| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/8/2025 | AUR | Conine | Promoted to active roster | | | Before |
| 4/8/2025 | AUR | Larnach | Placed on Injured List | | 4/6/2025 | Before |
| 4/8/2025 | CGS | Buxton | Placed on Injured List | | 4/7/2025 | Before |
| 4/8/2025 | CGS | Trout | Promoted to active roster | | | Before |
| 4/8/2025 | SPR | Candelario | Placed on Injured List | | 4/6/2025 | Before |
| 4/8/2025 | SPR | Flores | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Amaya,M | Placed on Injured List | | 4/7/2025 | Before |
| 4/8/2025 | TOR | Bednar | Demoted to reserve roster | | | Before |
| 4/8/2025 | TOR | Bednar | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Bednar | Demoted to reserve roster | | | Before |
| 4/8/2025 | TOR | Betts | Placed on Injured List | | 4/7/2025 | Before |
| 4/8/2025 | TOR | Goodman | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Greene,H | Placed on Injured List | | 4/8/2025 | Before |
| 4/8/2025 | TOR | Keith | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Rodriguez,E | Demoted to reserve roster | | | Before |
| 4/8/2025 | TOR | Rodriguez,E | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Rodriguez,E | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Suter | Promoted to active roster | | | Before |
| 4/11/2025 | AUR | Acuna,J | Promoted to active roster | | | Before |
| 4/11/2025 | AUR | Iglesias,J | Placed on Injured List | | 4/9/2025 | Before |
| 4/14/2025 | CAP | Eovaldi | Placed on Injured List | | 4/14/2025 | Before |
| 4/14/2025 | CAP | Pfaadt | Promoted to active roster | | | Before |
| 4/14/2025 | HOL | Cave | Promoted to active roster | | | Before |
| 4/14/2025 | HOL | Urshela | Demoted to reserve roster | | | Before |
| 4/14/2025 | NHP | deGrom | Signed | | | Before |
| 4/17/2025 | CAP | Long | Promoted to active roster | | | Before |
| 4/17/2025 | CAP | Otanez | Placed on Injured List | | 4/15/2025 | Before |
| 4/17/2025 | RMH | Bichette | Placed on Injured List | | 4/15/2025 | Before |
| 4/17/2025 | RMH | Walls | Promoted to active roster | | | Before |
| 4/17/2025 | SPR | Deluca | Promoted to active roster | | | Before |
| 4/17/2025 | SPR | Harris II | Placed on Injured List | | 4/17/2025 | Before |
| 4/20/2025 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 4/20/2025 | DSP | Knack | Promoted to active roster | | | Before |
| 4/20/2025 | DSP | Rea | Promoted to active roster | | | Before |
| 4/20/2025 | DSP | Yamamoto | Demoted to reserve roster | | | Before |
| 4/20/2025 | NHP | Nelson,R | Placed on Injured List | | 4/18/2025 | Before |
| 4/20/2025 | OLL | Johnson,P | Demoted to reserve roster | | | Before |
| 4/20/2025 | OLL | Rodriguez,R | Promoted to active roster | | | Before |
| 4/20/2025 | PUE | Cleavinger | Promoted to active roster | | | Before |
| 4/20/2025 | PUE | Fry | Placed on Injured List | | 4/18/2025 | Before |
| 4/20/2025 | PUE | Martin,A | Promoted to active roster | | | Before |
| 4/20/2025 | PUE | Miller,T | Placed on Injured List | | 4/19/2025 | Before |
| 4/23/2025 | CAP | Lee,J | Promoted to active roster | | | Before |
| 4/23/2025 | CAP | Mullins | Placed on Injured List | | 4/23/2025 | Before |
| 4/23/2025 | CUY | Hurter | Demoted to reserve roster | | | Before |
| 4/23/2025 | CUY | Jacob | Promoted to active roster | | | Before |
| 4/23/2025 | CUY | Lukes | Demoted to reserve roster | | | Before |
| 4/23/2025 | CUY | Tromp | Promoted to active roster | | | Before |
| 4/23/2025 | CUY | Varland,L | Demoted to reserve roster | | | Before |
| 4/23/2025 | CUY | Westburg | Placed on Injured List | | 4/22/2025 | Before |
| 4/23/2025 | HOL | Banda | Demoted to reserve roster | | | Before |
| 4/23/2025 | HOL | Bellozo | Promoted to active roster | | | Before |
| 4/23/2025 | HOL | Flaherty | Placed on Injured List | | 4/23/2025 | Before |
| 4/23/2025 | HOL | Leiter,M | Promoted to active roster | | | Before |
| 4/23/2025 | NHP | Lopez,R | Placed on Injured List | | 4/21/2025 | Before |
| 4/23/2025 | NHP | Scherzer | Promoted to active roster | | | Before |
| 4/23/2025 | TOR | Amaya,M | Activated from Injured List | | | Before |
| 4/23/2025 | TOR | Bednar | Promoted to active roster | | | Before |
| 4/23/2025 | TOR | Betts | Activated from Injured List | | | Before |
| 4/23/2025 | TOR | Crow-Armstrong | Demoted to reserve roster | | | Before |
| 4/23/2025 | TOR | Goodman | Demoted to reserve roster | | | Before |
| 4/23/2025 | TOR | Greene,H | Activated from Injured List | | | Before |
| 4/23/2025 | TOR | Rodriguez,E | Demoted to reserve roster | | | Before |
| 4/23/2025 | TOR | Uceta | Demoted to reserve roster | | | Before |
| 4/26/2025 | AUR | Acuna,J | Demoted to reserve roster | | | Before |
| 4/26/2025 | AUR | Iglesias,J | Activated from Injured List | | | Before |
| 4/26/2025 | CAP | Herrera,I | Placed on Injured List | | 4/25/2025 | Before |
| 4/26/2025 | CAP | Long | Demoted to reserve roster | | | Before |
| 4/26/2025 | CAP | Murphy,S | Promoted to active roster | | | Before |
| 4/26/2025 | CAP | Otanez | Activated from Injured List | | | Before |
| 4/26/2025 | DSP | Darvish | Promoted to active roster | | | Before |
| 4/26/2025 | DSP | Knack | Demoted to reserve roster | | | Before |
| 4/26/2025 | DSP | Morgan | Demoted to reserve roster | | | Before |
| 4/26/2025 | DSP | Stanek | Promoted to active roster | | | Before |
| 4/26/2025 | DUR | Law | Placed on Injured List | | 4/24/2025 | Before |
| 4/26/2025 | DUR | Mears | Promoted to active roster | | | Before |
| 4/26/2025 | NDF | Lively | Signed | | | Before |
| 4/26/2025 | NDF | Stowers | Released | | | Before |
| 4/26/2025 | NDF | Stowers | Released | | | Before |
| 4/26/2025 | NDF | Stowers | Released | | | Before |
| 4/26/2025 | NDF | Stowers | Signed | | | Before |
| 4/26/2025 | NDF | Stowers | Signed | | | Before |
| 4/26/2025 | NDF | Stowers | Signed | | | Before |
| 4/26/2025 | NDF | Stowers | Signed | | | Before |
| 4/26/2025 | NDF | Stripling | Signed | | | Before |
| 4/29/2025 | AUR | McKinstry | Promoted to active roster | | | Before |
| 4/29/2025 | AUR | Vientos | Placed on Injured List | | 4/27/2025 | Before |
| 4/29/2025 | CUY | Acuna,R | Placed on Injured List | | 4/27/2025 | Before |
| 4/29/2025 | CUY | Lukes | Promoted to active roster | | | Before |
| 5/2/2025 | DSP | McCutchen | Placed on Injured List | | 5/2/2025 | Before |
| 5/2/2025 | DSP | Suwinski | Promoted to active roster | | | Before |
| 5/2/2025 | NHP | deGrom | Demoted to reserve roster | | | Before |
| 5/2/2025 | NHP | Lopez,R | Activated from Injured List | | | Before |
| 5/2/2025 | OLL | Ashcraft | Promoted to active roster | | | Before |
| 5/2/2025 | OLL | Fedde | Placed on Injured List | | 5/2/2025 | Before |
| 5/5/2025 | AUR | Conine | Demoted to reserve roster | | | Before |
| 5/5/2025 | AUR | Larnach | Activated from Injured List | | | Before |
| 5/5/2025 | CAP | Lee,J | Demoted to reserve roster | | | Before |
| 5/5/2025 | CAP | Mullins | Activated from Injured List | | | Before |
| 5/5/2025 | CGS | Buxton | Activated from Injured List | | | Before |
| 5/5/2025 | CGS | Trout | Demoted to reserve roster | | | Before |
| 5/5/2025 | CUY | Chaparro | Promoted to active roster | | | Before |
| 5/5/2025 | CUY | Marchan | Demoted to reserve roster | | | Before |
| 5/5/2025 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 5/5/2025 | DSP | Yamamoto | Promoted to active roster | | | Before |
| 5/5/2025 | DUR | Cabrera,E | Placed on Injured List | | 5/4/2025 | Before |
| 5/5/2025 | DUR | Springs | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Aldegheri | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Aldegheri | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Amaya,J | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Amaya,J | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Beeter | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Beeter | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Bellinger | Placed on Injured List | | 4/25/2025 | Before |
| 5/5/2025 | NDF | Brown,B | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Butto | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Chargois | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Feduccia | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Feduccia | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Foley | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | LeMahieu | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | LeMahieu | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Loperfido | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Lopez,Jaco | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Lopez,Jaco | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Malloy | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Matz | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Matz | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | McDonald | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | McDonald | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Millas | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Millas | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Musgrove | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Myers,D | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Pauley | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Pauley | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Pereda | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Pereda | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Phillips,E | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Rendon | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Rendon | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Shenton | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Shenton | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Stowers | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Stripling | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Thompson,K | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Wagner | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 5/5/2025 | PUE | Cleavinger | Demoted to reserve roster | | | Before |
