| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 3/27/2026 | AUR | Johnston | Traded away | RMH | | After |
| 3/27/2026 | AUR | Wynns | Acquired via trade | RMH | | After |
| 3/27/2026 | RMH | Johnston | Acquired via trade | AUR | | After |
| 3/27/2026 | RMH | Wynns | Traded away | AUR | | After |
| 4/8/2026 | CED | Cruz,F | Placed on Injured List | | 4/7/2026 | Before |
| 4/8/2026 | CED | Detmers | Promoted to active roster | | | Before |
| 4/8/2026 | NHP | Cavalli | Demoted to reserve roster | | | Before |
| 4/8/2026 | NHP | Curtiss | Promoted to active roster | | | Before |
| 4/8/2026 | NHP | Spence | Demoted to reserve roster | | | Before |
| 4/8/2026 | NHP | Strowd | Promoted to active roster | | | Before |
| 4/8/2026 | PUE | Castellanos | Promoted to active roster | | | Before |
| 4/8/2026 | PUE | Lewis | Placed on Injured List | | 4/6/2026 | Before |
| 4/8/2026 | PUE | Sproat | Promoted to active roster | | | Before |
| 4/8/2026 | PUE | Vasil | Placed on Injured List | | 4/8/2026 | Before |
| 4/11/2026 | NHP | Arrighetti | Promoted to active roster | | | Before |
| 4/11/2026 | NHP | Curtiss | Demoted to reserve roster | | | Before |
| 4/11/2026 | NHP | Spence | Promoted to active roster | | | Before |
| 4/11/2026 | NHP | Strowd | Demoted to reserve roster | | | Before |
| 4/14/2026 | CAP | Ashby | Placed on Injured List | | 4/13/2026 | Before |
| 4/14/2026 | CAP | Holmes,G | Promoted to active roster | | | Before |
| 4/14/2026 | CAP | Schwellenbach | Placed on Injured List | | 4/13/2026 | Before |
| 4/14/2026 | CAP | Varland | Promoted to active roster | | | Before |
| 4/14/2026 | DSP | Darvish | Promoted to active roster | | | Before |
| 4/14/2026 | DSP | McLean | Demoted to reserve roster | | | Before |
| 4/17/2026 | CAP | Paddack | Promoted to active roster | | | Before |
| 4/17/2026 | CAP | Pfaadt | Promoted to active roster | | | Before |
| 4/17/2026 | CAP | Soriano,J | Placed on Injured List | | 4/15/2026 | Before |
| 4/17/2026 | CAP | Yamamoto | Placed on Injured List | | 4/16/2026 | Before |
| 4/17/2026 | RMH | Civale | Promoted to active roster | | | Before |
| 4/17/2026 | RMH | Lauer | Placed on Injured List | | 4/15/2026 | Before |
| 4/20/2026 | CLE | Sheehan | Promoted to active roster | | | Before |
| 4/20/2026 | CLE | Sugano | Demoted to reserve roster | | | Before |
| 4/20/2026 | CUY | Loftin | Promoted to active roster | | | Before |
| 4/20/2026 | CUY | Westburg | Placed on Injured List | | 4/18/2026 | Before |
| 4/20/2026 | OLL | Fedde | Placed on Injured List | | 4/20/2026 | Before |
| 4/20/2026 | OLL | Houck | Promoted to active roster | | | Before |
| 4/20/2026 | PBC | Bregman | Placed on Injured List | | 4/18/2026 | Before |
| 4/20/2026 | PBC | Tena | Promoted to active roster | | | Before |
| 4/20/2026 | RMH | Civale | Promoted to active roster | | | Before |
| 4/23/2026 | BOS | Stewart,S | Promoted to active roster | | | Before |
| 4/23/2026 | BOS | Vargas,I | Placed on Injured List | | 4/22/2026 | Before |
| 4/23/2026 | CGS | Flaherty | Traded away | RMH | | After |
| 4/23/2026 | CGS | Flaherty | Acquired via trade | RMH | | After |
| 4/23/2026 | CGS | Rogers,Tr | Traded away | RMH | | After |
| 4/23/2026 | CGS | Rogers,Tr | Acquired via trade | RMH | | After |
| 4/23/2026 | CGS | Walker,Jor | Traded away | RMH | | After |
| 4/23/2026 | CGS | Walker,Jor | Acquired via trade | RMH | | After |
| 4/23/2026 | PUE | Burleson | Placed on Injured List | | 4/21/2026 | Before |
| 4/23/2026 | PUE | Lewis | Activated from Injured List | | | Before |
| 4/23/2026 | PUE | Sproat | Demoted to reserve roster | | | Before |
| 4/23/2026 | PUE | Vasil | Activated from Injured List | | | Before |
| 4/23/2026 | RMH | Call | Placed on Injured List | | 4/22/2026 | Before |
| 4/23/2026 | RMH | Johnson,B | Promoted to active roster | | | Before |
| 4/23/2026 | RMH | Flaherty | Traded away | CGS | | After |
| 4/23/2026 | RMH | Flaherty | Acquired via trade | CGS | | After |
| 4/23/2026 | RMH | Rogers,Tr | Traded away | CGS | | After |
| 4/23/2026 | RMH | Rogers,Tr | Acquired via trade | CGS | | After |
| 4/23/2026 | RMH | Walker,Jor | Traded away | CGS | | After |
| 4/23/2026 | RMH | Walker,Jor | Acquired via trade | CGS | | After |
| 4/23/2026 | WTB | Contreras,R | Demoted to reserve roster | | | Before |
| 4/23/2026 | WTB | Jarvis | Promoted to active roster | | | Before |
| 4/26/2026 | CAP | Ashby | Activated from Injured List | | | Before |
| 4/26/2026 | CAP | Hall | Demoted to reserve roster | | | Before |
| 4/26/2026 | CAP | Paddack | Demoted to reserve roster | | | Before |
| 4/26/2026 | CAP | Yamamoto | Activated from Injured List | | | Before |
| 4/26/2026 | CED | Cruz,F | Activated from Injured List | | | Before |
| 4/26/2026 | CED | Detmers | Demoted to reserve roster | | | Before |
| 4/29/2026 | BOS | Muncy,Max | Traded away | NHP | | After |
| 4/29/2026 | BOS | Muncy,MP | Acquired via trade | NHP | | After |
| 4/29/2026 | NHP | Muncy,Max | Acquired via trade | BOS | | After |
| 4/29/2026 | NHP | Muncy,MP | Traded away | BOS | | After |
| 5/2/2026 | AUR | Lee,B | Promoted to active roster | | | Before |
| 5/2/2026 | AUR | Smith,Do | Placed on Injured List | | 5/2/2026 | Before |
| 5/2/2026 | CAP | Holmes,G | Demoted to reserve roster | | | Before |
| 5/2/2026 | CAP | Soriano,J | Activated from Injured List | | | Before |
| 5/2/2026 | RMH | Call | Activated from Injured List | | | Before |
| 5/2/2026 | RMH | Civale | Demoted to reserve roster | | | Before |
| 5/2/2026 | RMH | Johnson,B | Demoted to reserve roster | | | Before |
| 5/2/2026 | RMH | Lauer | Activated from Injured List | | | Before |