| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/8/2025 | SPR | Candelario | Placed on Injured List | | 4/6/2025 | Before |
| 4/8/2025 | SPR | Flores | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Amaya,M | Placed on Injured List | | 4/7/2025 | Before |
| 4/8/2025 | TOR | Bednar | Demoted to reserve roster | | | Before |
| 4/8/2025 | TOR | Bednar | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Bednar | Demoted to reserve roster | | | Before |
| 4/8/2025 | TOR | Betts | Placed on Injured List | | 4/7/2025 | Before |
| 4/8/2025 | TOR | Goodman | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Greene,H | Placed on Injured List | | 4/8/2025 | Before |
| 4/8/2025 | TOR | Keith | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Rodriguez,E | Demoted to reserve roster | | | Before |
| 4/8/2025 | TOR | Rodriguez,E | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Rodriguez,E | Promoted to active roster | | | Before |
| 4/8/2025 | TOR | Suter | Promoted to active roster | | | Before |
| 4/14/2025 | NHP | deGrom | Signed | | | Before |
| 4/17/2025 | SPR | Deluca | Promoted to active roster | | | Before |
| 4/17/2025 | SPR | Harris II | Placed on Injured List | | 4/17/2025 | Before |
| 4/20/2025 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 4/20/2025 | DSP | Knack | Promoted to active roster | | | Before |
| 4/20/2025 | DSP | Rea | Promoted to active roster | | | Before |
| 4/20/2025 | DSP | Yamamoto | Demoted to reserve roster | | | Before |
| 4/20/2025 | NHP | Nelson,R | Placed on Injured List | | 4/18/2025 | Before |
| 4/23/2025 | NHP | Lopez,R | Placed on Injured List | | 4/21/2025 | Before |
| 4/23/2025 | NHP | Scherzer | Promoted to active roster | | | Before |
| 4/23/2025 | TOR | Amaya,M | Activated from Injured List | | | Before |
| 4/23/2025 | TOR | Bednar | Promoted to active roster | | | Before |
| 4/23/2025 | TOR | Betts | Activated from Injured List | | | Before |
| 4/23/2025 | TOR | Crow-Armstrong | Demoted to reserve roster | | | Before |
| 4/23/2025 | TOR | Goodman | Demoted to reserve roster | | | Before |
| 4/23/2025 | TOR | Greene,H | Activated from Injured List | | | Before |
| 4/23/2025 | TOR | Rodriguez,E | Demoted to reserve roster | | | Before |
| 4/23/2025 | TOR | Uceta | Demoted to reserve roster | | | Before |
| 4/26/2025 | DSP | Darvish | Promoted to active roster | | | Before |
| 4/26/2025 | DSP | Knack | Demoted to reserve roster | | | Before |
| 4/26/2025 | DSP | Morgan | Demoted to reserve roster | | | Before |
| 4/26/2025 | DSP | Stanek | Promoted to active roster | | | Before |
| 4/26/2025 | NDF | Lively | Signed | | | Before |
| 4/26/2025 | NDF | Stowers | Released | | | Before |
| 4/26/2025 | NDF | Stowers | Released | | | Before |
| 4/26/2025 | NDF | Stowers | Released | | | Before |
| 4/26/2025 | NDF | Stowers | Signed | | | Before |
| 4/26/2025 | NDF | Stowers | Signed | | | Before |
| 4/26/2025 | NDF | Stowers | Signed | | | Before |
| 4/26/2025 | NDF | Stowers | Signed | | | Before |
| 4/26/2025 | NDF | Stripling | Signed | | | Before |
| 5/2/2025 | DSP | McCutchen | Placed on Injured List | | 5/2/2025 | Before |
| 5/2/2025 | DSP | Suwinski | Promoted to active roster | | | Before |
| 5/2/2025 | NHP | deGrom | Demoted to reserve roster | | | Before |
| 5/2/2025 | NHP | Lopez,R | Activated from Injured List | | | Before |
| 5/5/2025 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 5/5/2025 | DSP | Yamamoto | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Aldegheri | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Aldegheri | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Amaya,J | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Amaya,J | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Beeter | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Beeter | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Bellinger | Placed on Injured List | | 4/25/2025 | Before |