| 5/5/2025 | PUE | Miller,T | Activated from Injured List | | | Before |
| 5/5/2025 | RMH | Bichette | Activated from Injured List | | | Before |
| 5/5/2025 | RMH | Walls | Demoted to reserve roster | | | Before |
| 5/5/2025 | TOR | Bednar | Demoted to reserve roster | | | Before |
| 5/5/2025 | TOR | Brown,H | Placed on Injured List | | 4/30/2025 | Before |
| 5/5/2025 | TOR | Rodriguez,E | Promoted to active roster | | | Before |
| 5/5/2025 | TOR | Uceta | Promoted to active roster | | | Before |
| 5/8/2025 | HOL | Bellozo | Demoted to reserve roster | | | Before |
| 5/8/2025 | HOL | Flaherty | Activated from Injured List | | | Before |
| 5/8/2025 | SPR | Candelario | Activated from Injured List | | | Before |
| 5/8/2025 | SPR | Deluca | Demoted to reserve roster | | | Before |
| 5/8/2025 | SPR | Flores | Demoted to reserve roster | | | Before |
| 5/8/2025 | SPR | Harris II | Activated from Injured List | | | Before |
| 5/11/2025 | AUR | Iglesias,J | Placed on Injured List | | 5/9/2025 | Before |
| 5/11/2025 | AUR | Vientos | Activated from Injured List | | | Before |
| 5/11/2025 | CAP | Caminero | Demoted to reserve roster | | | Before |
| 5/11/2025 | CAP | Lee,J | Promoted to active roster | | | Before |
| 5/11/2025 | CAP | Long | Promoted to active roster | | | Before |
| 5/11/2025 | CAP | Tucker,K | Placed on Injured List | | 5/11/2025 | Before |
| 5/11/2025 | DUR | Crews | Promoted to active roster | | | Before |
| 5/11/2025 | DUR | Hayes | Placed on Injured List | | 5/6/2025 | Before |
| 5/11/2025 | SPR | Imanaga | Placed on Injured List | | 5/11/2025 | Before |
| 5/11/2025 | SPR | Shuster | Signed | | | Before |
| 5/11/2025 | TOR | Crow-Armstrong | Promoted to active roster | | | Before |
| 5/11/2025 | TOR | Manoah | Promoted to active roster | | | Before |
| 5/11/2025 | TOR | McCarthy | Placed on Injured List | | 5/9/2025 | Before |
| 5/11/2025 | TOR | Rodriguez,E | Demoted to reserve roster | | | Before |
| 5/14/2025 | NHP | Nelson,R | Activated from Injured List | | | Before |
| 5/14/2025 | NHP | Scherzer | Demoted to reserve roster | | | Before |
| 5/14/2025 | OLL | Ashcraft | Demoted to reserve roster | | | Before |
| 5/14/2025 | OLL | Fedde | Activated from Injured List | | | Before |
| 5/14/2025 | PUE | Fry | Activated from Injured List | | | Before |
| 5/14/2025 | PUE | Young,J | Demoted to reserve roster | | | Before |
| 5/14/2025 | TOR | Bednar | Promoted to active roster | | | Before |
| 5/14/2025 | TOR | Manoah | Demoted to reserve roster | | | Before |
| 5/14/2025 | TOR | Manoah | Promoted to active roster | | | Before |
| 5/14/2025 | TOR | Manoah | Demoted to reserve roster | | | Before |
| 5/14/2025 | TOR | Young,D | Demoted to reserve roster | | | Before |
| 5/14/2025 | TOR | Young,D | Promoted to active roster | | | Before |
| 5/17/2025 | CAP | Eovaldi | Activated from Injured List | | | Before |
| 5/17/2025 | CAP | Pfaadt | Demoted to reserve roster | | | Before |
| 5/17/2025 | CUY | Acuna,R | Activated from Injured List | | | Before |
| 5/17/2025 | CUY | Hurter | Promoted to active roster | | | Before |
| 5/17/2025 | CUY | Jacob | Demoted to reserve roster | | | Before |
| 5/17/2025 | CUY | Marinaccio | Promoted to active roster | | | Before |
| 5/17/2025 | CUY | Norby | Demoted to reserve roster | | | Before |
| 5/17/2025 | CUY | Stratton,H | Demoted to reserve roster | | | Before |
| 5/17/2025 | DSP | McCutchen | Activated from Injured List | | | Before |
| 5/17/2025 | DSP | Suwinski | Demoted to reserve roster | | | Before |
| 5/17/2025 | NHP | Grisham | Promoted to active roster | | | Before |
| 5/17/2025 | NHP | Robles | Placed on Injured List | | 5/15/2025 | Before |
| 5/20/2025 | AUR | Iglesias,J | Activated from Injured List | | | Before |
| 5/20/2025 | AUR | McKinstry | Demoted to reserve roster | | | Before |
| 5/20/2025 | CED | McGuire | Placed on Injured List | | 5/18/2025 | Before |
| 5/20/2025 | CED | Torrens | Promoted to active roster | | | Before |
| 5/20/2025 | HOL | Kochanowicz | Promoted to active roster | | | Before |
| 5/20/2025 | HOL | Littell | Demoted to reserve roster | | | Before |
| 5/20/2025 | TOR | Brown,H | Activated from Injured List | | | Before |
| 5/20/2025 | TOR | Uceta | Demoted to reserve roster | | | Before |
| 5/23/2025 | AUR | Javier | Promoted to active roster | | | Before |
| 5/23/2025 | AUR | Kikuchi | Demoted to reserve roster | | | Before |
| 5/23/2025 | CAP | Herrera,I | Activated from Injured List | | | Before |
| 5/23/2025 | CAP | Lee,J | Demoted to reserve roster | | | Before |
| 5/23/2025 | CAP | Murphy,S | Demoted to reserve roster | | | Before |
| 5/23/2025 | CAP | Tucker,K | Activated from Injured List | | | Before |
| 5/23/2025 | DSP | Scott,Tan | Released | | | Before |
| 5/23/2025 | DSP | Scott,Tan | Signed | | | Before |
| 5/23/2025 | DSP | Scott,Tan | Signed | | | Before |
| 5/23/2025 | DSP | Stanek | Demoted to reserve roster | | | Before |
| 5/23/2025 | NDF | Bellinger | Activated from Injured List | | | Before |
| 5/23/2025 | NDF | Malloy | Demoted to reserve roster | | | Before |
| 5/23/2025 | SPR | McCann,J | Placed on Injured List | | 5/23/2025 | Before |
| 5/23/2025 | SPR | Vazquez,C | Signed | | | Before |
| 5/23/2025 | TOR | Crow-Armstrong | Demoted to reserve roster | | | Before |
| 5/23/2025 | TOR | McCarthy | Activated from Injured List | | | Before |
| 5/23/2025 | TOR | Uceta | Promoted to active roster | | | Before |
| 5/23/2025 | TOR | Young,D | Demoted to reserve roster | | | Before |
| 5/26/2025 | AUR | Gurriel,L | Placed on Injured List | | 5/26/2025 | Before |
| 5/26/2025 | AUR | Noel | Promoted to active roster | | | Before |
| 5/26/2025 | CUY | Buehler | Placed on Injured List | | 5/25/2025 | Before |
| 5/26/2025 | CUY | Ginn | Promoted to active roster | | | Before |
| 5/26/2025 | HOL | Kochanowicz | Placed on Injured List | | 5/25/2025 | Before |
| 5/26/2025 | HOL | Littell | Promoted to active roster | | | Before |
| 5/26/2025 | OLL | Johnson,P | Promoted to active roster | | | Before |
| 5/26/2025 | OLL | Rodriguez,R | Demoted to reserve roster | | | Before |
| 5/26/2025 | SPR | Imanaga | Activated from Injured List | | | Before |
| 5/26/2025 | SPR | Thornton | Demoted to reserve roster | | | Before |
| 5/29/2025 | DUR | Law | Activated from Injured List | | | Before |
| 5/29/2025 | DUR | Mears | Demoted to reserve roster | | | Before |
| 5/29/2025 | DUR | Mitchell | Promoted to active roster | | | Before |
| 5/29/2025 | DUR | Story | Demoted to reserve roster | | | Before |
| 5/29/2025 | NDF | Brown,B | Demoted to reserve roster | | | Before |
| 5/29/2025 | NDF | Chargois | Promoted to active roster | | | Before |
| 5/29/2025 | NDF | Foley | Promoted to active roster | | | Before |
| 5/29/2025 | NDF | Musgrove | Promoted to active roster | | | Before |
| 5/29/2025 | NDF | Myers,D | Demoted to reserve roster | | | Before |
| 5/29/2025 | NDF | Phillips,E | Promoted to active roster | | | Before |
| 5/29/2025 | NDF | Puk | Placed on Injured List | | 5/25/2025 | Before |
| 5/29/2025 | NDF | Williams,T | Placed on Injured List | | 5/17/2025 | Before |
| 5/29/2025 | NHP | Grisham | Demoted to reserve roster | | | Before |
| 5/29/2025 | NHP | Robles | Activated from Injured List | | | Before |
| 5/31/2025 | CUY | Bibee | Traded away | NDF | | After |
| 5/31/2025 | CUY | Chapman,A | Traded away | NDF | | After |
| 5/31/2025 | CUY | Lively | Acquired via trade | NDF | | After |
| 5/31/2025 | CUY | Myers,D | Acquired via trade | NDF | | After |
| 5/31/2025 | CUY | Rendon | Acquired via trade | NDF | | After |
| 5/31/2025 | CUY | Stowers | Acquired via trade | NDF | | After |
| 5/31/2025 | CUY | Stripling | Acquired via trade | NDF | | After |
| 5/31/2025 | NDF | Bibee | Acquired via trade | CUY | | After |
| 5/31/2025 | NDF | Chapman,A | Acquired via trade | CUY | | After |
| 5/31/2025 | NDF | Lively | Traded away | CUY | | After |
| 5/31/2025 | NDF | Myers,D | Traded away | CUY | | After |
| 5/31/2025 | NDF | Rendon | Traded away | CUY | | After |
| 5/31/2025 | NDF | Stowers | Traded away | CUY | | After |
| 5/31/2025 | NDF | Stripling | Traded away | CUY | | After |
| 6/1/2025 | AUR | Adam | Placed on Injured List | | 5/31/2025 | Before |
| 6/1/2025 | AUR | Roupp | Promoted to active roster | | | Before |
| 6/1/2025 | CUY | Stratton,H | Promoted to active roster | | | Before |
| 6/1/2025 | NDF | Brown,B | Promoted to active roster | | | Before |
| 6/1/2025 | NDF | Chargois | Demoted to reserve roster | | | Before |
