026 | PEI | Varsho | Demoted to reserve roster | | | Before |
| 9/5/2026 | PUE | Clarke,T | Demoted to reserve roster | | | Before |
| 9/5/2026 | PUE | Henriquez,R | Promoted to active roster | | | Before |
| 9/5/2026 | PUE | Schmitt | Demoted to reserve roster | | | Before |
| 9/5/2026 | PUE | Sogard | Promoted to active roster | | | Before |
| 9/5/2026 | TOR | Evans | Promoted to active roster | | | Before |
| 9/5/2026 | TOR | Greene,H | Demoted to reserve roster | | | Before |
| 9/8/2026 | CED | Hays | Placed on Injured List | | 9/8/2026 | Before |
| 9/8/2026 | CED | Jones,J | Promoted to active roster | | | Before |
| 9/8/2026 | DSP | Bart | Demoted to reserve roster | | | Before |
| 9/8/2026 | DSP | Bart | Promoted to active roster | | | Before |
| 9/8/2026 | DSP | Boyle | Demoted to reserve roster | | | Before |
| 9/8/2026 | DSP | Long | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Aranda | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Armstrong | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Ashcraft,B | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Barco | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Bliss | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Correa | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Crews | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Davis,H | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Freeman,T | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Karros | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Lee,C | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Lile | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Lockridge | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Mateo | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Matz | Activated from Injured List | | | Before |
| 9/8/2026 | DUR | Mitchell | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Muncy,Max | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Myers,T | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Olson,M | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Pivetta | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Rafaela | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Smith,P | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Stephenson,T | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Turang | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Woo | Demoted to reserve roster | | | Before |
| 9/8/2026 | DUR | Woods Richardso | Placed on Injured List | | 9/1/2026 | Before |
| 9/8/2026 | DUR | Wrobleski | Promoted to active roster | | | Before |
| 9/8/2026 | DUR | Yelich | Demoted to reserve roster | | | Before |
| 9/8/2026 | HOL | Fried | Demoted to reserve roster | | | Before |
| 9/8/2026 | HOL | Hernandez,E | Promoted to active roster | | | Before |
| 9/8/2026 | HOL | Kochanowicz | Promoted to active roster | | | Before |
| 9/8/2026 | HOL | Munoz,A | Demoted to reserve roster | | | Before |
| 9/8/2026 | HOL | Rogers,Ty | Demoted to reserve roster | | | Before |
| 9/8/2026 | HOL | Vodnik | Promoted to active roster | | | Before |
| 9/8/2026 | NDF | Kayfus | Promoted to active roster | | | Before |
| 9/8/2026 | NDF | Kershaw | Demoted to reserve roster | | | Before |
| 9/8/2026 | NDF | Perez,M | Promoted to active roster | | | Before |
| 9/8/2026 | NDF | Seager | Demoted to reserve roster | | | Before |
| 9/8/2026 | NHP | Harris,Ho | Demoted to reserve roster | | | Before |
| 9/8/2026 | NHP | McDermott | Demoted to reserve roster | | | Before |
| 9/8/2026 | PUE | Blubaugh | Placed on Injured List | | 9/7/2026 | Before |
| 9/8/2026 | PUE | Fulford | Promoted to active roster | | | Before |
| 9/8/2026 | PUE | Langeliers | Placed on Injured List | | 9/4/2026 | Before |
| 9/8/2026 | PUE | Mlodzinski | Promoted to active roster | | | Before |
| 9/8/2026 | RMH | Flaherty | Demoted to reserve roster | | | Before |
| 9/8/2026 | RMH | Junk | Promoted to active roster | | | Before |
| 9/11/2026 | AUR | Bradish | Promoted to active roster | | | Before |
| 9/11/2026 | AUR | Waldrep | Demoted to reserve roster | | | Before |
| 9/11/2026 | CAP | Caminero | Demoted to reserve roster | | | Before |
| 9/11/2026 | CAP | Cowser | Promoted to active roster | | | Before |
| 9/11/2026 | CED | Cook | Promoted to active roster | | | Before |
| 9/11/2026 | CED | Jackson,L | Demoted to reserve roster | | | Before |
| 9/11/2026 | CED | Jones,J | Demoted to reserve roster | | | Before |
| 9/11/2026 | CED | Nunez,N | Promoted to active roster | | | Before |
| 9/11/2026 | CGS | Estrada,J | Promoted to active roster | | | Before |
| 9/11/2026 | CGS | Leahy | Demoted to reserve roster | | | Before |
| 9/11/2026 | DSP | Kiner-Falefa | Demoted to reserve roster | | | Before |
| 9/11/2026 | DSP | White,E | Promoted to active roster | | | Before |
| 9/11/2026 | HOL | Grisham | Demoted to reserve roster | | | Before |
| 9/11/2026 | HOL | Polanco | Demoted to reserve roster | | | Before |
| 9/11/2026 | NHP | Acuna,R | Demoted to reserve roster | | | Before |
| 9/11/2026 | NHP | Cavalli | Demoted to reserve roster | | | Before |
| 9/11/2026 | PUE | Feltner | Demoted to reserve roster | | | Before |
| 9/11/2026 | PUE | Fitts | Promoted to active roster | | | Before |
| 9/11/2026 | PUE | Flexen | Promoted to active roster | | | Before |
| 9/11/2026 | PUE | Sproat | Demoted to reserve roster | | | Before |
| 9/11/2026 | RMH | Flaherty | Promoted to active roster | | | Before |
| 9/11/2026 | RMH | Junk | Demoted to reserve roster | | | Before |