| 5/5/2025 | NDF | Brown,B | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Butto | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Chargois | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Feduccia | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Feduccia | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Foley | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | LeMahieu | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | LeMahieu | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Loperfido | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Lopez,Jaco | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Lopez,Jaco | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Malloy | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Matz | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Matz | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | McDonald | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | McDonald | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Millas | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Millas | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Musgrove | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Myers,D | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Pauley | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Pauley | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Pereda | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Pereda | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Phillips,E | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Rendon | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Rendon | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Shenton | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Shenton | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Stowers | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Stripling | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Thompson,K | Promoted to active roster | | | Before |
| 5/5/2025 | NDF | Wagner | Demoted to reserve roster | | | Before |
| 5/5/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 5/5/2025 | TOR | Bednar | Demoted to reserve roster | | | Before |
| 5/5/2025 | TOR | Brown,H | Placed on Injured List | | 4/30/2025 | Before |
| 5/5/2025 | TOR | Rodriguez,E | Promoted to active roster | | | Before |
| 5/5/2025 | TOR | Uceta | Promoted to active roster | | | Before |
| 5/8/2025 | SPR | Candelario | Activated from Injured List | | | Before |
| 5/8/2025 | SPR | Deluca | Demoted to reserve roster | | | Before |
| 5/8/2025 | SPR | Flores | Demoted to reserve roster | | | Before |
| 5/8/2025 | SPR | Harris II | Activated from Injured List | | | Before |
| 5/11/2025 | SPR | Imanaga | Placed on Injured List | | 5/11/2025 | Before |
| 5/11/2025 | SPR | Shuster | Signed | | | Before |
| 5/11/2025 | TOR | Crow-Armstrong | Promoted to active roster | | | Before |
| 5/11/2025 | TOR | Manoah | Promoted to active roster | | | Before |
| 5/11/2025 | TOR | McCarthy | Placed on Injured List | | 5/9/2025 | Before |
| 5/11/2025 | TOR | Rodriguez,E | Demoted to reserve roster | | | Before |
| 5/14/2025 | NHP | Nelson,R | Activated from Injured List | | | Before |
| 5/14/2025 | NHP | Scherzer | Demoted to reserve roster | | | Before |
| 5/14/2025 | TOR | Bednar | Promoted to active roster | | | Before |
| 5/14/2025 | TOR | Manoah | Demoted to reserve roster | | | Before |
| 5/14/2025 | TOR | Manoah | Promoted to active roster | | | Before |
| 5/14/2025 | TOR | Manoah | Demoted to reserve roster | | | Before |
| 5/14/2025 | TOR | Young,D | Demoted to reserve roster | | | Before |
| 5/14/2025 | TOR | Young,D | Promoted to active roster | | | Before |
| 5/17/2025 | DSP | McCutchen | Activated from Injured List | | | Before |
| 5/17/2025 | DSP | Suwinski | Demoted to reserve roster | | | Before |
| 5/17/2025 | NHP | Grisham | Promoted to active roster | | | Before |
| 5/17/2025 | NHP | Robles | Placed on Injured List | | 5/15/2025 | Before |