| 6/1/2025 | NDF | Musgrove | Demoted to reserve roster | | | Before |
| 6/1/2025 | NDF | Phillips,E | Demoted to reserve roster | | | Before |
| 6/1/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 6/1/2025 | OLL | Ashcraft | Promoted to active roster | | | Before |
| 6/1/2025 | OLL | Skubal | Placed on Injured List | | 5/31/2025 | Before |
| 6/1/2025 | PUE | Ferrer | Demoted to reserve roster | | | Before |
| 6/1/2025 | PUE | Guenther | Promoted to active roster | | | Before |
| 6/1/2025 | PUE | Lovelady | Demoted to reserve roster | | | Before |
| 6/1/2025 | PUE | Morejon | Promoted to active roster | | | Before |
| 6/4/2025 | CGS | Peguero,E | Promoted to active roster | | | Before |
| 6/4/2025 | CGS | Ryan,Ri | Demoted to reserve roster | | | Before |
| 6/4/2025 | CGS | Trout | Promoted to active roster | | | Before |
| 6/4/2025 | CGS | Yoshida | Placed on Injured List | | 5/30/2025 | Before |
| 6/4/2025 | PUE | Bieber | Promoted to active roster | | | Before |
| 6/4/2025 | PUE | Schmidt | Placed on Injured List | | 6/3/2025 | Before |
| 6/7/2025 | AUR | Javier | Demoted to reserve roster | | | Before |
| 6/7/2025 | AUR | Kikuchi | Promoted to active roster | | | Before |
| 6/7/2025 | CUY | Garrett,B | Promoted to active roster | | | Before |
| 6/7/2025 | CUY | Garrett,S | Demoted to reserve roster | | | Before |
| 6/7/2025 | CUY | Garrett,S | Promoted to active roster | | | Before |
| 6/7/2025 | CUY | Lukes | Demoted to reserve roster | | | Before |
| 6/7/2025 | CUY | Marchan | Promoted to active roster | | | Before |
| 6/7/2025 | CUY | Stratton,H | Placed on Injured List | | 6/3/2025 | Before |
| 6/7/2025 | CUY | Tromp | Demoted to reserve roster | | | Before |
| 6/7/2025 | CUY | Westburg | Activated from Injured List | | | Before |
| 6/7/2025 | HOL | Kochanowicz | Activated from Injured List | | | Before |
| 6/7/2025 | HOL | Littell | Demoted to reserve roster | | | Before |
| 6/7/2025 | NDF | Foley | Demoted to reserve roster | | | Before |
| 6/7/2025 | NDF | Puk | Activated from Injured List | | | Before |
| 6/7/2025 | NDF | Thompson,K | Demoted to reserve roster | | | Before |
| 6/7/2025 | NDF | Thompson,K | Promoted to active roster | | | Before |
| 6/7/2025 | NDF | Wagner | Demoted to reserve roster | | | Before |
| 6/7/2025 | NDF | Williams,T | Activated from Injured List | | | Before |
| 6/7/2025 | PUE | Marsh,B | Placed on Injured List | | 6/6/2025 | Before |
| 6/7/2025 | PUE | Young,J | Promoted to active roster | | | Before |
| 6/10/2025 | OLL | Gorman | Promoted to active roster | | | Before |
| 6/10/2025 | OLL | Rojas,M | Placed on Injured List | | 6/9/2025 | Before |
| 6/10/2025 | RMH | Friedl | Promoted to active roster | | | Before |
| 6/10/2025 | RMH | Perkins | Placed on Injured List | | 6/8/2025 | Before |
| 6/13/2025 | CAP | Caminero | Promoted to active roster | | | Before |
| 6/13/2025 | CAP | Rodriguez,M | Demoted to reserve roster | | | Before |
| 6/13/2025 | DSP | Darvish | Promoted to active roster | | | Before |
| 6/13/2025 | DSP | Yamamoto | Demoted to reserve roster | | | Before |
| 6/16/2025 | CLE | Bivens | Demoted to reserve roster | | | Before |
| 6/16/2025 | CLE | Meyer | Promoted to active roster | | | Before |
| 6/16/2025 | SPR | McCann,J | Activated from Injured List | | | Before |
| 6/16/2025 | SPR | Vazquez,C | Demoted to reserve roster | | | Before |
| 6/18/2025 | CGS | Canha | Acquired via trade | HAV | | After |
| 6/18/2025 | CGS | Harrison | Traded away | HAV | | After |
| 6/18/2025 | CGS | Hiura | Acquired via trade | HAV | | After |
| 6/18/2025 | CGS | Kelly,Z | Acquired via trade | HAV | | After |
| 6/18/2025 | CGS | Moore,M | Acquired via trade | HAV | | After |
| 6/18/2025 | CGS | Pearson | Acquired via trade | HAV | | After |
| 6/18/2025 | CGS | Realmuto | Acquired via trade | HAV | | After |
| 6/18/2025 | CGS | Trout | Traded away | HAV | | After |
| 6/18/2025 | CGS | Valdez,E | Acquired via trade | HAV | | After |
| 6/18/2025 | HAV | Canha | Traded away | CGS | | After |
| 6/18/2025 | HAV | Harrison | Acquired via trade | CGS | | After |
| 6/18/2025 | HAV | Hiura | Traded away | CGS | | After |
| 6/18/2025 | HAV | Kelly,Z | Traded away | CGS | | After |
| 6/18/2025 | HAV | Moore,M | Traded away | CGS | | After |
| 6/18/2025 | HAV | Pearson | Traded away | CGS | | After |
| 6/18/2025 | HAV | Realmuto | Traded away | CGS | | After |
| 6/18/2025 | HAV | Trout | Acquired via trade | CGS | | After |
| 6/18/2025 | HAV | Valdez,E | Traded away | CGS | | After |
| 6/19/2025 | CGS | Anderson,Ti | Signed | | | Before |
| 6/19/2025 | CGS | Anderson,Ti | Demoted to reserve roster | | | Before |
| 6/19/2025 | CGS | Canha | Demoted to reserve roster | | | Before |
| 6/19/2025 | CGS | Kelly,Z | Demoted to reserve roster | | | Before |
| 6/19/2025 | CGS | Soderstrom | Demoted to reserve roster | | | Before |
| 6/19/2025 | CGS | Yoshida | Activated from Injured List | | | Before |
| 6/19/2025 | DSP | Morgan | Promoted to active roster | | | Before |
| 6/19/2025 | DSP | Rea | Demoted to reserve roster | | | Before |
| 6/19/2025 | HOL | Banda | Promoted to active roster | | | Before |
| 6/19/2025 | HOL | Leiter,M | Demoted to reserve roster | | | Before |
| 6/19/2025 | OLL | Ashcraft | Demoted to reserve roster | | | Before |
| 6/19/2025 | OLL | Skubal | Activated from Injured List | | | Before |
| 6/19/2025 | PUE | Bieber | Demoted to reserve roster | | | Before |
| 6/19/2025 | PUE | Diaz,Yi | Promoted to active roster | | | Before |
| 6/19/2025 | PUE | Marsh,B | Activated from Injured List | | | Before |
| 6/19/2025 | PUE | Young,J | Demoted to reserve roster | | | Before |
| 6/21/2025 | HAV | Bell | Acquired via trade | OLL | | After |
| 6/21/2025 | HAV | Clemens | Acquired via trade | OLL | | After |
| 6/21/2025 | HAV | Marsh,A | Traded away | OLL | | After |
| 6/21/2025 | HAV | Pham | Traded away | OLL | | After |
| 6/21/2025 | HAV | Stubbs | Acquired via trade | OLL | | After |
| 6/21/2025 | OLL | Bell | Traded away | HAV | | After |
| 6/21/2025 | OLL | Clemens | Traded away | HAV | | After |
| 6/21/2025 | OLL | Marsh,A | Acquired via trade | HAV | | After |
| 6/21/2025 | OLL | Pham | Acquired via trade | HAV | | After |
| 6/21/2025 | OLL | Stubbs | Traded away | HAV | | After |
| 6/22/2025 | CED | Birdsong | Demoted to reserve roster | | | Before |
| 6/22/2025 | CED | Hernandez,C | Demoted to reserve roster | | | Before |
| 6/22/2025 | CED | Hernandez,D | Promoted to active roster | | | Before |
| 6/22/2025 | CED | Lynch | Promoted to active roster | | | Before |
| 6/22/2025 | CGS | Canha | Promoted to active roster | | | Before |
| 6/22/2025 | CGS | Hicks,J | Demoted to reserve roster | | | Before |
| 6/22/2025 | CGS | Naylor,B | Demoted to reserve roster | | | Before |
| 6/22/2025 | CGS | Soderstrom | Promoted to active roster | | | Before |
| 6/22/2025 | CUY | Buehler | Activated from Injured List | | | Before |
| 6/22/2025 | CUY | Funderburk | Promoted to active roster | | | Before |
| 6/22/2025 | CUY | Garrett,B | Demoted to reserve roster | | | Before |
| 6/22/2025 | CUY | Hurter | Demoted to reserve roster | | | Before |
| 6/22/2025 | CUY | Myers,D | Promoted to active roster | | | Before |
| 6/22/2025 | CUY | Wilson,W | Demoted to reserve roster | | | Before |
| 6/22/2025 | DUR | Aranda | Promoted to active roster | | | Before |
| 6/22/2025 | DUR | Cabrera,E | Activated from Injured List | | | Before |
| 6/22/2025 | DUR | Crews | Demoted to reserve roster | | | Before |
| 6/22/2025 | DUR | Hayes | Activated from Injured List | | | Before |
| 6/22/2025 | DUR | Smith,P | Demoted to reserve roster | | | Before |
| 6/22/2025 | DUR | Springs | Demoted to reserve roster | | | Before |
| 6/22/2025 | HAV | Guerrero,L | Demoted to reserve roster | | | Before |
| 6/22/2025 | HAV | Harrison | Promoted to active roster | | | Before |
| 6/22/2025 | HAV | Stubbs | Promoted to active roster | | | Before |
| 6/22/2025 | HOL | Bellozo | Promoted to active roster | | | Before |
| 6/22/2025 | HOL | Hernandez,En | Promoted to active roster | | | Before |
| 6/22/2025 | HOL | Pivetta | Placed on Injured List | | 6/18/2025 | Before |
| 6/22/2025 | HOL | Suzuki | Placed on Injured List | | 6/19/2025 | Before |
| 6/22/2025 | OLL | Marsh,A | Demoted to reserve roster | | | Before |
| 6/22/2025 | OLL | Rojas,M | Activated from Injured List | | | Before |
| 6/24/2025 | HOL | Caratini | Traded away | OLL | | After |
| 6/24/2025 | HOL | Dubin | Acquired via trade | OLL | | After |
| 6/24/2025 | HOL | Ibanez | Traded away | OLL | | After |
| 6/24/2025 | HOL | Pages,P | Acquired via trade | OLL | | After |
| 6/24/2025 | HOL | Rodriguez,R | Acquired via trade | OLL | | After |
| 6/24/2025 | HOL | Rogers,Ta | Traded away | OLL | | After |
| 6/24/2025 | HOL | Ward | Acquired via trade | OLL | | After |
| 6/24/2025 | OLL | Caratini | Acquired via trade | HOL | | After |
| 6/24/2025 | OLL | Dubin | Traded away | HOL | | After |
| 6/24/2025 | OLL | Ibanez | Acquired via trade | HOL | | After |
| 6/24/2025 | OLL | Pages,P | Traded away | HOL | | After |
| 6/24/2025 | OLL | Rodriguez,R | Traded away | HOL | | After |
| 6/24/2025 | OLL | Rogers,Ta | Acquired via trade | HOL | | After |
| 6/24/2025 | OLL | Ward | Traded away | HOL | | After |
| 6/25/2025 | AUR | Adam | Activated from Injured List | | | Before |
