| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/8/2026 | CED | Cruz,F | Placed on Injured List | | 4/7/2026 | Before |
| 4/8/2026 | CED | Detmers | Promoted to active roster | | | Before |
| 4/8/2026 | NHP | Cavalli | Demoted to reserve roster | | | Before |
| 4/8/2026 | NHP | Curtiss | Promoted to active roster | | | Before |
| 4/8/2026 | NHP | Spence | Demoted to reserve roster | | | Before |
| 4/8/2026 | NHP | Strowd | Promoted to active roster | | | Before |
| 4/11/2026 | NHP | Arrighetti | Promoted to active roster | | | Before |
| 4/11/2026 | NHP | Curtiss | Demoted to reserve roster | | | Before |
| 4/11/2026 | NHP | Spence | Promoted to active roster | | | Before |
| 4/11/2026 | NHP | Strowd | Demoted to reserve roster | | | Before |
| 4/14/2026 | DSP | Darvish | Promoted to active roster | | | Before |
| 4/14/2026 | DSP | McLean | Demoted to reserve roster | | | Before |
| 4/23/2026 | BOS | Stewart,S | Promoted to active roster | | | Before |
| 4/23/2026 | BOS | Vargas,I | Placed on Injured List | | 4/22/2026 | Before |
| 4/23/2026 | WTB | Contreras,R | Demoted to reserve roster | | | Before |
| 4/23/2026 | WTB | Jarvis | Promoted to active roster | | | Before |
| 4/26/2026 | CED | Cruz,F | Activated from Injured List | | | Before |
| 4/26/2026 | CED | Detmers | Demoted to reserve roster | | | Before |
| 4/29/2026 | BOS | Muncy,Max | Traded away | NHP | | After |
| 4/29/2026 | BOS | Muncy,MP | Acquired via trade | NHP | | After |
| 4/29/2026 | NHP | Muncy,Max | Acquired via trade | BOS | | After |
| 4/29/2026 | NHP | Muncy,MP | Traded away | BOS | | After |
| 5/5/2026 | BOS | Stewart,S | Demoted to reserve roster | | | Before |
| 5/5/2026 | BOS | Vargas,I | Activated from Injured List | | | Before |
| 5/5/2026 | NHP | Cavalli | Promoted to active roster | | | Before |
| 5/5/2026 | NHP | Wheeler | Placed on Injured List | | 5/3/2026 | Before |
| 5/5/2026 | TOR | Alvarez,Y | Demoted to reserve roster | | | Before |
| 5/5/2026 | TOR | Brown,H | Placed on Injured List | | 5/1/2026 | Before |
| 5/5/2026 | TOR | Evans | Promoted to active roster | | | Before |
| 5/5/2026 | TOR | Garrett | Promoted to active roster | | | Before |
| 5/5/2026 | TOR | Jensen | Promoted to active roster | | | Before |
| 5/5/2026 | TOR | Raley,L | Demoted to reserve roster | | | Before |
| 5/8/2026 | TOR | Bergert | Demoted to reserve roster | | | Before |
| 5/8/2026 | TOR | Keith | Placed on Injured List | | 5/7/2026 | Before |
| 5/8/2026 | TOR | Miller,Br | Promoted to active roster | | | Before |
| 5/8/2026 | TOR | Raley,L | Promoted to active roster | | | Before |
| 5/11/2026 | DSP | Boyle | Demoted to reserve roster | | | Before |
| 5/11/2026 | DSP | Carlson | Promoted to active roster | | | Before |
| 5/13/2026 | HAV | Banks | Acquired via trade | CLE | | After |
| 5/13/2026 | HAV | Henriquez,E | Traded away | CLE | | After |
| 5/14/2026 | BOS | Graceffo | Promoted to active roster | | | Before |
| 5/14/2026 | BOS | Hanifee | Promoted to active roster | | | Before |
| 5/14/2026 | BOS | Horton | Placed on Injured List | | 5/14/2026 | Before |
| 5/14/2026 | BOS | Taylor,G | Placed on Injured List | | 5/11/2026 | Before |
| 5/14/2026 | HAV | Sale | Placed on Injured List | | 5/11/2026 | Before |
| 5/14/2026 | SPR | Abbott | Placed on Injured List | | 5/6/2026 | Before |
| 5/14/2026 | SPR | Jobe | Promoted to active roster | | | Before |
| 5/16/2026 | NHP | Acuna,R | Acquired via trade | CUY | | After |
| 5/16/2026 | NHP | Caissie | Acquired via trade | CUY | | After |
| 5/16/2026 | NHP | Chandler | Acquired via trade | CUY | | After |
| 5/16/2026 | NHP | deGrom | Traded away | CUY | | After |
| 5/16/2026 | NHP | Springer | Traded away | CUY | | After |
| 5/16/2026 | NHP | Svanson | Traded away | CUY | | After |
| 5/17/2026 | NHP | Curtiss | Promoted to active roster | | | Before |
| 5/17/2026 | NHP | Strowd | Promoted to active roster | | | Before |
| 5/17/2026 | PEI | Higashioka | Placed on Injured List | | 5/12/2026 | Before |
| 5/17/2026 | PEI | Stallings | Promoted to active roster | | | Before |