| 5/20/2025 | CED | McGuire | Placed on Injured List | | 5/18/2025 | Before |
| 5/20/2025 | CED | Torrens | Promoted to active roster | | | Before |
| 5/20/2025 | TOR | Brown,H | Activated from Injured List | | | Before |
| 5/20/2025 | TOR | Uceta | Demoted to reserve roster | | | Before |
| 5/23/2025 | DSP | Scott,Tan | Released | | | Before |
| 5/23/2025 | DSP | Scott,Tan | Signed | | | Before |
| 5/23/2025 | DSP | Scott,Tan | Signed | | | Before |
| 5/23/2025 | DSP | Stanek | Demoted to reserve roster | | | Before |
| 5/23/2025 | NDF | Bellinger | Activated from Injured List | | | Before |
| 5/23/2025 | NDF | Malloy | Demoted to reserve roster | | | Before |
| 5/23/2025 | SPR | McCann,J | Placed on Injured List | | 5/23/2025 | Before |
| 5/23/2025 | SPR | Vazquez,C | Signed | | | Before |
| 5/23/2025 | TOR | Crow-Armstrong | Demoted to reserve roster | | | Before |
| 5/23/2025 | TOR | McCarthy | Activated from Injured List | | | Before |
| 5/23/2025 | TOR | Uceta | Promoted to active roster | | | Before |
| 5/23/2025 | TOR | Young,D | Demoted to reserve roster | | | Before |
| 5/26/2025 | SPR | Imanaga | Activated from Injured List | | | Before |
| 5/26/2025 | SPR | Thornton | Demoted to reserve roster | | | Before |
| 5/29/2025 | NDF | Brown,B | Demoted to reserve roster | | | Before |
| 5/29/2025 | NDF | Chargois | Promoted to active roster | | | Before |
| 5/29/2025 | NDF | Foley | Promoted to active roster | | | Before |
| 5/29/2025 | NDF | Musgrove | Promoted to active roster | | | Before |
| 5/29/2025 | NDF | Myers,D | Demoted to reserve roster | | | Before |
| 5/29/2025 | NDF | Phillips,E | Promoted to active roster | | | Before |
| 5/29/2025 | NDF | Puk | Placed on Injured List | | 5/25/2025 | Before |
| 5/29/2025 | NDF | Williams,T | Placed on Injured List | | 5/17/2025 | Before |
| 5/29/2025 | NHP | Grisham | Demoted to reserve roster | | | Before |
| 5/29/2025 | NHP | Robles | Activated from Injured List | | | Before |
| 5/31/2025 | NDF | Bibee | Acquired via trade | CUY | | After |
| 5/31/2025 | NDF | Chapman,A | Acquired via trade | CUY | | After |
| 5/31/2025 | NDF | Lively | Traded away | CUY | | After |
| 5/31/2025 | NDF | Myers,D | Traded away | CUY | | After |
| 5/31/2025 | NDF | Rendon | Traded away | CUY | | After |
| 5/31/2025 | NDF | Stowers | Traded away | CUY | | After |
| 5/31/2025 | NDF | Stripling | Traded away | CUY | | After |
| 6/1/2025 | NDF | Brown,B | Promoted to active roster | | | Before |
| 6/1/2025 | NDF | Chargois | Demoted to reserve roster | | | Before |
| 6/1/2025 | NDF | Musgrove | Demoted to reserve roster | | | Before |
| 6/1/2025 | NDF | Phillips,E | Demoted to reserve roster | | | Before |
| 6/1/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 6/7/2025 | NDF | Foley | Demoted to reserve roster | | | Before |
| 6/7/2025 | NDF | Puk | Activated from Injured List | | | Before |
| 6/7/2025 | NDF | Thompson,K | Demoted to reserve roster | | | Before |
| 6/7/2025 | NDF | Thompson,K | Promoted to active roster | | | Before |
| 6/7/2025 | NDF | Wagner | Demoted to reserve roster | | | Before |
| 6/7/2025 | NDF | Williams,T | Activated from Injured List | | | Before |
| 6/13/2025 | DSP | Darvish | Promoted to active roster | | | Before |
| 6/13/2025 | DSP | Yamamoto | Demoted to reserve roster | | | Before |
| 6/16/2025 | SPR | McCann,J | Activated from Injured List | | | Before |
| 6/16/2025 | SPR | Vazquez,C | Demoted to reserve roster | | | Before |
| 6/18/2025 | HAV | Canha | Traded away | CGS | | After |
| 6/18/2025 | HAV | Harrison | Acquired via trade | CGS | | After |
| 6/18/2025 | HAV | Hiura | Traded away | CGS | | After |
| 6/18/2025 | HAV | Kelly,Z | Traded away | CGS | | After |
| 6/18/2025 | HAV | Moore,M | Traded away | CGS | | After |
| 6/18/2025 | HAV | Pearson | Traded away | CGS | | After |
| 6/18/2025 | HAV | Realmuto | Traded away | CGS | | After |
| 6/18/2025 | HAV | Trout | Acquired via trade | CGS | | After |