| 6/25/2025 | AUR | Eflin | Placed on Injured List | | 6/20/2025 | Before |
| 6/25/2025 | AUR | Gurriel,L | Activated from Injured List | | | Before |
| 6/25/2025 | AUR | Javier | Promoted to active roster | | | Before |
| 6/25/2025 | AUR | Noel | Demoted to reserve roster | | | Before |
| 6/25/2025 | AUR | Roupp | Placed on Injured List | | 6/17/2025 | Before |
| 6/25/2025 | CED | Corbin | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Freeland | Placed on Injured List | | 6/24/2025 | Before |
| 6/25/2025 | CED | Halvorsen | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Joe | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Mlodzinski | Demoted to reserve roster | | | Before |
| 6/25/2025 | CED | Romero | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Toglia | Demoted to reserve roster | | | Before |
| 6/25/2025 | CED | Treinen | Demoted to reserve roster | | | Before |
| 6/25/2025 | CGS | Buxton | Placed on Injured List | | 6/24/2025 | Before |
| 6/25/2025 | CGS | Kelly,Z | Promoted to active roster | | | Before |
| 6/25/2025 | HOL | Hill,T | Promoted to active roster | | | Before |
| 6/25/2025 | HOL | Kochanowicz | Placed on Injured List | | 6/14/2025 | Before |
| 6/25/2025 | HOL | Littell | Promoted to active roster | | | Before |
| 6/25/2025 | NHP | Grisham | Promoted to active roster | | | Before |
| 6/25/2025 | NHP | Robles | Placed on Injured List | | 6/24/2025 | Before |
| 6/25/2025 | OLL | Bender | Demoted to reserve roster | | | Before |
| 6/25/2025 | OLL | Marsh,A | Promoted to active roster | | | Before |
| 6/25/2025 | OLL | Staumont | Demoted to reserve roster | | | Before |
| 6/25/2025 | RMH | Brasier | Demoted to reserve roster | | | Before |
| 6/25/2025 | RMH | Calhoun | Placed on Injured List | | 6/25/2025 | Before |
| 6/25/2025 | RMH | Encarnacion | Promoted to active roster | | | Before |
| 6/25/2025 | RMH | Harris,H | Promoted to active roster | | | Before |
| 6/25/2025 | TOR | Uceta | Demoted to reserve roster | | | Before |
| 6/25/2025 | TOR | Young,D | Promoted to active roster | | | Before |
| 6/28/2025 | OLL | Rojas,M | Placed on Injured List | | 6/28/2025 | Before |
| 6/28/2025 | OLL | Taylor,C | Promoted to active roster | | | Before |
| 7/1/2025 | CED | Baker,L | Promoted to active roster | | | Before |
| 7/1/2025 | CED | Carpenter,K | Demoted to reserve roster | | | Before |
| 7/1/2025 | CED | Fitts | Promoted to active roster | | | Before |
| 7/1/2025 | CED | Hays | Demoted to reserve roster | | | Before |
| 7/1/2025 | CED | Lynch | Placed on Injured List | | 6/28/2025 | Before |
| 7/1/2025 | CED | McGuire | Activated from Injured List | | | Before |
| 7/1/2025 | CED | McGuire | Demoted to reserve roster | | | Before |
| 7/1/2025 | CED | Toglia | Promoted to active roster | | | Before |
| 7/3/2025 | AUR | Adam | Traded away | CLE | | After |
| 7/3/2025 | AUR | Castillo,L | Acquired via trade | CAP | | After |
| 7/3/2025 | AUR | Eflin | Traded away | CAP | | After |
| 7/3/2025 | AUR | Erceg | Traded away | CLE | | After |
| 7/3/2025 | AUR | Fortes | Traded away | CAP | | After |
| 7/3/2025 | AUR | Iglesias,J | Traded away | CLE | | After |
| 7/3/2025 | AUR | Jimenez,J | Traded away | CLE | | After |
| 7/3/2025 | AUR | Kikuchi | Traded away | CLE | | After |
| 7/3/2025 | AUR | Lee,B | Acquired via trade | CLE | | After |
| 7/3/2025 | AUR | Meyer | Acquired via trade | CLE | | After |
| 7/3/2025 | AUR | Noel | Traded away | CAP | | After |
| 7/3/2025 | AUR | Rosario,A | Acquired via trade | CLE | | After |
| 7/3/2025 | AUR | Ross | Acquired via trade | CLE | | After |
| 7/3/2025 | AUR | Sanoja | Acquired via trade | CLE | | After |
| 7/3/2025 | AUR | Vientos | Traded away | CLE | | After |
| 7/3/2025 | CAP | Castillo,L | Traded away | AUR | | After |
| 7/3/2025 | CAP | Eflin | Acquired via trade | AUR | | After |
| 7/3/2025 | CAP | Fortes | Acquired via trade | AUR | | After |
| 7/3/2025 | CAP | Noel | Acquired via trade | AUR | | After |
| 7/3/2025 | CED | Minter | Acquired via trade | HOL | | After |
| 7/3/2025 | CLE | Adam | Acquired via trade | AUR | | After |
| 7/3/2025 | CLE | Erceg | Acquired via trade | AUR | | After |
| 7/3/2025 | CLE | Iglesias,J | Acquired via trade | AUR | | After |
| 7/3/2025 | CLE | Jimenez,J | Acquired via trade | AUR | | After |
| 7/3/2025 | CLE | Kikuchi | Acquired via trade | AUR | | After |
| 7/3/2025 | CLE | Lee,B | Traded away | AUR | | After |
| 7/3/2025 | CLE | Meyer | Traded away | AUR | | After |
| 7/3/2025 | CLE | Rosario,A | Traded away | AUR | | After |
| 7/3/2025 | CLE | Ross | Traded away | AUR | | After |
| 7/3/2025 | CLE | Sanoja | Traded away | AUR | | After |
| 7/3/2025 | CLE | Vientos | Acquired via trade | AUR | | After |
| 7/3/2025 | DSP | Hilliard | Traded away | TOR | | After |
| 7/3/2025 | DSP | McCarthy | Acquired via trade | TOR | | After |
| 7/3/2025 | DSP | Walker,R | Traded away | TOR | | After |
| 7/3/2025 | DSP | Woodford | Acquired via trade | TOR | | After |
| 7/3/2025 | DSP | Young,D | Acquired via trade | TOR | | After |
| 7/3/2025 | HOL | Minter | Traded away | CED | | After |
| 7/3/2025 | TOR | Hilliard | Acquired via trade | DSP | | After |
| 7/3/2025 | TOR | McCarthy | Traded away | DSP | | After |
| 7/3/2025 | TOR | Walker,R | Acquired via trade | DSP | | After |
| 7/3/2025 | TOR | Woodford | Traded away | DSP | | After |
| 7/3/2025 | TOR | Young,D | Traded away | DSP | | After |
| 7/4/2025 | AUR | Conine | Promoted to active roster | | | Before |
| 7/4/2025 | AUR | Meyer | Demoted to reserve roster | | | Before |
| 7/4/2025 | AUR | Zeferjahn | Promoted to active roster | | | Before |
| 7/4/2025 | CAP | Caminero | Demoted to reserve roster | | | Before |
| 7/4/2025 | CAP | Noel | Promoted to active roster | | | Before |
| 7/4/2025 | CAP | Pfaadt | Promoted to active roster | | | Before |
| 7/4/2025 | CLE | Alexander,S | Demoted to reserve roster | | | Before |
| 7/4/2025 | CLE | Kjerstad | Demoted to reserve roster | | | Before |
| 7/4/2025 | CLE | Lopez,Jo | Demoted to reserve roster | | | Before |
| 7/4/2025 | CLE | Rocchio | Demoted to reserve roster | | | Before |
| 7/4/2025 | CLE | Senga | Promoted to active roster | | | Before |
| 7/4/2025 | TOR | Crow-Armstrong | Promoted to active roster | | | Before |
| 7/4/2025 | TOR | Keith | Demoted to reserve roster | | | Before |
| 7/6/2025 | CLE | Alexander,T | Traded away | CUY | | After |
| 7/6/2025 | CLE | Encarnacn-Stran | Traded away | CUY | | After |
| 7/6/2025 | CLE | Fletcher,Do | Acquired via trade | CUY | | After |
| 7/6/2025 | CLE | Lively | Acquired via trade | CUY | | After |
| 7/6/2025 | CUY | Alexander,T | Acquired via trade | CLE | | After |
| 7/6/2025 | CUY | Andujar | Acquired via trade | DUR | | After |
| 7/6/2025 | CUY | Casas | Traded away | DUR | | After |
| 7/6/2025 | CUY | Crawford,K | Traded away | DUR | | After |
| 7/6/2025 | CUY | Encarnacn-Stran | Acquired via trade | CLE | | After |
| 7/6/2025 | CUY | Fletcher,Do | Traded away | CLE | | After |
| 7/6/2025 | CUY | Lively | Traded away | CLE | | After |
| 7/6/2025 | CUY | Mateo | Traded away | DUR | | After |
| 7/6/2025 | CUY | Mears | Acquired via trade | DUR | | After |
| 7/6/2025 | CUY | Mikolas | Acquired via trade | DUR | | After |
| 7/6/2025 | CUY | Springs | Acquired via trade | DUR | | After |
| 7/6/2025 | CUY | Wesneski | Acquired via trade | DUR | | After |
| 7/6/2025 | CUY | Woods Richardso | Traded away | DUR | | After |
| 7/6/2025 | DUR | Andujar | Traded away | CUY | | After |
| 7/6/2025 | DUR | Casas | Acquired via trade | CUY | | After |
| 7/6/2025 | DUR | Crawford,K | Acquired via trade | CUY | | After |
| 7/6/2025 | DUR | Mateo | Acquired via trade | CUY | | After |
| 7/6/2025 | DUR | Mears | Traded away | CUY | | After |
| 7/6/2025 | DUR | Mikolas | Traded away | CUY | | After |
| 7/6/2025 | DUR | Springs | Traded away | CUY | | After |
| 7/6/2025 | DUR | Wesneski | Traded away | CUY | | After |
| 7/6/2025 | DUR | Woods Richardso | Acquired via trade | CUY | | After |
| 7/7/2025 | AUR | Bigge | Promoted to active roster | | | Before |
| 7/7/2025 | AUR | Roupp | Activated from Injured List | | | Before |
| 7/7/2025 | AUR | Zeferjahn | Demoted to reserve roster | | | Before |
| 7/7/2025 | CAP | King,M | Placed on Injured List | | 7/5/2025 | Before |
| 7/7/2025 | CAP | Williams,G | Promoted to active roster | | | Before |
| 7/7/2025 | CLE | Alexander,S | Promoted to active roster | | | Before |
| 7/7/2025 | CLE | Senga | Demoted to reserve roster | | | Before |
| 7/7/2025 | CUY | Chaparro | Demoted to reserve roster | | | Before |
| 7/7/2025 | CUY | Funderburk | Demoted to reserve roster | | | Before |
| 7/7/2025 | CUY | Garrett,B | Promoted to active roster | | | Before |
| 7/7/2025 | CUY | Ginn | Demoted to reserve roster | | | Before |
| 7/7/2025 | CUY | Kelly,Me | Placed on Injured List | | 7/4/2025 | Before |
| 7/7/2025 | CUY | Marinaccio | Demoted to reserve roster | | | Before |
| 7/7/2025 | CUY | Mears | Promoted to active roster | | | Before |
| 7/7/2025 | CUY | Norby | Promoted to active roster | | | Before |
| 7/7/2025 | CUY | Palencia | Promoted to active roster | | | Before |
| 7/7/2025 | CUY | Stratton,H | Activated from Injured List | | | Before |
| 7/7/2025 | CUY | Stripling | Promoted to active roster | | | Before |