| 6/18/2025 | HAV | Valdez,E | Traded away | CGS | | After |
| 6/19/2025 | DSP | Morgan | Promoted to active roster | | | Before |
| 6/19/2025 | DSP | Rea | Demoted to reserve roster | | | Before |
| 6/21/2025 | HAV | Bell | Acquired via trade | OLL | | After |
| 6/21/2025 | HAV | Clemens | Acquired via trade | OLL | | After |
| 6/21/2025 | HAV | Marsh,A | Traded away | OLL | | After |
| 6/21/2025 | HAV | Pham | Traded away | OLL | | After |
| 6/21/2025 | HAV | Stubbs | Acquired via trade | OLL | | After |
| 6/22/2025 | CED | Birdsong | Demoted to reserve roster | | | Before |
| 6/22/2025 | CED | Hernandez,C | Demoted to reserve roster | | | Before |
| 6/22/2025 | CED | Hernandez,D | Promoted to active roster | | | Before |
| 6/22/2025 | CED | Lynch | Promoted to active roster | | | Before |
| 6/22/2025 | HAV | Guerrero,L | Demoted to reserve roster | | | Before |
| 6/22/2025 | HAV | Harrison | Promoted to active roster | | | Before |
| 6/22/2025 | HAV | Stubbs | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Corbin | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Freeland | Placed on Injured List | | 6/24/2025 | Before |
| 6/25/2025 | CED | Halvorsen | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Joe | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Mlodzinski | Demoted to reserve roster | | | Before |
| 6/25/2025 | CED | Romero | Promoted to active roster | | | Before |
| 6/25/2025 | CED | Toglia | Demoted to reserve roster | | | Before |
| 6/25/2025 | CED | Treinen | Demoted to reserve roster | | | Before |
| 6/25/2025 | NHP | Grisham | Promoted to active roster | | | Before |
| 6/25/2025 | NHP | Robles | Placed on Injured List | | 6/24/2025 | Before |
| 6/25/2025 | TOR | Uceta | Demoted to reserve roster | | | Before |
| 6/25/2025 | TOR | Young,D | Promoted to active roster | | | Before |
| 7/1/2025 | CED | Baker,L | Promoted to active roster | | | Before |
| 7/1/2025 | CED | Carpenter,K | Demoted to reserve roster | | | Before |
| 7/1/2025 | CED | Fitts | Promoted to active roster | | | Before |
| 7/1/2025 | CED | Hays | Demoted to reserve roster | | | Before |
| 7/1/2025 | CED | Lynch | Placed on Injured List | | 6/28/2025 | Before |
| 7/1/2025 | CED | McGuire | Activated from Injured List | | | Before |
| 7/1/2025 | CED | McGuire | Demoted to reserve roster | | | Before |
| 7/1/2025 | CED | Toglia | Promoted to active roster | | | Before |
| 7/3/2025 | CED | Minter | Acquired via trade | HOL | | After |
| 7/3/2025 | DSP | Hilliard | Traded away | TOR | | After |
| 7/3/2025 | DSP | McCarthy | Acquired via trade | TOR | | After |
| 7/3/2025 | DSP | Walker,R | Traded away | TOR | | After |
| 7/3/2025 | DSP | Woodford | Acquired via trade | TOR | | After |
| 7/3/2025 | DSP | Young,D | Acquired via trade | TOR | | After |
| 7/3/2025 | TOR | Hilliard | Acquired via trade | DSP | | After |
| 7/3/2025 | TOR | McCarthy | Traded away | DSP | | After |
| 7/3/2025 | TOR | Walker,R | Acquired via trade | DSP | | After |
| 7/3/2025 | TOR | Woodford | Traded away | DSP | | After |
| 7/3/2025 | TOR | Young,D | Traded away | DSP | | After |
| 7/4/2025 | TOR | Crow-Armstrong | Promoted to active roster | | | Before |
| 7/4/2025 | TOR | Keith | Demoted to reserve roster | | | Before |
| 7/7/2025 | NHP | Grisham | Demoted to reserve roster | | | Before |
| 7/7/2025 | NHP | Robles | Activated from Injured List | | | Before |
| 7/7/2025 | SPR | Candelario | Placed on Injured List | | 7/6/2025 | Before |
| 7/7/2025 | SPR | Flores | Promoted to active roster | | | Before |
| 7/7/2025 | WTB | Luzardo | Promoted to active roster | | | Before |
| 7/7/2025 | WTB | Williams,D | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Baker,L | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Carpenter,K | Promoted to active roster | | | Before |
| 7/10/2025 | CED | Corbin | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Fitts | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Freeland | Activated from Injured List | | | Before |
| 7/10/2025 | CED | Halvorsen | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Hays | Promoted to active roster | | | Before |
| 7/10/2025 | CED | Joe | Demoted to reserve roster | | | Before |
| 7/10/2025 | CED | Lynch | Activated from Injured List | | | Before |
| 7/13/2025 | NHP | Hamilton,I | Demoted to reserve roster | | | Before |
| 7/13/2025 | NHP | Hodge | Promoted to active roster | | | Before |
| 7/13/2025 | NHP | Nardi | Demoted to reserve roster | | | Before |
| 7/13/2025 | NHP | Nunez,D | Promoted to active roster | | | Before |
| 7/15/2025 | NDF | Matz | Traded away | DUR | | After |
| 7/15/2025 | NDF | Sanchez,G | Acquired via trade | DUR | | After |
| 7/16/2025 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 7/16/2025 | DSP | Knack | Promoted to active roster | | | Before |
| 7/16/2025 | DSP | Yamamoto | Promoted to active roster | | | Before |
| 7/16/2025 | DSP | Young,D | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Brown,B | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Butto | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Chargois | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Chargois | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Chargois | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Contreras,WE | Placed on Injured List | | 7/13/2025 | Before |
| 7/16/2025 | NDF | Crouse | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Foley | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Lopez,Jaco | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Malloy | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Millas | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Pereda | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Pereda | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Phillips,E | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Stallings | Placed on Injured List | | 7/7/2025 | Before |
| 7/16/2025 | NDF | Thompson,K | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Wagner | Demoted to reserve roster | | | Before |
| 7/16/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 7/16/2025 | NDF | Williams,T | Demoted to reserve roster | | | Before |
| 7/18/2025 | NDF | Foley | Traded away | HOL | | After |
| 7/18/2025 | NDF | Pauley | Traded away | HOL | | After |
| 7/18/2025 | NDF | Schneemann | Acquired via trade | HOL | | After |
| 7/18/2025 | NDF | Smith,J | Acquired via trade | HOL | | After |
| 7/18/2025 | NHP | Moncada | Traded away | HOL | | After |
| 7/18/2025 | NHP | Suzuki | Acquired via trade | HOL | | After |
| 7/19/2025 | CED | Minter | Demoted to reserve roster | | | Before |
| 7/19/2025 | CED | Treinen | Promoted to active roster | | | Before |
| 7/19/2025 | NDF | Arcia | Demoted to reserve roster | | | Before |
| 7/19/2025 | NDF | Brown,B | Demoted to reserve roster | | | Before |
| 7/19/2025 | NDF | Brown,B | Promoted to active roster | | | Before |
| 7/19/2025 | NDF | Butto | Promoted to active roster | | | Before |
| 7/19/2025 | NDF | Lopez,Jaco | Demoted to reserve roster | | | Before |
| 7/19/2025 | NDF | Schneemann | Promoted to active roster | | | Before |
| 7/19/2025 | NHP | Heyward | Demoted to reserve roster | | | Before |
| 7/19/2025 | SPR | Candelario | Activated from Injured List | | | Before |
| 7/19/2025 | SPR | Deluca | Promoted to active roster | | | Before |
| 7/19/2025 | SPR | Flores | Demoted to reserve roster | | | Before |
| 7/19/2025 | SPR | Meadows | Placed on Injured List | | 7/19/2025 | Before |
| 7/19/2025 | SPR | Shuster | Demoted to reserve roster | | | Before |
| 7/19/2025 | SPR | Thornton | Promoted to active roster | | | Before |
| 7/22/2025 | DSP | Baty | Promoted to active roster | | | Before |
| 7/22/2025 | DSP | McCutchen | Placed on Injured List | | 7/18/2025 | Before |
| 7/22/2025 | SPR | Benson | Promoted to active roster | | | Before |
| 7/22/2025 | SPR | Harris II | Placed on Injured List | | 7/21/2025 | Before |