| 7/7/2025 | CUY | Wesneski | Promoted to active roster | | | Before |
| 7/7/2025 | DUR | Bradford | Demoted to reserve roster | | | Before |
| 7/7/2025 | DUR | Casas | Demoted to reserve roster | | | Before |
| 7/7/2025 | HOL | Bellozo | Demoted to reserve roster | | | Before |
| 7/7/2025 | HOL | Brito | Promoted to active roster | | | Before |
| 7/7/2025 | HOL | Kochanowicz | Activated from Injured List | | | Before |
| 7/7/2025 | NHP | Grisham | Demoted to reserve roster | | | Before |
| 7/7/2025 | NHP | Robles | Activated from Injured List | | | Before |
| 7/7/2025 | RMH | Blackmon | Demoted to reserve roster | | | Before |
| 7/7/2025 | RMH | Brasier | Promoted to active roster | | | Before |
| 7/7/2025 | RMH | Harris,H | Placed on Injured List | | 7/2/2025 | Before |
| 7/7/2025 | RMH | Perkins | Activated from Injured List | | | Before |
| 7/7/2025 | SPR | Candelario | Placed on Injured List | | 7/6/2025 | Before |
| 7/7/2025 | SPR | Flores | Promoted to active roster | | | Before |
| 7/7/2025 | WTB | Luzardo | Promoted to active roster | | | Before |
| 7/7/2025 | WTB | Williams,D | Demoted to reserve roster | | | Before |
| 7/10/2025 | CAP | Ashby | Demoted to reserve roster | | | Before |
| 7/10/2025 | CAP | Eflin | Activated from Injured List | | | Before |
| 7/10/2025 | CAP | Rodriguez,M | Promoted to active roster | | | Before |
| 7/10/2025 | CAP | Williams,G | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Baker,L | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Carpenter,K | Promoted to active roster | | | Before |
| 7/10/2025 | CED | Corbin | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Fitts | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Freeland | Activated from Injured List | | | Before |
| 7/10/2025 | CED | Halvorsen | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Hays | Promoted to active roster | | | Before |
| 7/10/2025 | CED | Joe | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Lynch | Activated from Injured List | | | Before |
| 7/10/2025 | HOL | Kochanowicz | Demoted to reserve roster | | | Before |
| 7/10/2025 | HOL | Pivetta | Activated from Injured List | | | Before |
| 7/10/2025 | HOL | Schneemann | Demoted to reserve roster | | | Before |
| 7/10/2025 | HOL | Suzuki | Activated from Injured List | | | Before |
| 7/10/2025 | OLL | Rojas,M | Activated from Injured List | | | Before |
| 7/10/2025 | OLL | Taylor,C | Demoted to reserve roster | | | Before |
| 7/12/2025 | AUR | Bader | Acquired via trade | CGS | | After |
| 7/12/2025 | AUR | Cantillo | Acquired via trade | CGS | | After |
| 7/12/2025 | AUR | Duvall | Acquired via trade | CGS | | After |
| 7/12/2025 | AUR | Kelly,Z | Acquired via trade | CGS | | After |
| 7/12/2025 | AUR | Miller,S | Acquired via trade | CGS | | After |
| 7/12/2025 | AUR | Pearson | Acquired via trade | CGS | | After |
| 7/12/2025 | AUR | Santander | Traded away | CGS | | After |
| 7/12/2025 | CGS | Bader | Traded away | AUR | | After |
| 7/12/2025 | CGS | Cantillo | Traded away | AUR | | After |
| 7/12/2025 | CGS | Duvall | Traded away | AUR | | After |
| 7/12/2025 | CGS | Kelly,Z | Traded away | AUR | | After |
| 7/12/2025 | CGS | Miller,S | Traded away | AUR | | After |
| 7/12/2025 | CGS | Pearson | Traded away | AUR | | After |
| 7/12/2025 | CGS | Santander | Acquired via trade | AUR | | After |
| 7/13/2025 | AUR | Acuna,J | Promoted to active roster | | | Before |
| 7/13/2025 | AUR | Bigge | Demoted to reserve roster | | | Before |
| 7/13/2025 | AUR | Kelly,Z | Demoted to reserve roster | | | Before |
| 7/13/2025 | AUR | McKinstry | Promoted to active roster | | | Before |
| 7/13/2025 | AUR | Miller,S | Demoted to reserve roster | | | Before |
| 7/13/2025 | AUR | Ortiz,LL | Demoted to reserve roster | | | Before |
| 7/13/2025 | AUR | Rosario,A | Placed on Injured List | | 7/11/2025 | Before |
| 7/13/2025 | CGS | Baz | Demoted to reserve roster | | | Before |
| 7/13/2025 | CGS | Garcia,M | Promoted to active roster | | | Before |
| 7/13/2025 | CGS | Hicks,J | Promoted to active roster | | | Before |
| 7/13/2025 | CGS | McCray | Promoted to active roster | | | Before |
| 7/13/2025 | CGS | Moore,M | Promoted to active roster | | | Before |
| 7/13/2025 | NHP | Hamilton,I | Demoted to reserve roster | | | Before |
| 7/13/2025 | NHP | Hodge | Promoted to active roster | | | Before |
| 7/13/2025 | NHP | Nardi | Demoted to reserve roster | | | Before |
| 7/13/2025 | NHP | Nunez,D | Promoted to active roster | | | Before |
| 7/15/2025 | DUR | Matz | Acquired via trade | NDF | | After |
| 7/15/2025 | DUR | Sanchez,G | Traded away | NDF | | After |
| 7/15/2025 | NDF | Matz | Traded away | DUR | | After |
| 7/15/2025 | NDF | Sanchez,G | Acquired via trade | DUR | | After |
| 7/16/2025 | AUR | Acuna,J | Demoted to reserve roster | | | Before |
| 7/16/2025 | AUR | Blanco,D | Demoted to reserve roster | | | Before |
| 7/16/2025 | AUR | Ortiz,LL | Promoted to active roster | | | Before |
| 7/16/2025 | AUR | Zeferjahn | Promoted to active roster | | | Before |
| 7/16/2025 | CAP | King,M | Activated from Injured List | | | Before |
| 7/16/2025 | CAP | Pfaadt | Demoted to reserve roster | | | Before |
| 7/16/2025 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 7/16/2025 | DSP | Knack | Promoted to active roster | | | Before |
| 7/16/2025 | DSP | Yamamoto | Promoted to active roster | | | Before |
| 7/16/2025 | DSP | Young,D | Demoted to reserve roster | | | Before |
| 7/16/2025 | DUR | Haase | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Brown,B | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Butto | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Chargois | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Chargois | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Chargois | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Contreras,WE | Placed on Injured List | | 7/13/2025 | Before |
| 7/16/2025 | NDF | Crouse | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Foley | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Lopez,Jaco | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Malloy | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Millas | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Pereda | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Pereda | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Phillips,E | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Stallings | Placed on Injured List | | 7/7/2025 | Before |
| 7/16/2025 | NDF | Thompson,K | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Wagner | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Williams,T | Demoted to reserve roster | | | Before |
| 7/18/2025 | CAP | Freeman,F | Acquired via trade | HOL | | After |
| 7/18/2025 | CAP | Hoffman | Traded away | HOL | | After |
| 7/18/2025 | CAP | Kelly,K | Acquired via trade | HOL | | After |
| 7/18/2025 | CAP | Murphy,S | Traded away | HOL | | After |
| 7/18/2025 | CAP | Pages,P | Acquired via trade | HOL | | After |
| 7/18/2025 | CAP | Pasquantino | Traded away | HOL | | After |
| 7/18/2025 | CGS | Flaherty | Acquired via trade | HOL | | After |
| 7/18/2025 | CGS | Hicks,J | Traded away | HOL | | After |
| 7/18/2025 | CGS | Ryan,Ri | Traded away | HOL | | After |
| 7/18/2025 | CLE | Baez | Traded away | HOL | | After |
| 7/18/2025 | CLE | Dunn,O | Traded away | HOL | | After |
| 7/18/2025 | CLE | Foley | Acquired via trade | HOL | | After |
| 7/18/2025 | CLE | Hicks,J | Acquired via trade | HOL | | After |
| 7/18/2025 | CLE | Hill,D | Acquired via trade | HOL | | After |
| 7/18/2025 | CLE | Matos | Traded away | HOL | | After |
| 7/18/2025 | DUR | Urshela | Acquired via trade | HOL | | After |
| 7/18/2025 | HOL | Baez | Acquired via trade | CLE | | After |
| 7/18/2025 | HOL | Dunn,O | Acquired via trade | CLE | | After |
| 7/18/2025 | HOL | Flaherty | Traded away | CGS | | After |
| 7/18/2025 | HOL | Foley | Traded away | CLE | | After |
| 7/18/2025 | HOL | Foley | Acquired via trade | NDF | | After |
| 7/18/2025 | HOL | Freeman,F | Traded away | CAP | | After |
| 7/18/2025 | HOL | Hicks,J | Traded away | CLE | | After |
| 7/18/2025 | HOL | Hicks,J | Acquired via trade | CGS | | After |
| 7/18/2025 | HOL | Hill,D | Traded away | CLE | | After |
| 7/18/2025 | HOL | Hoffman | Acquired via trade | CAP | | After |
| 7/18/2025 | HOL | Kelly,K | Traded away | CAP | | After |
| 7/18/2025 | HOL | Matos | Acquired via trade | CLE | | After |
| 7/18/2025 | HOL | Moncada | Acquired via trade | NHP | | After |
| 7/18/2025 | HOL | Murphy,S | Acquired via trade | CAP | | After |
| 7/18/2025 | HOL | Pages,P | Traded away | CAP | | After |
| 7/18/2025 | HOL | Pasquantino | Acquired via trade | CAP | | After |
| 7/18/2025 | HOL | Pauley | Acquired via trade | NDF | | After |
| 7/18/2025 | HOL | Ryan,Ri | Acquired via trade | CGS | | After |
| 7/18/2025 | HOL | Schneemann | Traded away | NDF | | After |
| 7/18/2025 | HOL | Smith,J | Traded away | NDF | | After |
| 7/18/2025 | HOL | Suzuki | Traded away | NHP | | After |
| 7/18/2025 | HOL | Urshela | Traded away | DUR | | After |
| 7/18/2025 | NDF | Foley | Traded away | HOL | | After |
| 7/18/2025 | NDF | Pauley | Traded away | HOL | | After |
| 7/18/2025 | NDF | Schneemann | Acquired via trade | HOL | | After |