| 7/28/2025 | CHI | Bido | Demoted to reserve roster | | | Before |
| 7/28/2025 | CHI | Kershaw | Promoted to active roster | | | Before |
| 7/28/2025 | CHI | Leahy | Promoted to active roster | | | Before |
| 7/28/2025 | CHI | Turnbull | Demoted to reserve roster | | | Before |
| 7/28/2025 | NHP | Coulombe | Demoted to reserve roster | | | Before |
| 7/28/2025 | NHP | Hamilton,I | Promoted to active roster | | | Before |
| 7/28/2025 | NHP | Nardi | Promoted to active roster | | | Before |
| 7/28/2025 | NHP | Scherzer | Promoted to active roster | | | Before |
| 7/28/2025 | NHP | Tinoco | Demoted to reserve roster | | | Before |
| 7/28/2025 | NHP | Waldron | Placed on Injured List | | 7/26/2025 | Before |
| 7/31/2025 | DSP | McCutchen | Activated from Injured List | | | Before |
| 7/31/2025 | DSP | Soriano,J | Demoted to reserve roster | | | Before |
| 8/3/2025 | NDF | Stallings | Activated from Injured List | | | Before |
| 8/3/2025 | NDF | Tatis | Placed on Injured List | | 7/29/2025 | Before |
| 8/3/2025 | SPR | Benson | Demoted to reserve roster | | | Before |
| 8/3/2025 | SPR | Meadows | Activated from Injured List | | | Before |
| 8/6/2025 | NDF | Brown,B | Promoted to active roster | | | Before |
| 8/6/2025 | NDF | Francis | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Herz | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Millas | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Musgrove | Promoted to active roster | | | Before |
| 8/6/2025 | NDF | Schneemann | Demoted to reserve roster | | | Before |
| 8/6/2025 | NDF | Thompson,K | Promoted to active roster | | | Before |
| 8/6/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 8/12/2025 | SPR | Deluca | Demoted to reserve roster | | | Before |
| 8/12/2025 | SPR | Harris II | Activated from Injured List | | | Before |
| 8/15/2025 | NDF | Brown,B | Demoted to reserve roster | | | Before |
| 8/15/2025 | NDF | Cousins | Demoted to reserve roster | | | Before |
| 8/15/2025 | NDF | Francis | Promoted to active roster | | | Before |
| 8/15/2025 | NDF | Lopez,Jaco | Promoted to active roster | | | Before |
| 8/15/2025 | NHP | Fitzgerald | Demoted to reserve roster | | | Before |
| 8/15/2025 | NHP | Grisham | Promoted to active roster | | | Before |
| 8/15/2025 | NHP | Madrigal | Promoted to active roster | | | Before |
| 8/15/2025 | NHP | Robles | Demoted to reserve roster | | | Before |
| 8/15/2025 | NHP | Scherzer | Demoted to reserve roster | | | Before |
| 8/15/2025 | NHP | Waldron | Activated from Injured List | | | Before |
| 8/18/2025 | NHP | deGrom | Promoted to active roster | | | Before |
| 8/18/2025 | NHP | Lopez,R | Placed on Injured List | | 8/16/2025 | Before |
| 8/21/2025 | CED | Halvorsen | Promoted to active roster | | | Before |
| 8/21/2025 | CED | Hernandez,D | Demoted to reserve roster | | | Before |
| 8/21/2025 | DSP | Darvish | Promoted to active roster | | | Before |
| 8/21/2025 | DSP | McCutchen | Placed on Injured List | | 8/21/2025 | Before |
| 8/21/2025 | DSP | Morgan | Placed on Injured List | | 8/20/2025 | Before |
| 8/21/2025 | DSP | Soriano,J | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Aldegheri | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Bellinger | Placed on Injured List | | 8/20/2025 | Before |
| 8/21/2025 | NDF | Contreras,WE | Activated from Injured List | | | Before |
| 8/21/2025 | NDF | Loperfido | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Lopez,Jaco | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | McDonald | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Millas | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Millas | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Sanchez,G | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Schneemann | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Schneemann | Promoted to active roster | | | Before |
| 8/21/2025 | NDF | Thompson,K | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Wagner | Demoted to reserve roster | | | Before |
| 8/21/2025 | NDF | Wagner | Promoted to active roster | | | Before |
| 8/21/2025 | TOR | Suter | Demoted to reserve roster | | | Before |
| 8/21/2025 | TOR | Uceta | Promoted to active roster | | | Before |
| 8/24/2025 | CED | Birdsong | Promoted to active roster | | | Before |
| 8/24/2025 | CED | Lynch | Demoted to reserve roster | | | Before |
| 8/24/2025 | NDF | Contreras,WE | Placed on Injured List | | 8/23/2025 | Before |
| 8/24/2025 | NDF | Millas | Promoted to active roster | | | Before |
| 8/24/2025 | TOR | Alvarez,Y | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Betts | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Goodman | Promoted to active roster | | | Before |
| 8/24/2025 | TOR | Greene,H | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Keith | Promoted to active roster | | | Before |
| 8/24/2025 | TOR | Manoah | Promoted to active roster | | | Before |
| 8/24/2025 | TOR | Pepiot | Demoted to reserve roster | | | Before |
| 8/24/2025 | TOR | Rodriguez,E | Promoted to active roster | | | Before |
| 8/27/2025 | CED | Fitts | Promoted to active roster | | | Before |
| 8/27/2025 | CED | Hampson | Demoted to reserve roster | | | Before |
| 8/27/2025 | CED | Mlodzinski | Promoted to active roster | | | Before |
| 8/27/2025 | CED | Nunez,N | Promoted to active roster | | | Before |
| 8/27/2025 | CED | Quantrill | Demoted to reserve roster | | | Before |
| 8/27/2025 | CED | Voth | Demoted to reserve roster | | | Before |
| 8/27/2025 | NHP | deGrom | Demoted to reserve roster | | | Before |
| 8/27/2025 | NHP | Scherzer | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Boyle | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Brieske | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Darvish | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | German | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Gil | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Knack | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | McCann,K | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Raleigh | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Rea | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Soler | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Soriano,J | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Stanek | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Suwinski | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Woodford | Promoted to active roster | | | Before |
| 9/5/2025 | DSP | Yamamoto | Demoted to reserve roster | | | Before |
| 9/5/2025 | DSP | Young,D | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Carlson | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Cecconi | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Dezenzo | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Hamilton,I | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | Kwan | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | McDermott | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Nardi | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | Nelson,R | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | Nunez,D | Demoted to reserve roster | | | Before |
| 9/5/2025 | NHP | Rizzo | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Strider | Promoted to active roster | | | Before |
| 9/5/2025 | NHP | Suzuki | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Carpenter,K | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Fitts | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Halvorsen | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Hampson | Promoted to active roster | | | Before |
| 9/8/2025 | CED | Hernandez,C | Promoted to active roster | | | Before |
| 9/8/2025 | CED | Madden | Promoted to active roster | | | Before |
| 9/8/2025 | CED | Treinen | Demoted to reserve roster | | | Before |
| 9/8/2025 | CED | Voth | Promoted to active roster | | | Before |