| 7/18/2025 | NDF | Smith,J | Acquired via trade | HOL | | After |
| 7/18/2025 | NHP | Moncada | Traded away | HOL | | After |
| 7/18/2025 | NHP | Suzuki | Acquired via trade | HOL | | After |
| 7/19/2025 | CAP | Hanifee | Demoted to reserve roster | | | Before |
| 7/19/2025 | CED | Minter | Demoted to reserve roster | | | Before |
| 7/19/2025 | CED | Treinen | Promoted to active roster | | | Before |
| 7/19/2025 | CGS | Buxton | Activated from Injured List | | | Before |
| 7/19/2025 | CGS | McCray | Demoted to reserve roster | | | Before |
| 7/19/2025 | CLE | Foley | Demoted to reserve roster | | | Before |
| 7/19/2025 | CLE | Hicks,J | Demoted to reserve roster | | | Before |
| 7/19/2025 | CLE | Hill,D | Demoted to reserve roster | | | Before |
| 7/19/2025 | HOL | Brito | Demoted to reserve roster | | | Before |
| 7/19/2025 | HOL | Littell | Demoted to reserve roster | | | Before |
| 7/19/2025 | HOL | Means | Promoted to active roster | | | Before |
| 7/19/2025 | HOL | Moncada | Promoted to active roster | | | Before |
| 7/19/2025 | HOL | Ray | Promoted to active roster | | | Before |
| 7/19/2025 | HOL | Urias,L | Promoted to active roster | | | Before |
| 7/19/2025 | NDF | Arcia | Demoted to reserve roster | | | Before |
| 7/19/2025 | NDF | Brown,B | Demoted to reserve roster | | | Before |
| 7/19/2025 | NDF | Brown,B | Promoted to active roster | | | Before |
| 7/19/2025 | NDF | Butto | Promoted to active roster | | | Before |
| 7/19/2025 | NDF | Lopez,Jaco | Demoted to reserve roster | | | Before |
| 7/19/2025 | NDF | Schneemann | Promoted to active roster | | | Before |
| 7/19/2025 | NHP | Heyward | Demoted to reserve roster | | | Before |
| 7/19/2025 | PUE | Cleavinger | Promoted to active roster | | | Before |
| 7/19/2025 | PUE | Diaz,Yi | Demoted to reserve roster | | | Before |
| 7/19/2025 | PUE | Guenther | Demoted to reserve roster | | | Before |
| 7/19/2025 | PUE | Lovelady | Demoted to reserve roster | | | Before |
| 7/19/2025 | PUE | Lovelady | Promoted to active roster | | | Before |
| 7/19/2025 | PUE | Martin,A | Demoted to reserve roster | | | Before |
| 7/19/2025 | PUE | Schmidt | Activated from Injured List | | | Before |
| 7/19/2025 | PUE | Young,J | Promoted to active roster | | | Before |
| 7/19/2025 | SPR | Candelario | Activated from Injured List | | | Before |
| 7/19/2025 | SPR | Deluca | Promoted to active roster | | | Before |
| 7/19/2025 | SPR | Flores | Demoted to reserve roster | | | Before |
| 7/19/2025 | SPR | Meadows | Placed on Injured List | | 7/19/2025 | Before |
| 7/19/2025 | SPR | Shuster | Demoted to reserve roster | | | Before |
| 7/19/2025 | SPR | Thornton | Promoted to active roster | | | Before |
| 7/22/2025 | CAP | Pages,P | Demoted to reserve roster | | | Before |
| 7/22/2025 | CAP | Williams,G | Promoted to active roster | | | Before |
| 7/22/2025 | CGS | Buxton | Activated from Injured List | | | Before |
| 7/22/2025 | CGS | Jimenez,L | Demoted to reserve roster | | | Before |
| 7/22/2025 | CGS | Liberatore | Promoted to active roster | | | Before |
| 7/22/2025 | CGS | McCray | Demoted to reserve roster | | | Before |
| 7/22/2025 | DSP | Baty | Promoted to active roster | | | Before |
| 7/22/2025 | DSP | McCutchen | Placed on Injured List | | 7/18/2025 | Before |
| 7/22/2025 | HOL | Leiter,M | Promoted to active roster | | | Before |
| 7/22/2025 | HOL | Littell | Promoted to active roster | | | Before |
| 7/22/2025 | HOL | Murphy,S | Promoted to active roster | | | Before |
| 7/22/2025 | OLL | Ashcraft | Promoted to active roster | | | Before |
| 7/22/2025 | OLL | Bender | Promoted to active roster | | | Before |
| 7/22/2025 | OLL | Bubic | Demoted to reserve roster | | | Before |
| 7/22/2025 | OLL | Megill,Ty | Demoted to reserve roster | | | Before |
| 7/22/2025 | SPR | Benson | Promoted to active roster | | | Before |
| 7/22/2025 | SPR | Harris II | Placed on Injured List | | 7/21/2025 | Before |
| 7/25/2025 | DUR | Paddack | Promoted to active roster | | | Before |
| 7/25/2025 | DUR | Woods Richardso | Placed on Injured List | | 7/24/2025 | Before |
| 7/25/2025 | OLL | Brown,S | Promoted to active roster | | | Before |
| 7/25/2025 | OLL | Pham | Demoted to reserve roster | | | Before |
| 7/28/2025 | CHI | Bido | Demoted to reserve roster | | | Before |
| 7/28/2025 | CHI | Kershaw | Promoted to active roster | | | Before |
| 7/28/2025 | CHI | Leahy | Promoted to active roster | | | Before |
| 7/28/2025 | CHI | Turnbull | Demoted to reserve roster | | | Before |
| 7/28/2025 | DCM | Crawford,B | Promoted to active roster | | | Before |
| 7/28/2025 | DCM | Wade,T | Demoted to reserve roster | | | Before |
| 7/28/2025 | NHP | Coulombe | Demoted to reserve roster | | | Before |
| 7/28/2025 | NHP | Hamilton,I | Promoted to active roster | | | Before |
| 7/28/2025 | NHP | Nardi | Promoted to active roster | | | Before |
| 7/28/2025 | NHP | Scherzer | Promoted to active roster | | | Before |
| 7/28/2025 | NHP | Tinoco | Demoted to reserve roster | | | Before |
| 7/28/2025 | NHP | Waldron | Placed on Injured List | | 7/26/2025 | Before |
| 7/28/2025 | OLL | Berroa,P | Promoted to active roster | | | Before |
| 7/28/2025 | OLL | Johnson,P | Placed on Injured List | | 7/28/2025 | Before |
| 7/28/2025 | OLL | Staumont | Promoted to active roster | | | Before |
| 7/28/2025 | OLL | Weathers | Demoted to reserve roster | | | Before |
| 7/31/2025 | DSP | McCutchen | Activated from Injured List | | | Before |
| 7/31/2025 | DSP | Soriano,J | Demoted to reserve roster | | | Before |
| 7/31/2025 | RMH | Blackmon | Promoted to active roster | | | Before |
| 7/31/2025 | RMH | Calhoun | Activated from Injured List | | | Before |
| 7/31/2025 | RMH | Calhoun | Demoted to reserve roster | | | Before |
| 7/31/2025 | RMH | Friedl | Placed on Injured List | | 7/31/2025 | Before |
| 7/31/2025 | RMH | Gasser | Promoted to active roster | | | Before |
| 7/31/2025 | RMH | Ginkel | Demoted to reserve roster | | | Before |
| 7/31/2025 | RMH | Harris,H | Activated from Injured List | | | Before |
| 7/31/2025 | RMH | Sears | Demoted to reserve roster | | | Before |
| 8/3/2025 | AUR | Acuna,J | Promoted to active roster | | | Before |
| 8/3/2025 | AUR | Bradish | Promoted to active roster | | | Before |
| 8/3/2025 | AUR | Castillo,L | Demoted to reserve roster | | | Before |
| 8/3/2025 | AUR | Gore | Demoted to reserve roster | | | Before |
| 8/3/2025 | AUR | Javier | Demoted to reserve roster | | | Before |
| 8/3/2025 | AUR | Lockridge | Promoted to active roster | | | Before |
| 8/3/2025 | AUR | McKinstry | Demoted to reserve roster | | | Before |
| 8/3/2025 | AUR | Rosario,A | Activated from Injured List | | | Before |
| 8/3/2025 | NDF | Stallings | Activated from Injured List | | | Before |
| 8/3/2025 | NDF | Tatis | Placed on Injured List | | 7/29/2025 | Before |
| 8/3/2025 | OLL | Hurt | Promoted to active roster | | | Before |
| 8/3/2025 | OLL | Staumont | Demoted to reserve roster | | | Before |
| 8/3/2025 | PUE | Fry | Placed on Injured List | | 8/1/2025 | Before |
| 8/3/2025 | PUE | Schmitt | Promoted to active roster | | | Before |
| 8/3/2025 | SPR | Benson | Demoted to reserve roster | | | Before |
| 8/3/2025 | SPR | Meadows | Activated from Injured List | | | Before |
| 8/6/2025 | CUY | Acuna,R | Demoted to reserve roster | | | Before |
| 8/6/2025 | CUY | Arias | Demoted to reserve roster | | | Before |
| 8/6/2025 | CUY | Buehler | Demoted to reserve roster | | | Before |
| 8/6/2025 | CUY | Chaparro | Promoted to active roster | | | Before |
| 8/6/2025 | CUY | Garrett,B | Demoted to reserve roster | | | Before |
| 8/6/2025 | CUY | Hurter | Promoted to active roster | | | Before |
| 8/6/2025 | CUY | Kelly,Me | Activated from Injured List | | | Before |
| 8/6/2025 | CUY | Lukes | Promoted to active roster | | | Before |
| 8/6/2025 | CUY | Marchan | Demoted to reserve roster | | | Before |
| 8/6/2025 | CUY | Marinaccio | Promoted to active roster | | | Before |
| 8/6/2025 | CUY | Palencia | Demoted to reserve roster | | | Before |
| 8/6/2025 | CUY | Poche | Demoted to reserve roster | | | Before |
| 8/6/2025 | CUY | Tromp | Promoted to active roster | | | Before |
| 8/6/2025 | CUY | Wilson,W | Promoted to active roster | | | Before |
| 8/6/2025 | HOL | Holderman | Promoted to active roster | | | Before |
| 8/6/2025 | HOL | Sanchez,J | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Brown,B | Promoted to active roster | | | Before |
| 8/6/2025 | NDF | Francis | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Herz | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Millas | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Musgrove | Promoted to active roster | | | Before |
| 8/6/2025 | NDF | Schneemann | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Thompson,K | Promoted to active roster | | | Before |
| 8/6/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 8/9/2025 | AUR | Acuna,J | Demoted to reserve roster | | | Before |
| 8/9/2025 | AUR | Bigge | Promoted to active roster | | | Before |
| 8/9/2025 | AUR | Castillo,L | Promoted to active roster | | | Before |
| 8/9/2025 | AUR | Duvall | Demoted to reserve roster | | | Before |
| 8/9/2025 | AUR | Gore | Promoted to active roster | | | Before |
| 8/9/2025 | AUR | Zeferjahn | Demoted to reserve roster | | | Before |
| 8/12/2025 | OLL | Berroa,P | Demoted to reserve roster | | | Before |
| 8/12/2025 | OLL | Johnson,P | Activated from Injured List | | | Before |
| 8/12/2025 | SPR | Deluca | Demoted to reserve roster | | | Before |
| 8/12/2025 | SPR | Harris II | Activated from Injured List | | | Before |
| 8/15/2025 | AUR | Conine | Demoted to reserve roster | | | Before |
| 8/15/2025 | AUR | Zeferjahn | Promoted to active roster | | | Before |
| 8/15/2025 | DUR | Cabrera,E | Placed on Injured List | | 8/13/2025 | Before |
| 8/15/2025 | DUR | Woods Richardso | Activated from Injured List | | | Before |
| 8/15/2025 | NDF | Brown,B | Demoted to reserve roster | | | Before |
| 8/15/2025 | NDF | Cousins | Demoted to reserve roster | | | Before |
| 8/15/2025 | NDF | Francis | Promoted to active roster | | | Before |
| 8/15/2025 | NDF | Lopez,Jaco | Promoted to active roster | | | Before |
| 8/15/2025 | NHP | Fitzgerald | Demoted to reserve roster | | | Before |
| 8/15/2025 | NHP | Grisham | Promoted to active roster | | | Before |
| 8/15/2025 | NHP | Madrigal | Promoted to active roster | | | Before |
| 8/15/2025 | NHP | Robles | Demoted to reserve roster | | | Before |
| 8/15/2025 | NHP | Scherzer | Demoted to reserve roster | | | Before |
| 8/15/2025 | NHP | Waldron | Activated from Injured List | | | Before |
| 8/15/2025 | OLL | Hendricks | Promoted to active roster | | | Before |
| 8/15/2025 | OLL | Hurt | Demoted to reserve roster | | | Before |
| 8/15/2025 | OLL | Skubal | Placed on Injured List | | 8/14/2025 | Before |
| 8/15/2025 | OLL | Staumont | Promoted to active roster | | | Before |
| 8/18/2025 | AUR | Duvall | Promoted to active roster | | | Before |
| 8/18/2025 | AUR | Zeferjahn | Demoted to reserve roster | | | Before |
| 8/18/2025 | NHP | deGrom | Promoted to active roster | | | Before |
| 8/18/2025 | NHP | Lopez,R | Placed on Injured List | | 8/16/2025 | Before |
| 8/18/2025 | OLL | Caratini | Placed on Injured List | | 8/15/2025 | Before |
| 8/18/2025 | OLL | Iriarte | Promoted to active roster | | | Before |
| 8/18/2025 | OLL | Jackson,A | Promoted to active roster | | | Before |
| 8/18/2025 | OLL | Staumont | Demoted to reserve roster | | | Before |
| 8/21/2025 | AUR | Duvall | Demoted to reserve roster | | | Before |
| 8/21/2025 | AUR | Duvall | Promoted to active roster | | | Before |
| 8/21/2025 | AUR | Lockridge | Demoted to reserve roster | | | Before |
| 8/21/2025 | AUR | Zeferjahn | Promoted to active roster | | | Before |
| 8/21/2025 | CED | Halvorsen | Promoted to active roster | | | Before |
| 8/21/2025 | CED | Hernandez,D | Demoted to reserve roster | | | Before |
| 8/21/2025 | DSP | Darvish | Promoted to active roster | | | Before |
| 8/21/2025 | DSP | McCutchen | Placed on Injured List | | 8/21/2025 | Before |
| 8/21/2025 | DSP | Morgan | Placed on Injured List | | 8/20/2025 | Before |
| 8/21/2025 | DSP | Soriano,J | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Aldegheri | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Bellinger | Placed on Injured List | | 8/20/2025 | Before |
| 8/21/2025 | NDF | Contreras,WE | Activated from Injured List | | | Before |
| 8/21/2025 | NDF | Loperfido | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Lopez,Jaco | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | McDonald | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Millas | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Millas | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Sanchez,G | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Schneemann | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Schneemann | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Thompson,K | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Wagner | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 8/21/2025 | OLL | Berroa,P | Promoted to active roster | | | Before |
| 8/21/2025 | OLL | Megill,Tr | Demoted to reserve roster | | | Before |
| 8/21/2025 | RMH | Bassitt | Demoted to reserve roster | | | Before |
| 8/21/2025 | RMH | Florial | Promoted to active roster | | | Before |
| 8/21/2025 | RMH | Friedl | Activated from Injured List | | | Before |
| 8/21/2025 | RMH | Friedl | Demoted to reserve roster | | | Before |
| 8/21/2025 | RMH | Gasser | Demoted to reserve roster | | | Before |
| 8/21/2025 | RMH | Ginkel | Promoted to active roster | | | Before |
| 8/21/2025 | RMH | Junis | Demoted to reserve roster | | | Before |
| 8/21/2025 | RMH | Sears | Promoted to active roster | | | Before |
| 8/21/2025 | TOR | Suter | Demoted to reserve roster | | | Before |
| 8/21/2025 | TOR | Uceta | Promoted to active roster | | | Before |
| 8/24/2025 | CED | Birdsong | Promoted to active roster | | | Before |
| 8/24/2025 | CED | Lynch | Demoted to reserve roster | | | Before |
| 8/24/2025 | CLE | Alexander,S | Demoted to reserve roster | | | Before |
| 8/24/2025 | CLE | Foley | Promoted to active roster | | | Before |
| 8/24/2025 | CLE | Hicks,J | Promoted to active roster | | | Before |
| 8/24/2025 | CLE | Hill,D | Promoted to active roster | | | Before |
| 8/24/2025 | CLE | Iglesias,J | Demoted to reserve roster | | | Before |
| 8/24/2025 | CLE | Rocchio | Promoted to active roster | | | Before |
| 8/24/2025 | CLE | Skenes | Demoted to reserve roster | | | Before |
| 8/24/2025 | CLE | Snider | Demoted to reserve roster | | | Before |
| 8/24/2025 | CLE | Snider | Promoted to active roster | | | Before |
| 8/24/2025 | CLE | Wade,L | Demoted to reserve roster | | | Before |
| 8/24/2025 | DUR | Aranda | Demoted to reserve roster | | | Before |
| 8/24/2025 | DUR | Cabrera,E | Activated from Injured List | | | Before |
| 8/24/2025 | DUR | Cameron | Promoted to active roster | | | Before |
| 8/24/2025 | DUR | Paddack | Demoted to reserve roster | | | Before |
| 8/24/2025 | DUR | Urshela | Promoted to active roster | | | Before |
| 8/24/2025 | DUR | Yelich | Demoted to reserve roster | | | Before |
| 8/24/2025 | NDF | Contreras,WE | Placed on Injured List | | 8/23/2025 | Before |
| 8/24/2025 | NDF | Millas | Promoted to active roster | | | Before |
| 8/24/2025 | OLL | Berroa,P | Demoted to reserve roster | | | Before |
| 8/24/2025 | OLL | Skubal | Activated from Injured List | | | Before |
| 8/24/2025 | RMH | Bassitt | Promoted to active roster | | | Before |
| 8/24/2025 | RMH | Mize | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Alvarez,Y | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Betts | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Goodman | Promoted to active roster | | | Before |
| 8/24/2025 | TOR | Greene,H | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Keith | Promoted to active roster | | | Before |
| 8/24/2025 | TOR | Manoah | Promoted to active roster | | | Before |
| 8/24/2025 | TOR | Pepiot | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Rodriguez,E | Promoted to active roster | | | Before |
| 8/27/2025 | AUR | Acuna,J | Promoted to active roster | | | Before |
| 8/27/2025 | AUR | Blanco,D | Demoted to reserve roster | | | Before |
| 8/27/2025 | AUR | Blanco,D | Promoted to active roster | | | Before |
| 8/27/2025 | AUR | Devers,R | Placed on Injured List | | 8/23/2025 | Before |
| 8/27/2025 | AUR | Rodriguez,Ya | Promoted to active roster | | | Before |
| 8/27/2025 | AUR | Zeferjahn | Demoted to reserve roster | | | Before |
| 8/27/2025 | CAP | Caminero | Promoted to active roster | | | Before |
| 8/27/2025 | CAP | Rodriguez,M | Demoted to reserve roster | | | Before |
| 8/27/2025 | CED | Fitts | Promoted to active roster | | | Before |
| 8/27/2025 | CED | Hampson | Demoted to reserve roster | | | Before |
| 8/27/2025 | CED | Mlodzinski | Promoted to active roster | | | Before |
| 8/27/2025 | CED | Nunez,N | Promoted to active roster | | | Before |
| 8/27/2025 | CED | Quantrill | Demoted to reserve roster | | | Before |
| 8/27/2025 | CED | Voth | Demoted to reserve roster | | | Before |
| 8/27/2025 | CGS | Povich | Promoted to active roster | | | Before |
| 8/27/2025 | CGS | Slaten | Demoted to reserve roster | | | Before |
| 8/27/2025 | CUY | Andujar | Demoted to reserve roster | | | Before |
| 8/27/2025 | CUY | Arias | Promoted to active roster | | | Before |
| 8/27/2025 | CUY | Clase,J | Promoted to active roster | | | Before |
| 8/27/2025 | CUY | Garrett,B | Promoted to active roster | | | Before |
| 8/27/2025 | CUY | Hurter | Demoted to reserve roster | | | Before |
| 8/27/2025 | CUY | Jacob | Promoted to active roster | | | Before |
| 8/27/2025 | CUY | Kelly,Me | Placed on Injured List | | 8/27/2025 | Before |
| 8/27/2025 | CUY | Lukes | Demoted to reserve roster | | | Before |
| 8/27/2025 | CUY | Marinaccio | Demoted to reserve roster | | | Before |
| 8/27/2025 | CUY | Myers,D | Demoted to reserve roster | | | Before |
| 8/27/2025 | CUY | Palencia | Promoted to active roster | | | Before |
| 8/27/2025 | CUY | Thomas,A | Promoted to active roster | | | Before |
| 8/27/2025 | NHP | deGrom | Demoted to reserve roster | | | Before |
| 8/27/2025 | NHP | Scherzer | Promoted to active roster | | | Before |
| 8/27/2025 | OLL | Caratini | Activated from Injured List | | | Before |
| 8/27/2025 | OLL | Jackson,A | Demoted to reserve roster | | | Before |
| 8/27/2025 | RMH | Bassitt | Demoted to reserve roster | | | Before |
| 8/27/2025 | RMH | Brazoban | Demoted to reserve roster | | | Before |
| 8/27/2025 | RMH | Florial | Demoted to reserve roster | | | Before |
| 8/27/2025 | RMH | Junis | Promoted to active roster | | | Before |
| 8/27/2025 | RMH | Mize | Promoted to active roster | | | Before |
| 8/27/2025 | RMH | Wilson,B | Promoted to active roster | | | Before |
| 8/30/2025 | AUR | Lockridge | Promoted to active roster | | | Before |
| 8/30/2025 | AUR | Lodolo | Demoted to reserve roster | | | Before |
| 8/30/2025 | CAP | Cobb | Promoted to active roster | | | Before |
| 8/30/2025 | CAP | Eflin | Demoted to reserve roster | | | Before |
| 8/30/2025 | CAP | Hall | Promoted to active roster | | | Before |
| 8/30/2025 | CAP | Schwellenbach | Demoted to reserve roster | | | Before |
| 8/30/2025 | CLE | Hicks,J | Demoted to reserve roster | | | Before |
| 8/30/2025 | CLE | Kiner-Falefa | Placed on Injured List | | 8/30/2025 | Before |
| 8/30/2025 | CLE | Skenes | Promoted to active roster | | | Before |
| 8/30/2025 | CLE | Wade,L | Promoted to active roster | | | Before |
| 8/30/2025 | HOL | Baez | Promoted to active roster | | | Before |
| 8/30/2025 | HOL | Dunn,O | Promoted to active roster | | | Before |
| 8/30/2025 | HOL | Hernandez,En | Placed on Injured List | | 8/28/2025 | Before |
| 8/30/2025 | HOL | Pasquantino | Placed on Injured List | | 8/30/2025 | Before |
| 8/30/2025 | PUE | Brujan | Demoted to reserve roster | | | Before |
| 8/30/2025 | PUE | Cleavinger | Demoted to reserve roster | | | Before |
| 8/30/2025 | PUE | Ferrer | Promoted to active roster | | | Before |
| 8/30/2025 | PUE | Fry | Activated from Injured List | | | Before |
| 8/30/2025 | PUE | Lewis | Demoted to reserve roster | | | Before |
| 8/30/2025 | PUE | Sogard | Promoted to active roster | | | Before |
| 9/2/2025 | AUR | Blanco,D | Demoted to reserve roster | | | Before |
| 9/2/2025 | AUR | Blanco,D | Promoted to active roster | | | Before |
| 9/2/2025 | AUR | Castillo,L | Demoted to reserve roster | | | Before |
| 9/2/2025 | AUR | Gore | Demoted to reserve roster | | | Before |
| 9/2/2025 | AUR | Gore | Promoted to active roster | | | Before |
| 9/2/2025 | AUR | Lodolo | Promoted to active roster | | | Before |
| 9/2/2025 | CAP | Cobb | Demoted to reserve roster | | | Before |
| 9/2/2025 | CAP | Eflin | Promoted to active roster | | | Before |
| 9/2/2025 | CAP | Pfaadt | Promoted to active roster | | | Before |
| 9/2/2025 | CAP | Ryan,J | Demoted to reserve roster | | | Before |
| 9/2/2025 | CAP | Schwellenbach | Promoted to active roster | | | Before |
| 9/2/2025 | CAP | Tucker,K | Demoted to reserve roster | | | Before |
| 9/2/2025 | RMH | Bassitt | Promoted to active roster | | | Before |
| 9/2/2025 | RMH | Jansen,D | Demoted to reserve roster | | | Before |
| 9/2/2025 | RMH | Mize | Demoted to reserve roster | | | Before |
| 9/2/2025 | RMH | Sabol | Promoted to active roster | | | Before |
| 9/5/2025 | AUR | Blanco,D | Promoted to active roster | | | Before |
| 9/5/2025 | AUR | Castillo,L | Promoted to active roster | | | Before |
| 9/5/2025 | AUR | Conine | Promoted to active roster | | | Before |
| 9/5/2025 | AUR | Lodolo | Demoted to reserve roster | | | Before |
| 9/5/2025 | AUR | Ortiz,LL | Demoted to reserve roster | | | Before |
| 9/5/2025 | AUR | Yepez | Placed on Injured List | | 9/4/2025 | Before |
| 9/5/2025 | CAP | Pages,P | Promoted to active roster | | | Before |
| 9/5/2025 | CAP | Schwellenbach | Demoted to reserve roster | | | Before |
| 9/5/2025 | CUY | Arias | Demoted to reserve roster | | | Before |
| 9/5/2025 | CUY | Garrett,S | Promoted to active roster | | | Before |
| 9/5/2025 | CUY | Jacob | Demoted to reserve roster | | | Before |
| 9/5/2025 | CUY | Loaisiga | Promoted to active roster | | | Before |
| 9/5/2025 | CUY | Marchan | Promoted to active roster | | | Before |
| 9/5/2025 | CUY | Moreno | Placed on Injured List | | 9/3/2025 | Before |
| 9/5/2025 | CUY | Poche | Promoted to active roster | | | Before |
| 9/5/2025 | CUY | Wilson,W | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Boyle | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Brieske | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | German | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Gil | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Knack | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | McCann,K | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Raleigh | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Rea | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Soler | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Soriano,J | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Stanek | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Suwinski | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Woodford | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Yamamoto | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Young,D | Promoted to active roster | | | Before |
| 9/5/2025 | HOL | Bellozo | Promoted to active roster | | | Before |
| 9/5/2025 | HOL | Brito | Promoted to active roster | | | Before |
| 9/5/2025 | HOL | Contreras,WJ | Demoted to reserve roster | | | Before |
| 9/5/2025 | HOL | Dubin | Promoted to active roster | | | Before |
| 9/5/2025 | HOL | Fried | Demoted to reserve roster | | | Before |
| 9/5/2025 | HOL | Hoffman | Demoted to reserve roster | | | Before |
| 9/5/2025 | HOL | Kochanowicz | Promoted to active roster | | | Before |
| 9/5/2025 | HOL | Matos | Promoted to active roster | | | Before |
| 9/5/2025 | HOL | Murphy,S | Demoted to reserve roster | | | Before |
| 9/5/2025 | HOL | Pauley | Promoted to active roster | | | Before |
| 9/5/2025 | HOL | Pivetta | Demoted to reserve roster | | | Before |
| 9/5/2025 | HOL | Ragans | Demoted to reserve roster | | | Before |
| 9/5/2025 | HOL | Rodriguez,R | Promoted to active roster | | | Before |
| 9/5/2025 | HOL | Rogers,Ty | Demoted to reserve roster | | | Before |
| 9/5/2025 | HOL | Rooker | Demoted to reserve roster | | | Before |
| 9/5/2025 | HOL | Sanchez,J | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Carlson | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Cecconi | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Dezenzo | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Hamilton,I | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | Kwan | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | McDermott | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Nardi | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | Nelson,R | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | Nunez,D | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | Rizzo | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Strider | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Suzuki | Demoted to reserve roster | | | Before |
| 9/5/2025 | OLL | Berroa,P | Promoted to active roster | | | Before |
| 9/5/2025 | OLL | Pallante | Demoted to reserve roster | | | Before |
| 9/8/2025 | AUR | Bader | Demoted to reserve roster | | | Before |
| 9/8/2025 | AUR | Blanco,D | Demoted to reserve roster | | | Before |
| 9/8/2025 | AUR | Conine | Demoted to reserve roster | | | Before |
| 9/8/2025 | AUR | Devers,R | Activated from Injured List | | | Before |
| 9/8/2025 | AUR | Lockridge | Demoted to reserve roster | | | Before |
| 9/8/2025 | AUR | Lodolo | Promoted to active roster | | | Before |
| 9/8/2025 | AUR | Ortiz,LL | Promoted to active roster | | | Before |
| 9/8/2025 | AUR | Zeferjahn | Promoted to active roster | | | Before |
| 9/8/2025 | CED | Carpenter,K | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Fitts | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Halvorsen | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Hampson | Promoted to active roster | | | Before |
| 9/8/2025 | CED | Hernandez,C | Promoted to active roster | | | Before |
| 9/8/2025 | CED | Madden | Promoted to active roster | | | Before |
| 9/8/2025 | CED | Treinen | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Voth | Promoted to active roster | | | Before |
| 9/11/2025 | CAP | Cobb | Promoted to active roster | | | Before |
| 9/11/2025 | CAP | Dominguez,J | Promoted to active roster | | | Before |
| 9/11/2025 | CAP | Eflin | Demoted to reserve roster | | | Before |
| 9/11/2025 | CAP | Eovaldi | Demoted to reserve roster | | | Before |
| 9/11/2025 | CAP | Herrera,I | Demoted to reserve roster | | | Before |
| 9/11/2025 | CAP | Kelly,Mi | Promoted to active roster | | | Before |
| 9/11/2025 | CAP | King,M | Demoted to reserve roster | | | Before |
| 9/11/2025 | CAP | Langford | Demoted to reserve roster | | | Before |
| 9/11/2025 | CAP | Lee,J | Promoted to active roster | | | Before |
| 9/11/2025 | CAP | Rodriguez,M | Promoted to active roster | | | Before |
| 9/11/2025 | CGS | Jimenez,L | Promoted to active roster | | | Before |
| 9/11/2025 | CGS | Yoshida | Placed on Injured List | | 9/9/2025 | Before |
| 9/11/2025 | HOL | Martinez,J | Demoted to reserve roster | | | Before |
| 9/11/2025 | HOL | Rodriguez,Ju | Demoted to reserve roster | | | Before |
| 9/11/2025 | HOL | Ryan,Ri | Promoted to active roster | | | Before |
| 9/11/2025 | HOL | Swanson,D | Demoted to reserve roster | | | Before |
| 9/11/2025 | HOL | Thaiss | Promoted to active roster | | | Before |
| 9/11/2025 | HOL | Whitley | Promoted to active roster | | | Before |